SLNO vs UPST

Comparison between Soleno Therapeutics Inc (SLNO, Company) and Upstart Holdings Inc (UPST, Company).

SLNO is from the Healthcare sector, while UPST is from the Financial Services sector.

5-Year PerformanceSLNO has outperformed UPST, delivering a return of +28.5% compared to -25.0%

SLNO vs UPST - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SLNO(COMPANY)	UPST(COMPANY)
Market Cap	$2.74B	$2.74B
Max Drawdown	99.86%	96.90%
Sharpe Ratio	-0.21	-1.12
5Y Beta	N/A	2.59
Industry	Biotechnology	Credit Services
P/E Ratio	29.02	98.71
Forward P/E	13.12	36.50
Debt to Equity	10.06%	0.00%
Free Cash Flow Yield	3.85%	-14.32%

Market Cap

Winner

SLNO

$2.74B

UPST

$2.74B

Max Drawdown

SLNO

99.86%

Winner

UPST

96.90%

Sharpe Ratio

Winner

SLNO

-0.21

UPST

-1.12

5Y Beta

SLNO

N/A

UPST

2.59

Industry

SLNO

Biotechnology

UPST

Credit Services

P/E Ratio

Winner

SLNO

29.02

UPST

98.71

Forward P/E

Winner

SLNO

13.12

UPST

36.50

Debt to Equity

SLNO

10.06%

Winner

UPST

0.00%

Free Cash Flow Yield

Winner

SLNO

3.85%

UPST

-14.32%

SLNO vs UPST - Historical Returns

Returns include dividend reinvestment.

Period	SLNO	UPST
1 month	+0.65%	-12.30%
3 months	+34.51%	-15.94%
6 months	+12.79%	-39.08%
1 year	-29.86%	-67.21%
5 years(CAGR)	+28.47%	-25.04%
10 years(CAGR)	-5.91%	N/A
Max(CAGR)	-13.75%	-1.17%

Winner

SLNO

+0.65%

UPST

-12.30%

Winner

SLNO

+34.51%

UPST

-15.94%

Winner

SLNO

+12.79%

UPST

-39.08%

Winner

SLNO

-29.86%

UPST

-67.21%

5Y(CAGR)

Winner

SLNO

+28.47%

UPST

-25.04%

10Y(CAGR)

SLNO

-5.91%

UPST

N/A

Max(CAGR)

SLNO

-13.75%

Winner

UPST

-1.17%

SLNO vs UPST - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SLNO	UPST
2026	+12.38%	-39.81%
2025	+1.29%	-28.08%
2024	+18.45%	+58.69%
2023	+1737.90%	+216.99%
2022	-70.09%	-90.86%
2021	-79.60%	+243.94%
2020	-31.07%	+38.28%
2019	+53.93%	N/A
2018	-6.56%	N/A
2017	-55.56%	N/A
2016	-56.22%	N/A
2015	+23.33%	N/A
2014	-61.56%	N/A

SLNO vs UPST Drawdown Comparison

The maximum drawdown for SLNO was -99.86%, occurring on Dec 15, 2022. This drawdown has not yet recovered.

The maximum drawdown for UPST was -96.90%, occurring on May 2, 2023. This drawdown has not yet recovered.

The current SLNO drawdown is -91.92%. The current UPST drawdown is -92.93%.

Rank	SLNO	UPST
#1	-99.86% Mar 4, 2015 - Dec 15, 2022	-96.90% Oct 15, 2021 - May 2, 2023
#2	-70.79% Nov 17, 2014 - Feb 19, 2015	-54.13% Feb 12, 2021 - Mar 18, 2021
#3	-9.74% Feb 26, 2015 - Mar 3, 2015	-49.02% Mar 22, 2021 - May 27, 2021
#4	-8.35% Feb 24, 2015 - Feb 26, 2015	-33.48% Jun 7, 2021 - Aug 11, 2021
#5	-7.31% Feb 19, 2015 - Feb 23, 2015	-18.75% Dec 22, 2020 - Jan 5, 2021
#6	N/A	-13.85% Sep 23, 2021 - Oct 13, 2021
#7	N/A	-13.39% May 27, 2021 - Jun 7, 2021
#8	N/A	-13.12% Jan 12, 2021 - Jan 21, 2021
#9	N/A	-8.67% Aug 18, 2021 - Aug 24, 2021
#10	N/A	-7.68% Jan 25, 2021 - Feb 1, 2021
#11	N/A	-7.10% Sep 9, 2021 - Sep 16, 2021
#12	N/A	-6.78% Dec 18, 2020 - Dec 22, 2020
#13	N/A	-5.66% Feb 3, 2021 - Feb 9, 2021
#14	N/A	-4.80% Jan 7, 2021 - Jan 12, 2021
#15	N/A	-3.38% Aug 27, 2021 - Aug 31, 2021