SLNO vs WERN

Comparison between Soleno Therapeutics Inc (SLNO, Company) and Werner Enterprises Inc (WERN, Company).

SLNO is from the Healthcare sector, while WERN is from the Industrials sector.

5-Year PerformanceSLNO has outperformed WERN, delivering a return of +28.5% compared to +1.1%

SLNO vs WERN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SLNO(COMPANY)	WERN(COMPANY)
Market Cap	$2.74B	$2.75B
Max Drawdown	99.86%	53.19%
Sharpe Ratio	-0.21	1.39
5Y Beta	N/A	0.80
Industry	Biotechnology	Trucking
P/E Ratio	29.02	-321.15
Forward P/E	13.12	42.92
Dividend Yield	N/A	1.22%
5Y Dividends CAGR	N/A	11.84%
Debt to Equity	10.06%	64.92%
Free Cash Flow Yield	3.85%	-1.59%

Market Cap

SLNO

$2.74B

Winner

WERN

$2.75B

Max Drawdown

SLNO

99.86%

Winner

WERN

53.19%

Sharpe Ratio

SLNO

-0.21

Winner

WERN

1.39

5Y Beta

SLNO

N/A

WERN

0.80

Industry

SLNO

Biotechnology

WERN

Trucking

P/E Ratio

SLNO

29.02

Winner

WERN

-321.15

Forward P/E

Winner

SLNO

13.12

WERN

42.92

Dividend Yield

SLNO

N/A

WERN

1.22%

5Y Dividends CAGR

SLNO

N/A

WERN

11.84%

Debt to Equity

Winner

SLNO

10.06%

WERN

64.92%

Free Cash Flow Yield

Winner

SLNO

3.85%

WERN

-1.59%

SLNO vs WERN - Historical Returns

Returns include dividend reinvestment.

Period	SLNO	WERN
1 month	+0.65%	+7.37%
3 months	+34.51%	+29.91%
6 months	+12.79%	+30.75%
1 year	-29.86%	+55.98%
5 years(CAGR)	+28.47%	+1.11%
10 years(CAGR)	-5.91%	+8.25%
Max(CAGR)	-13.75%	+8.73%

SLNO

+0.65%

Winner

WERN

+7.37%

Winner

SLNO

+34.51%

WERN

+29.91%

SLNO

+12.79%

Winner

WERN

+30.75%

SLNO

-29.86%

Winner

WERN

+55.98%

5Y(CAGR)

Winner

SLNO

+28.47%

WERN

+1.11%

10Y(CAGR)

SLNO

-5.91%

Winner

WERN

+8.25%

Max(CAGR)

SLNO

-13.75%

Winner

WERN

+8.73%

SLNO vs WERN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SLNO	WERN
2026	+12.38%	+45.18%
2025	+1.29%	-14.28%
2024	+18.45%	-13.23%
2023	+1737.90%	+5.47%
2022	-70.09%	-13.62%
2021	-79.60%	+24.07%
2020	-31.07%	+9.18%
2019	+53.93%	+37.02%
2018	-6.56%	-23.31%
2017	-55.56%	+40.72%
2016	-56.22%	+16.72%
2015	+23.33%	-24.23%
2014	-61.56%	+28.10%
2013	N/A	+10.76%
2012	N/A	-4.53%
2011	N/A	+7.80%
2010	N/A	+22.56%
2009	N/A	+21.36%
2008	N/A	+16.82%
2007	N/A	-5.43%
2006	N/A	-11.48%
2005	N/A	-11.63%
2004	N/A	+14.00%
2003	N/A	+12.63%
2002	N/A	+18.48%
2001	N/A	+58.28%
2000	N/A	+25.68%
1999	N/A	-13.16%

SLNO vs WERN Drawdown Comparison

The maximum drawdown for SLNO was -99.86%, occurring on Dec 15, 2022. This drawdown has not yet recovered.

The maximum drawdown for WERN was -51.13%, occurring on Nov 20, 2025. Recovery took 867 trading sessions.

The current SLNO drawdown is -91.92%. The current WERN drawdown is -7.15%.

Rank	SLNO	WERN
#1	-99.86% Mar 4, 2015 - Dec 15, 2022	-51.13% Feb 2, 2023 - Jul 21, 2026
#2	-70.79% Nov 17, 2014 - Feb 19, 2015	-45.62% Sep 19, 2008 - Jan 13, 2010
#3	-9.74% Feb 26, 2015 - Mar 3, 2015	-45.09% Apr 28, 2000 - Jan 25, 2001
#4	-8.35% Feb 24, 2015 - Feb 26, 2015	-34.83% Mar 19, 2015 - Aug 28, 2017
#5	-7.31% Feb 19, 2015 - Feb 23, 2015	-32.72% Jun 29, 2001 - Dec 4, 2001
#6	N/A	-31.68% Jan 29, 2018 - Oct 22, 2019
#7	N/A	-30.45% Dec 28, 2004 - Jul 18, 2008
#8	N/A	-29.76% Nov 3, 1999 - Apr 12, 2000
#9	N/A	-25.71% Feb 6, 2020 - Apr 17, 2020
#10	N/A	-23.90% Apr 4, 2011 - Jan 31, 2012
#11	N/A	-23.79% May 10, 2021 - Feb 1, 2023
#12	N/A	-22.46% Jan 30, 2002 - Oct 21, 2002
#13	N/A	-21.82% Feb 13, 2001 - Apr 26, 2001
#14	N/A	-21.02% Nov 27, 2002 - Apr 28, 2003
#15	N/A	-19.04% Aug 26, 2020 - Mar 11, 2021

Correlation

Correlation between SLNO and WERN is -0.50 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.50

-101