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SEPN vs PGEN

Comparison between Septerna Inc (SEPN, Company) and Precigen Inc (PGEN, Company).

Both SEPN and PGEN are from the Healthcare sector.

SEPN vs PGEN - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
SEPN
$1.37B
Winner
PGEN
$1.37B
Max Drawdown
Winner
SEPN
81.47%
PGEN
99.01%
Sharpe Ratio
Winner
SEPN
2.15
PGEN
1.46
5Y Beta
Winner
SEPN
1.33
PGEN
1.69
Industry
SEPN
Biotechnology
PGEN
Biotechnology
P/E Ratio
Winner
SEPN
-37.80
PGEN
-6.58
Forward P/E
Winner
SEPN
107.53
PGEN
196.08
PEG Ratio
SEPN
N/A
PGEN
-1.20
5Y EPS CAGR
SEPN
N/A
PGEN
-3.77%
Debt to Equity
Winner
SEPN
0.00%
PGEN
462.16%
Free Cash Flow Yield
Winner
SEPN
7.81%
PGEN
-8.52%
P/S Ratio
Winner
SEPN
19.01
PGEN
43.89
P/B Ratio
Winner
SEPN
3.62
PGEN
68.45

SEPN vs PGEN - Historical Returns

Returns include dividend reinvestment.

1M
Winner
SEPN
+44.73%
PGEN
+9.07%
3M
Winner
SEPN
+35.94%
PGEN
+35.67%
6M
Winner
SEPN
+41.31%
PGEN
+20.60%
1Y
Winner
SEPN
+245.34%
PGEN
+192.76%
5Y(CAGR)
SEPN
N/A
PGEN
-9.50%
10Y(CAGR)
SEPN
N/A
PGEN
-15.74%
Max(CAGR)
Winner
SEPN
+37.50%
PGEN
-11.88%

SEPN vs PGEN - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

YearSEPNPGEN
2026+28.48%+3.97%
2025+30.59%+287.04%
2024+7.01%-20.57%
2023N/A-9.46%
2022N/A-61.81%
2021N/A-66.12%
2020N/A+72.59%
2019N/A-23.36%
2018N/A-51.45%
2017N/A-52.67%
2016N/A-16.70%
2015N/A+24.14%
2014N/A+15.96%
2013N/A-3.76%

SEPN vs PGEN Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for PGEN was -99.00%, occurring on Dec 16, 2024. This drawdown has not yet recovered.

The current PGEN drawdown is -93.40%.

RankSEPNPGEN
#1-81.47%
Dec 23, 2024 - Nov 24, 2025
-99.00%
Aug 5, 2015 - Dec 16, 2024
#2-25.18%
Feb 24, 2026 - May 28, 2026
-58.45%
Jan 17, 2014 - Jan 14, 2015
#3-21.10%
Dec 19, 2025 - Feb 17, 2026
-40.57%
Aug 12, 2013 - Jan 10, 2014
#4-16.77%
Dec 4, 2024 - Dec 23, 2024
-26.70%
Jan 14, 2015 - Feb 12, 2015
#5-16.19%
Nov 7, 2024 - Dec 4, 2024
-22.81%
Mar 6, 2015 - Jun 17, 2015
#6-13.97%
Nov 26, 2025 - Dec 19, 2025
-11.24%
Jun 22, 2015 - Jul 15, 2015
#7-10.63%
Feb 17, 2026 - Feb 24, 2026
-7.34%
Jul 22, 2015 - Jul 28, 2015
#8-6.45%
Oct 25, 2024 - Oct 31, 2024
-6.29%
Feb 26, 2015 - Mar 3, 2015
#9-4.76%
Oct 31, 2024 - Nov 4, 2024
-4.31%
Feb 20, 2015 - Feb 25, 2015
#10-3.57%
May 28, 2026 - Jun 4, 2026
-3.78%
Jan 10, 2014 - Jan 14, 2014
#11-3.45%
Nov 4, 2024 - Nov 6, 2024
-2.04%
Jul 20, 2015 - Jul 22, 2015
#12-3.06%
Jun 4, 2026 - Jun 11, 2026
-1.38%
Feb 17, 2015 - Feb 19, 2015
#13-1.89%
Nov 24, 2025 - Nov 26, 2025
-0.60%
Jun 17, 2015 - Jun 19, 2015
#14N/A-0.08%
Mar 3, 2015 - Mar 5, 2015
#15N/A-0.08%
Jul 31, 2015 - Aug 4, 2015

Correlation

Correlation between SEPN and PGEN is 0.56 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.56
-101

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