SION vs NUVB
Comparison between Sionna Therapeutics Inc (SION, Company) and Nuvation Bio Inc - Class A (NUVB, Company).
Both SION and NUVB are from the Healthcare sector.
SION vs NUVB - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
SION
$1.88B
Winner
NUVB
$1.88B
Max Drawdown
Winner
SION
69.36%
NUVB
93.39%
Sharpe Ratio
SION
1.46
Winner
NUVB
1.59
5Y Beta
Winner
SION
0.92
NUVB
1.49
Industry
SION
Biotechnology
NUVB
Biotechnology
P/E Ratio
Winner
SION
-21.73
NUVB
-12.61
Debt to Equity
Winner
SION
0.00%
NUVB
16.62%
Free Cash Flow Yield
Winner
SION
-3.84%
NUVB
-6.69%
P/S Ratio
SION
N/A
NUVB
13.19
P/B Ratio
SION
6.52
Winner
NUVB
5.91
SION vs NUVB - Historical Returns
Returns include dividend reinvestment.
1M
Winner
SION
+20.59%
NUVB
+16.33%
3M
SION
+8.64%
Winner
NUVB
+29.25%
6M
Winner
SION
+12.19%
NUVB
-33.57%
1Y
SION
+110.78%
Winner
NUVB
+178.05%
5Y(CAGR)
SION
N/A
NUVB
-9.52%
Max(CAGR)
Winner
SION
+49.89%
NUVB
-9.16%
SION vs NUVB - Annual Returns (2020 - 2026)
Returns include dividend reinvestment.
| Year | SION | NUVB |
|---|---|---|
| 2026 | +12.19% | -33.57% |
| 2025 | +64.56% | +245.95% |
| 2024 | N/A | +69.43% |
| 2023 | N/A | -25.25% |
| 2022 | N/A | -78.26% |
| 2021 | N/A | -24.11% |
| 2020 | N/A | +17.00% |
SION vs NUVB Drawdown Comparison
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The maximum drawdown for NUVB was -93.39%, occurring on Oct 31, 2023. This drawdown has not yet recovered.
The current SION drawdown is -4.27%. The current NUVB drawdown is -60.88%.
| Rank | SION | NUVB |
|---|---|---|
| #1 | -69.36% Feb 7, 2025 - Aug 26, 2025 | -93.39% Mar 19, 2021 - Oct 31, 2023 |
| #2 | -27.07% May 11, 2026 - Jun 8, 2026 | -23.73% Jan 5, 2021 - Mar 9, 2021 |
| #3 | -23.74% Feb 3, 2026 - Apr 15, 2026 | -13.87% Sep 15, 2020 - Dec 31, 2020 |
| #4 | -19.06% Oct 21, 2025 - Nov 21, 2025 | -5.16% Sep 1, 2020 - Sep 10, 2020 |
| #5 | -18.12% Nov 24, 2025 - Feb 3, 2026 | -4.27% Dec 31, 2020 - Jan 5, 2021 |
| #6 | -17.26% Apr 16, 2026 - May 11, 2026 | -3.00% Aug 24, 2020 - Sep 1, 2020 |
| #7 | -15.94% Aug 28, 2025 - Sep 22, 2025 | -2.09% Sep 10, 2020 - Sep 15, 2020 |
| #8 | -5.53% Oct 3, 2025 - Oct 15, 2025 | -2.06% Mar 16, 2021 - Mar 19, 2021 |
| #9 | -3.56% Sep 29, 2025 - Oct 3, 2025 | -0.58% Mar 11, 2021 - Mar 15, 2021 |
| #10 | -2.41% Oct 16, 2025 - Oct 21, 2025 | N/A |
| #11 | -0.36% Aug 26, 2025 - Aug 28, 2025 | N/A |
Correlation
Correlation between SION and NUVB is 0.85 which considered as a strong positive correlation - the stocks tend to move together.
0.85
-101
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