SYK vs VRTX

Comparison between Stryker Corp (SYK, Company) and Vertex Pharmaceuticals Inc (VRTX, Company).

Both SYK and VRTX are from the Healthcare sector.

5-Year PerformanceVRTX has outperformed SYK, delivering a return of +22.1% compared to +5.8%

SYK vs VRTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYK(COMPANY)	VRTX(COMPANY)
Market Cap	$133B	$133B
Max Drawdown	59.22%	91.77%
Sharpe Ratio	-0.48	1.06
5Y Beta	0.54	0.49
Industry	Medical Devices	Biotechnology
P/E Ratio	35.31	30.30
Forward P/E	22.03	27.03
PEG Ratio	1.70	1.34
Dividend Yield	1.05%	N/A
5Y Dividends CAGR	11.88%	N/A
5Y EPS CAGR	13.54%	17.73%
Debt to Equity	62.29%	0.00%
Free Cash Flow Yield	3.53%	2.85%
P/S Ratio	5.04	10.18
P/B Ratio	5.53	6.56

Market Cap

SYK

$133B

Winner

VRTX

$133B

Max Drawdown

Winner

SYK

59.22%

VRTX

91.77%

Sharpe Ratio

SYK

-0.48

Winner

VRTX

1.06

5Y Beta

SYK

0.54

Winner

VRTX

0.49

Industry

SYK

Medical Devices

VRTX

Biotechnology

P/E Ratio

SYK

35.31

Winner

VRTX

30.30

Forward P/E

Winner

SYK

22.03

VRTX

27.03

PEG Ratio

SYK

1.70

Winner

VRTX

1.34

Dividend Yield

SYK

1.05%

VRTX

N/A

5Y Dividends CAGR

SYK

11.88%

VRTX

N/A

5Y EPS CAGR

SYK

13.54%

Winner

VRTX

17.73%

Debt to Equity

SYK

62.29%

Winner

VRTX

0.00%

Free Cash Flow Yield

Winner

SYK

3.53%

VRTX

2.85%

P/S Ratio

Winner

SYK

5.04

VRTX

10.18

P/B Ratio

Winner

SYK

5.53

VRTX

6.56

SYK vs VRTX - Historical Returns

Returns include dividend reinvestment.

Period	SYK	VRTX
1 month	+3.60%	+8.76%
3 months	+6.09%	+20.98%
6 months	-11.70%	+12.31%
1 year	-12.27%	+35.48%
5 years(CAGR)	+5.77%	+22.09%
10 years(CAGR)	+12.52%	+18.22%
Max(CAGR)	+13.09%	+14.75%

SYK

+3.60%

Winner

VRTX

+8.76%

SYK

+6.09%

Winner

VRTX

+20.98%

SYK

-11.70%

Winner

VRTX

+12.31%

SYK

-12.27%

Winner

VRTX

+35.48%

5Y(CAGR)

SYK

+5.77%

Winner

VRTX

+22.09%

10Y(CAGR)

SYK

+12.52%

Winner

VRTX

+18.22%

Max(CAGR)

SYK

+13.09%

Winner

VRTX

+14.75%

SYK vs VRTX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYK	VRTX
2026	-4.31%	+16.82%
2025	-1.12%	+11.73%
2024	+22.66%	-2.00%
2023	+23.01%	+42.26%
2022	-7.77%	+29.77%
2021	+13.00%	-4.28%
2020	+17.86%	+7.70%
2019	+37.30%	+33.44%
2018	+0.45%	+8.37%
2017	+31.25%	+100.11%
2016	+34.91%	-40.05%
2015	+0.38%	+2.24%
2014	+28.28%	+60.91%
2013	+36.65%	+70.22%
2012	+9.11%	+30.00%
2011	-7.64%	-7.72%
2010	+4.18%	-20.82%
2009	+22.54%	+39.62%
2008	-45.17%	+31.23%
2007	+36.15%	-37.05%
2006	+24.06%	+34.12%
2005	-7.69%	+170.21%
2004	+15.43%	+0.67%
2003	+25.19%	-36.74%
2002	+17.50%	-35.41%
2001	+20.31%	-61.05%
2000	+48.20%	+281.33%
1999	+11.72%	+32.38%

SYK vs VRTX Drawdown Comparison

The maximum drawdown for SYK was -58.62%, occurring on Mar 9, 2009. Recovery took 1441 trading sessions.

The maximum drawdown for VRTX was -91.77%, occurring on Nov 11, 2003. Recovery took 3434 trading sessions.

The current SYK drawdown is -17.04%. The current VRTX drawdown is -0.28%.

Rank	SYK	VRTX
#1	-58.62% Dec 26, 2007 - Sep 17, 2013	-91.77% Nov 2, 2000 - Jul 2, 2014
#2	-43.80% Feb 19, 2020 - Oct 12, 2020	-55.25% Mar 6, 2000 - Jun 16, 2000
#3	-35.95% Jan 19, 2000 - Jun 14, 2000	-49.10% Aug 19, 2015 - Jul 19, 2017
#4	-31.68% Sep 8, 2021 - Feb 1, 2023	-41.60% Jul 20, 2020 - Aug 15, 2022
#5	-30.45% Jul 7, 2004 - Jan 9, 2007	-29.08% Sep 28, 2000 - Oct 25, 2000
#6	-29.45% Jul 25, 2025 - May 11, 2026	-29.07% Nov 8, 2024 - Jul 2, 2026
#7	-26.85% Feb 27, 2002 - Oct 10, 2002	-22.82% Jul 12, 2000 - Aug 16, 2000
#8	-24.26% Jul 27, 2001 - Feb 27, 2002	-21.18% Sep 28, 2018 - Jan 18, 2019
#9	-19.74% Jul 26, 2000 - Nov 2, 2000	-19.52% Jan 21, 2000 - Feb 7, 2000
#10	-18.90% Jun 6, 2018 - Jan 30, 2019	-19.39% Feb 11, 2020 - Apr 6, 2020
#11	-18.18% Dec 6, 2000 - Feb 23, 2001	-17.73% Mar 12, 2018 - Jul 12, 2018
#12	-16.57% Jun 30, 2023 - Jan 10, 2024	-17.36% Jul 24, 2017 - Jan 23, 2018
#13	-15.79% Mar 1, 2001 - Apr 25, 2001	-15.45% Jan 18, 2019 - Oct 29, 2019
#14	-15.61% Aug 19, 2015 - Mar 10, 2016	-15.26% Jan 22, 2015 - Mar 16, 2015
#15	-15.45% Jan 27, 2025 - Jul 23, 2025	-14.46% Jul 11, 2014 - Sep 19, 2014