SEPN vs CDNA
Comparison between Septerna Inc (SEPN, Company) and Caredx Inc (CDNA, Company).
Both SEPN and CDNA are from the Healthcare sector.
SEPN vs CDNA - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
SEPN
$1.53B
CDNA
$1.53B
Max Drawdown
Winner
SEPN
81.47%
CDNA
94.87%
Sharpe Ratio
SEPN
1.78
Winner
CDNA
1.94
5Y Beta
Winner
SEPN
1.24
CDNA
1.27
Industry
SEPN
Biotechnology
CDNA
Diagnostics & Research
P/E Ratio
SEPN
-42.26
Winner
CDNA
-192.80
Forward P/E
SEPN
107.53
Winner
CDNA
94.34
PEG Ratio
SEPN
N/A
CDNA
-0.12
5Y EPS CAGR
SEPN
N/A
CDNA
-10.97%
Debt to Equity
SEPN
0.00%
CDNA
0.00%
Free Cash Flow Yield
Winner
SEPN
6.99%
CDNA
4.53%
P/S Ratio
SEPN
21.25
Winner
CDNA
3.62
P/B Ratio
Winner
SEPN
4.11
CDNA
4.74
SEPN vs CDNA - Historical Returns
Returns include dividend reinvestment.
1M
SEPN
-3.36%
Winner
CDNA
+53.85%
3M
SEPN
+30.54%
Winner
CDNA
+85.91%
6M
SEPN
+27.82%
Winner
CDNA
+85.02%
1Y
SEPN
+173.60%
Winner
CDNA
+202.27%
5Y(CAGR)
SEPN
N/A
CDNA
-14.54%
10Y(CAGR)
SEPN
N/A
CDNA
+23.19%
Max(CAGR)
Winner
SEPN
+29.86%
CDNA
+12.82%
SEPN vs CDNA - Annual Returns (2014 - 2026)
Returns include dividend reinvestment.
| Year | SEPN | CDNA |
|---|---|---|
| 2026 | +20.37% | +101.36% |
| 2025 | +30.59% | -12.45% |
| 2024 | +7.01% | +79.31% |
| 2023 | N/A | +8.11% |
| 2022 | N/A | -75.52% |
| 2021 | N/A | -36.38% |
| 2020 | N/A | +242.55% |
| 2019 | N/A | -10.05% |
| 2018 | N/A | +256.60% |
| 2017 | N/A | +219.13% |
| 2016 | N/A | -56.94% |
| 2015 | N/A | -11.42% |
| 2014 | N/A | -19.89% |
SEPN vs CDNA Drawdown Comparison
The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.
The maximum drawdown for CDNA was -94.87%, occurring on Oct 25, 2023. This drawdown has not yet recovered.
The current SEPN drawdown is -10.99%. The current CDNA drawdown is -59.69%.
| Rank | SEPN | CDNA |
|---|---|---|
| #1 | -81.47% Dec 23, 2024 - Nov 24, 2025 | -94.87% Jan 20, 2021 - Oct 25, 2023 |
| #2 | -25.18% Feb 24, 2026 - May 28, 2026 | -92.75% Sep 8, 2014 - May 9, 2018 |
| #3 | -21.10% Dec 19, 2025 - Feb 17, 2026 | -65.22% Jul 11, 2019 - Oct 1, 2020 |
| #4 | -16.77% Dec 4, 2024 - Dec 23, 2024 | -34.25% Mar 21, 2019 - Jun 19, 2019 |
| #5 | -16.60% Jul 9, 2026 - Jul 16, 2026 | -33.74% Dec 3, 2018 - Feb 27, 2019 |
| #6 | -16.19% Nov 7, 2024 - Dec 4, 2024 | -24.19% Sep 28, 2018 - Nov 15, 2018 |
| #7 | -13.97% Nov 26, 2025 - Dec 19, 2025 | -24.19% Jun 15, 2018 - Aug 10, 2018 |
| #8 | -10.63% Feb 17, 2026 - Feb 24, 2026 | -16.33% Nov 16, 2018 - Dec 3, 2018 |
| #9 | -10.36% Jun 26, 2026 - Jul 9, 2026 | -13.93% Jun 19, 2019 - Jul 11, 2019 |
| #10 | -6.45% Oct 25, 2024 - Oct 31, 2024 | -11.11% Oct 9, 2020 - Nov 5, 2020 |
| #11 | -5.55% Jun 23, 2026 - Jun 26, 2026 | -9.06% Nov 20, 2020 - Dec 3, 2020 |
| #12 | -4.76% Oct 31, 2024 - Nov 4, 2024 | -7.75% Jul 30, 2014 - Aug 11, 2014 |
| #13 | -3.65% Jun 18, 2026 - Jun 23, 2026 | -7.46% Sep 10, 2018 - Sep 18, 2018 |
| #14 | -3.57% May 28, 2026 - Jun 4, 2026 | -7.26% Dec 22, 2020 - Jan 8, 2021 |
| #15 | -3.45% Nov 4, 2024 - Nov 6, 2024 | -6.71% Mar 14, 2019 - Mar 21, 2019 |
Correlation
Correlation between SEPN and CDNA is 0.54 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.54
-101
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