SEPN vs OLPX

Comparison between Septerna Inc (SEPN, Company) and Olaplex Holdings Inc (OLPX, Company).

SEPN is from the Healthcare sector, while OLPX is from the Consumer Cyclical sector.

SEPN vs OLPX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SEPN(COMPANY)	OLPX(COMPANY)
Market Cap	$1.37B	$1.37B
Max Drawdown	81.47%	96.57%
Sharpe Ratio	2.15	0.84
5Y Beta	1.33	1.08
Industry	Biotechnology	Specialty Retail
P/E Ratio	-37.80	-91.05
Forward P/E	107.53	20.37
Debt to Equity	0.00%	40.15%
Free Cash Flow Yield	7.81%	5.01%
P/S Ratio	19.01	3.22
P/B Ratio	3.62	1.56

Market Cap

SEPN

$1.37B

Winner

OLPX

$1.37B

Max Drawdown

Winner

SEPN

81.47%

OLPX

96.57%

Sharpe Ratio

Winner

SEPN

2.15

OLPX

0.84

5Y Beta

SEPN

1.33

Winner

OLPX

1.08

Industry

SEPN

Biotechnology

OLPX

Specialty Retail

P/E Ratio

SEPN

-37.80

Winner

OLPX

-91.05

Forward P/E

SEPN

107.53

Winner

OLPX

20.37

Debt to Equity

Winner

SEPN

0.00%

OLPX

40.15%

Free Cash Flow Yield

Winner

SEPN

7.81%

OLPX

5.01%

P/S Ratio

SEPN

19.01

Winner

OLPX

3.22

P/B Ratio

SEPN

3.62

Winner

OLPX

1.56

SEPN vs OLPX - Historical Returns

Returns include dividend reinvestment.

Period	SEPN	OLPX
1 month	+44.73%	+0.00%
3 months	+35.94%	+64.52%
6 months	+41.31%	+60.63%
1 year	+245.34%	+52.24%
5 years(CAGR)	N/A	-41.09%
Max(CAGR)	+37.50%	-41.09%

Winner

SEPN

+44.73%

OLPX

+0.00%

SEPN

+35.94%

Winner

OLPX

+64.52%

SEPN

+41.31%

Winner

OLPX

+60.63%

Winner

SEPN

+245.34%

OLPX

+52.24%

5Y(CAGR)

SEPN

N/A

OLPX

-41.09%

Max(CAGR)

Winner

SEPN

+37.50%

OLPX

-41.09%

SEPN vs OLPX - Annual Returns (2021 - 2026)

Returns include dividend reinvestment.

Year	SEPN	OLPX
2026	+28.48%	+51.11%
2025	+30.59%	-20.71%
2024	+7.01%	-30.80%
2023	N/A	-50.97%
2022	N/A	-82.28%
2021	N/A	+18.90%

SEPN vs OLPX Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for OLPX was -96.57%, occurring on Nov 18, 2025. This drawdown has not yet recovered.

The current OLPX drawdown is -93.06%.

Rank	SEPN	OLPX
#1	-81.47% Dec 23, 2024 - Nov 24, 2025	-96.57% Jan 3, 2022 - Nov 18, 2025
#2	-25.18% Feb 24, 2026 - May 28, 2026	-17.41% Oct 22, 2021 - Dec 31, 2021
#3	-21.10% Dec 19, 2025 - Feb 17, 2026	-7.15% Oct 5, 2021 - Oct 20, 2021
#4	-16.77% Dec 4, 2024 - Dec 23, 2024	-6.53% Sep 30, 2021 - Oct 5, 2021
#5	-16.19% Nov 7, 2024 - Dec 4, 2024	N/A
#6	-13.97% Nov 26, 2025 - Dec 19, 2025	N/A
#7	-10.63% Feb 17, 2026 - Feb 24, 2026	N/A
#8	-6.45% Oct 25, 2024 - Oct 31, 2024	N/A
#9	-4.76% Oct 31, 2024 - Nov 4, 2024	N/A
#10	-3.57% May 28, 2026 - Jun 4, 2026	N/A
#11	-3.45% Nov 4, 2024 - Nov 6, 2024	N/A
#12	-3.06% Jun 4, 2026 - Jun 11, 2026	N/A
#13	-1.89% Nov 24, 2025 - Nov 26, 2025	N/A