SEPN vs PRGS

Comparison between Septerna Inc (SEPN, Company) and Progress Software Corp (PRGS, Company).

SEPN is from the Healthcare sector, while PRGS is from the Technology sector.

SEPN vs PRGS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SEPN(COMPANY)	PRGS(COMPANY)
Market Cap	$1.74B	$1.75B
Max Drawdown	81.47%	64.10%
Sharpe Ratio	2.10	0.12
5Y Beta	1.27	0.62
Industry	Biotechnology	Software - Infrastructure
P/E Ratio	-48.08	20.00
Forward P/E	107.53	6.80
PEG Ratio	N/A	0.35
5Y Dividends CAGR	N/A	2.86%
5Y EPS CAGR	N/A	4.80%
Debt to Equity	0.00%	255.32%
Free Cash Flow Yield	6.14%	17.49%
P/S Ratio	24.18	1.73
P/B Ratio	4.11	3.29

Market Cap

SEPN

$1.74B

Winner

PRGS

$1.75B

Max Drawdown

SEPN

81.47%

Winner

PRGS

64.10%

Sharpe Ratio

Winner

SEPN

2.10

PRGS

0.12

5Y Beta

SEPN

1.27

Winner

PRGS

0.62

Industry

SEPN

Biotechnology

PRGS

Software - Infrastructure

P/E Ratio

Winner

SEPN

-48.08

PRGS

20.00

Forward P/E

SEPN

107.53

Winner

PRGS

6.80

PEG Ratio

SEPN

N/A

PRGS

0.35

5Y Dividends CAGR

SEPN

N/A

PRGS

2.86%

5Y EPS CAGR

SEPN

N/A

PRGS

4.80%

Debt to Equity

Winner

SEPN

0.00%

PRGS

255.32%

Free Cash Flow Yield

SEPN

6.14%

Winner

PRGS

17.49%

P/S Ratio

SEPN

24.18

Winner

PRGS

1.73

P/B Ratio

SEPN

4.11

Winner

PRGS

3.29

SEPN vs PRGS - Historical Returns

Returns include dividend reinvestment.

Period	SEPN	PRGS
1 month	+8.37%	+9.26%
3 months	+61.93%	+45.86%
6 months	+52.81%	-0.35%
1 year	+231.88%	-1.79%
5 years(CAGR)	N/A	-0.66%
10 years(CAGR)	N/A	+5.38%
Max(CAGR)	+39.69%	+5.64%

SEPN

+8.37%

Winner

PRGS

+9.26%

Winner

SEPN

+61.93%

PRGS

+45.86%

Winner

SEPN

+52.81%

PRGS

-0.35%

Winner

SEPN

+231.88%

PRGS

-1.79%

5Y(CAGR)

SEPN

N/A

PRGS

-0.66%

10Y(CAGR)

SEPN

N/A

PRGS

+5.38%

Max(CAGR)

Winner

SEPN

+39.69%

PRGS

+5.64%

SEPN vs PRGS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SEPN	PRGS
2026	+38.78%	+4.31%
2025	+30.59%	-33.61%
2024	+7.01%	+21.18%
2023	N/A	+7.83%
2022	N/A	+6.31%
2021	N/A	+10.18%
2020	N/A	+8.81%
2019	N/A	+19.53%
2018	N/A	-16.72%
2017	N/A	+34.92%
2016	N/A	+33.99%
2015	N/A	-10.25%
2014	N/A	+5.79%
2013	N/A	+19.92%
2012	N/A	+6.01%
2011	N/A	-32.87%
2010	N/A	+43.00%
2009	N/A	+47.06%
2008	N/A	-41.90%
2007	N/A	+19.73%
2006	N/A	-3.32%
2005	N/A	+21.80%
2004	N/A	+12.91%
2003	N/A	+55.47%
2002	N/A	-28.85%
2001	N/A	+25.67%
2000	N/A	-46.89%
1999	N/A	+70.01%

SEPN vs PRGS Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for PRGS was -64.10%, occurring on Apr 1, 2026. This drawdown has not yet recovered.

The current SEPN drawdown is -1.77%. The current PRGS drawdown is -38.70%.

Rank	SEPN	PRGS
#1	-81.47% Dec 23, 2024 - Nov 24, 2025	-64.10% Nov 25, 2024 - Apr 1, 2026
#2	-25.18% Feb 24, 2026 - May 28, 2026	-61.44% Dec 28, 1999 - Jun 16, 2005
#3	-21.10% Dec 19, 2025 - Feb 17, 2026	-56.52% Dec 26, 2007 - May 13, 2010
#4	-16.77% Dec 4, 2024 - Dec 23, 2024	-45.30% Feb 14, 2011 - Dec 8, 2016
#5	-16.60% Jul 9, 2026 - Aug 4, 2026	-41.33% Jan 17, 2018 - Sep 24, 2021
#6	-16.19% Nov 7, 2024 - Dec 4, 2024	-36.26% Sep 20, 2005 - May 31, 2007
#7	-13.97% Nov 26, 2025 - Dec 19, 2025	-22.51% May 13, 2010 - Oct 8, 2010
#8	-10.63% Feb 17, 2026 - Feb 24, 2026	-21.14% Nov 16, 2021 - Nov 15, 2022
#9	-10.36% Jun 26, 2026 - Jul 9, 2026	-21.02% Aug 29, 2023 - Sep 25, 2024
#10	-6.45% Oct 25, 2024 - Oct 31, 2024	-19.22% Jun 21, 2007 - Dec 6, 2007
#11	-5.55% Jun 23, 2026 - Jun 26, 2026	-14.70% Dec 27, 2016 - Jul 25, 2017
#12	-4.76% Oct 31, 2024 - Nov 4, 2024	-12.55% Dec 20, 1999 - Dec 28, 1999
#13	-3.65% Jun 18, 2026 - Jun 23, 2026	-12.48% Jun 14, 2023 - Aug 7, 2023
#14	-3.57% May 28, 2026 - Jun 4, 2026	-12.21% Dec 6, 1999 - Dec 15, 1999
#15	-3.45% Nov 4, 2024 - Nov 6, 2024	-9.11% Mar 3, 2023 - May 24, 2023

Correlation

Correlation between SEPN and PRGS is -0.50 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.50

-101