SION vs PRLB
Comparison between Sionna Therapeutics Inc (SION, Company) and Proto Labs Inc (PRLB, Company).
SION is from the Healthcare sector, while PRLB is from the Industrials sector.
SION vs PRLB - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
SION
$1.88B
PRLB
$1.87B
Max Drawdown
Winner
SION
69.36%
PRLB
91.22%
Sharpe Ratio
SION
1.46
Winner
PRLB
1.55
5Y Beta
Winner
SION
0.92
PRLB
1.52
Industry
SION
Biotechnology
PRLB
Metal Fabrication
P/E Ratio
Winner
SION
-21.73
PRLB
72.57
Forward P/E
SION
N/A
PRLB
32.26
PEG Ratio
SION
N/A
PRLB
0.93
5Y EPS CAGR
SION
N/A
PRLB
-6.44%
Debt to Equity
SION
0.00%
PRLB
0.00%
Free Cash Flow Yield
SION
-3.84%
Winner
PRLB
3.02%
P/S Ratio
SION
N/A
PRLB
3.43
P/B Ratio
SION
6.52
Winner
PRLB
2.74
SION vs PRLB - Historical Returns
Returns include dividend reinvestment.
1M
Winner
SION
+20.59%
PRLB
-2.36%
3M
SION
+8.64%
Winner
PRLB
+32.25%
6M
SION
+12.19%
Winner
PRLB
+48.78%
1Y
Winner
SION
+110.78%
PRLB
+87.58%
5Y(CAGR)
SION
N/A
PRLB
-3.03%
10Y(CAGR)
SION
N/A
PRLB
+2.93%
Max(CAGR)
Winner
SION
+49.89%
PRLB
+6.98%
SION vs PRLB - Annual Returns (2012 - 2026)
Returns include dividend reinvestment.
| Year | SION | PRLB |
|---|---|---|
| 2026 | +12.19% | +48.78% |
| 2025 | +64.56% | +30.55% |
| 2024 | N/A | +2.87% |
| 2023 | N/A | +53.99% |
| 2022 | N/A | -52.84% |
| 2021 | N/A | -65.82% |
| 2020 | N/A | +51.54% |
| 2019 | N/A | -9.00% |
| 2018 | N/A | +8.61% |
| 2017 | N/A | +95.08% |
| 2016 | N/A | -18.78% |
| 2015 | N/A | -5.85% |
| 2014 | N/A | -4.17% |
| 2013 | N/A | +81.95% |
| 2012 | N/A | +35.93% |
SION vs PRLB Drawdown Comparison
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The maximum drawdown for PRLB was -91.22%, occurring on Nov 9, 2022. This drawdown has not yet recovered.
The current SION drawdown is -4.27%. The current PRLB drawdown is -69.62%.
| Rank | SION | PRLB |
|---|---|---|
| #1 | -69.36% Feb 7, 2025 - Aug 26, 2025 | -91.22% Jan 27, 2021 - Nov 9, 2022 |
| #2 | -27.07% May 11, 2026 - Jun 8, 2026 | -60.84% Sep 14, 2018 - Dec 22, 2020 |
| #3 | -23.74% Feb 3, 2026 - Apr 15, 2026 | -49.77% Oct 24, 2013 - Oct 26, 2017 |
| #4 | -19.06% Oct 21, 2025 - Nov 21, 2025 | -27.76% Aug 1, 2012 - Jan 15, 2013 |
| #5 | -18.12% Nov 24, 2025 - Feb 3, 2026 | -25.59% May 1, 2012 - Aug 1, 2012 |
| #6 | -17.26% Apr 16, 2026 - May 11, 2026 | -20.25% Dec 23, 2020 - Jan 20, 2021 |
| #7 | -15.94% Aug 28, 2025 - Sep 22, 2025 | -15.54% Feb 13, 2013 - May 3, 2013 |
| #8 | -5.53% Oct 3, 2025 - Oct 15, 2025 | -14.52% Apr 3, 2012 - Apr 27, 2012 |
| #9 | -3.56% Sep 29, 2025 - Oct 3, 2025 | -13.79% Jun 18, 2018 - Jul 25, 2018 |
| #10 | -2.41% Oct 16, 2025 - Oct 21, 2025 | -12.87% May 10, 2013 - Jun 17, 2013 |
| #11 | -0.36% Aug 26, 2025 - Aug 28, 2025 | -11.38% Feb 29, 2012 - Mar 9, 2012 |
| #12 | N/A | -11.15% Oct 4, 2013 - Oct 17, 2013 |
| #13 | N/A | -10.89% Jul 25, 2018 - Aug 20, 2018 |
| #14 | N/A | -10.75% Jan 18, 2013 - Feb 13, 2013 |
| #15 | N/A | -10.25% Mar 20, 2018 - Apr 17, 2018 |
Correlation
Correlation between SION and PRLB is 0.82 which considered as a strong positive correlation - the stocks tend to move together.
0.82
-101
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