SYRE vs DAR

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Darling Ingredients Inc (DAR, Company).

SYRE is from the Healthcare sector, while DAR is from the Consumer Defensive sector.

5-Year PerformanceDAR has outperformed SYRE, delivering a return of -3.4% compared to -8.5%

SYRE vs DAR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	DAR(COMPANY)
Market Cap	$9.19B	$9.18B
Max Drawdown	99.11%	91.67%
Sharpe Ratio	2.99	1.97
5Y Beta	1.79	0.75
Industry	Biotechnology	Packaged Foods
P/E Ratio	-45.95	65.42
Forward P/E	N/A	14.08
PEG Ratio	N/A	4.31
5Y EPS CAGR	-2.73%	79.78%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.27%	6.36%
P/S Ratio	650.22	1.48
P/B Ratio	16.58	1.91

Market Cap

Winner

SYRE

$9.19B

DAR

$9.18B

Max Drawdown

SYRE

99.11%

Winner

DAR

91.67%

Sharpe Ratio

Winner

SYRE

2.99

DAR

1.97

5Y Beta

SYRE

1.79

Winner

DAR

0.75

Industry

SYRE

Biotechnology

DAR

Packaged Foods

P/E Ratio

Winner

SYRE

-45.95

DAR

65.42

Forward P/E

SYRE

N/A

DAR

14.08

PEG Ratio

SYRE

N/A

DAR

4.31

5Y EPS CAGR

SYRE

-2.73%

Winner

DAR

79.78%

Debt to Equity

SYRE

0.00%

DAR

0.00%

Free Cash Flow Yield

SYRE

-2.27%

Winner

DAR

6.36%

P/S Ratio

SYRE

650.22

Winner

DAR

1.48

P/B Ratio

SYRE

16.58

Winner

DAR

1.91

SYRE vs DAR - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	DAR
1 month	+11.33%	+2.03%
3 months	+43.52%	-4.59%
6 months	+198.72%	+23.26%
1 year	+588.39%	+93.58%
5 years(CAGR)	-8.54%	-3.45%
10 years(CAGR)	-0.91%	+14.79%
Max(CAGR)	-7.85%	+15.97%

Winner

SYRE

+11.33%

DAR

+2.03%

Winner

SYRE

+43.52%

DAR

-4.59%

Winner

SYRE

+198.72%

DAR

+23.26%

Winner

SYRE

+588.39%

DAR

+93.58%

5Y(CAGR)

SYRE

-8.54%

Winner

DAR

-3.45%

10Y(CAGR)

SYRE

-0.91%

Winner

DAR

+14.79%

Max(CAGR)

SYRE

-7.85%

Winner

DAR

+15.97%

SYRE vs DAR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	DAR
2026	+243.07%	+57.84%
2025	+37.36%	+4.93%
2024	+8.79%	-33.26%
2023	+104.27%	-18.31%
2022	-90.57%	-10.38%
2021	-44.51%	+21.71%
2020	+1.55%	+104.03%
2019	-4.98%	+46.17%
2018	+39.22%	+5.08%
2017	+18.38%	+35.30%
2016	-55.48%	+19.10%
2015	N/A	-42.07%
2014	N/A	-14.06%
2013	N/A	+26.16%
2012	N/A	+19.43%
2011	N/A	-0.08%
2010	N/A	+51.60%
2009	N/A	+41.32%
2008	N/A	-52.43%
2007	N/A	+109.42%
2006	N/A	+40.20%
2005	N/A	-11.38%
2004	N/A	+54.61%
2003	N/A	+50.82%
2002	N/A	+155.71%
2001	N/A	+60.00%
2000	N/A	-81.25%
1999	N/A	+88.89%

SYRE vs DAR Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for DAR was -91.67%, occurring on Sep 20, 2000. Recovery took 1027 trading sessions.

The current SYRE drawdown is -65.00%. The current DAR drawdown is -31.85%.

Rank	SYRE	DAR
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-91.67% Nov 9, 1999 - Dec 11, 2003
#2	N/A	-83.00% Jun 19, 2008 - May 16, 2011
#3	N/A	-68.31% Jun 7, 2022 - Apr 8, 2025
#4	N/A	-66.78% Oct 24, 2013 - Dec 6, 2019
#5	N/A	-52.38% Jan 29, 2020 - Aug 7, 2020
#6	N/A	-38.96% May 31, 2011 - May 10, 2013
#7	N/A	-31.37% Jul 30, 2004 - Mar 15, 2006
#8	N/A	-29.24% Jul 9, 2007 - Oct 17, 2007
#9	N/A	-29.00% Nov 1, 2021 - Apr 20, 2022
#10	N/A	-22.75% Apr 26, 2004 - Jun 24, 2004
#11	N/A	-21.36% Mar 15, 2021 - Oct 25, 2021
#12	N/A	-20.49% Apr 18, 2006 - Dec 6, 2006
#13	N/A	-16.51% Apr 20, 2022 - Jun 7, 2022
#14	N/A	-16.24% Feb 28, 2008 - Apr 17, 2008
#15	N/A	-16.07% Dec 12, 2003 - Mar 29, 2004

Correlation

Correlation between SYRE and DAR is -0.42 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.42

-101