SION vs ZYME
Comparison between Sionna Therapeutics Inc (SION, Company) and Zymeworks BC Inc (ZYME, Company).
Both SION and ZYME are from the Healthcare sector.
SION vs ZYME - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
SION
$1.88B
Winner
ZYME
$1.88B
Max Drawdown
Winner
SION
69.36%
ZYME
91.81%
Sharpe Ratio
SION
1.46
Winner
ZYME
1.59
5Y Beta
SION
0.92
Winner
ZYME
0.84
Industry
SION
Biotechnology
ZYME
Biotechnology
P/E Ratio
Winner
SION
-21.73
ZYME
-18.56
Forward P/E
SION
N/A
ZYME
25.71
PEG Ratio
SION
N/A
ZYME
0.00
Debt to Equity
SION
0.00%
ZYME
0.00%
Free Cash Flow Yield
Winner
SION
-3.84%
ZYME
-4.10%
P/S Ratio
SION
N/A
ZYME
23.29
P/B Ratio
Winner
SION
6.52
ZYME
11.55
SION vs ZYME - Historical Returns
Returns include dividend reinvestment.
1M
Winner
SION
+20.59%
ZYME
+9.12%
3M
Winner
SION
+8.64%
ZYME
+1.98%
6M
Winner
SION
+12.19%
ZYME
-1.16%
1Y
Winner
SION
+110.78%
ZYME
+104.11%
5Y(CAGR)
SION
N/A
ZYME
-6.33%
10Y(CAGR)
SION
N/A
ZYME
+7.98%
Max(CAGR)
Winner
SION
+49.89%
ZYME
+7.98%
SION vs ZYME - Annual Returns (2017 - 2026)
Returns include dividend reinvestment.
| Year | SION | ZYME |
|---|---|---|
| 2026 | +12.19% | -1.16% |
| 2025 | +64.56% | +78.15% |
| 2024 | N/A | +41.04% |
| 2023 | N/A | +37.80% |
| 2022 | N/A | -53.71% |
| 2021 | N/A | -66.53% |
| 2020 | N/A | -0.69% |
| 2019 | N/A | +209.46% |
| 2018 | N/A | +85.05% |
| 2017 | N/A | -41.59% |
SION vs ZYME Drawdown Comparison
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The maximum drawdown for ZYME was -91.81%, occurring on Sep 7, 2022. This drawdown has not yet recovered.
The current SION drawdown is -4.27%. The current ZYME drawdown is -53.69%.
| Rank | SION | ZYME |
|---|---|---|
| #1 | -69.36% Feb 7, 2025 - Aug 26, 2025 | -91.81% Jan 8, 2021 - Sep 7, 2022 |
| #2 | -27.07% May 11, 2026 - Jun 8, 2026 | -51.24% Jan 22, 2020 - Nov 27, 2020 |
| #3 | -23.74% Feb 3, 2026 - Apr 15, 2026 | -51.20% May 3, 2017 - Feb 1, 2018 |
| #4 | -19.06% Oct 21, 2025 - Nov 21, 2025 | -49.91% Jun 1, 2018 - Jun 24, 2019 |
| #5 | -18.12% Nov 24, 2025 - Feb 3, 2026 | -28.19% Feb 1, 2018 - Apr 26, 2018 |
| #6 | -17.26% Apr 16, 2026 - May 11, 2026 | -14.72% Sep 6, 2019 - Oct 17, 2019 |
| #7 | -15.94% Aug 28, 2025 - Sep 22, 2025 | -14.38% Dec 4, 2020 - Jan 8, 2021 |
| #8 | -5.53% Oct 3, 2025 - Oct 15, 2025 | -10.39% Apr 27, 2018 - May 15, 2018 |
| #9 | -3.56% Sep 29, 2025 - Oct 3, 2025 | -10.05% Dec 4, 2019 - Dec 18, 2019 |
| #10 | -2.41% Oct 16, 2025 - Oct 21, 2025 | -8.78% Jan 2, 2020 - Jan 17, 2020 |
| #11 | -0.36% Aug 26, 2025 - Aug 28, 2025 | -8.26% Nov 5, 2019 - Nov 18, 2019 |
| #12 | N/A | -7.96% Jul 9, 2019 - Aug 15, 2019 |
| #13 | N/A | -6.40% Aug 16, 2019 - Aug 28, 2019 |
| #14 | N/A | -4.63% May 30, 2018 - Jun 1, 2018 |
| #15 | N/A | -3.62% Nov 29, 2019 - Dec 4, 2019 |
Correlation
Correlation between SION and ZYME is 0.95 which considered as a very strong positive correlation - the stocks move almost identically together.
0.95
-101
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