SBIO vs TRFM
Comparison between ALPS MEDICAL BREAKTHROUGHS ETF (SBIO, ETF) and AAM TRANSFORMERS ETF (TRFM, ETF).
SBIO vs TRFM - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
SBIO
$156M
Winner
TRFM
$156M
Expense Ratio
SBIO
0.50%
Winner
TRFM
0.49%
Max Drawdown
SBIO
63.06%
Winner
TRFM
28.40%
Sharpe Ratio
Winner
SBIO
1.69
TRFM
1.48
5Y Beta
Winner
SBIO
1.03
TRFM
1.44
P/E Ratio
Winner
SBIO
-13.78
TRFM
74.13
Forward P/E
SBIO
N/A
TRFM
30.06
5Y Dividends CAGR
SBIO
9.24%
TRFM
N/A
5Y EPS CAGR
SBIO
N/A
TRFM
16.17%
Debt to Equity
SBIO
4.92%
TRFM
N/A
P/S Ratio
SBIO
7.34
Winner
TRFM
1.70
P/B Ratio
Winner
SBIO
4.16
TRFM
6.43
SBIO vs TRFM - Holdings Comparison
SBIO and TRFM have 1 common holdings. Overlap is -1.49%
SBIO's top 25 holdings weight is 63.20%. TRFM's top 25 holdings weight is 23.55%.
| Rank | SBIO | TRFM |
|---|---|---|
| #1 | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 4.26% | OTHER ASSETS AND LIABILITIES (n/a) - 1.56% |
| #2 | ALKERMES PLC (ALKS) - 4.02% | SANDISK CORP ORDINARY SHARES (SNDK) - 1.34% |
| #3 | CELCUITY INC (CELC) - 4.01% | ADVANCED MICRO DEVICES INC (AMD) - 1.32% |
| #4 | MIRUM PHARMACEUTICALS INC (MIRM) - 3.86% | MICRON TECHNOLOGY INC (MU) - 1.11% |
| #5 | SPYRE THERAPEUTICS INC (SYRE) - 3.74% | SEAGATE TECHNOLOGY HOLDINGS PLC (STX) - 1.10% |
| #6 | CG ONCOLOGY INC (CGON) - 3.38% | BLOOM ENERGY CORP CLASS A (BE) - 1.01% |
| #7 | APOGEE THERAPEUTICS INC (APGE) - 3.00% | MARVELL TECHNOLOGY INC (MRVL) - 1.00% |
| #8 | XENON PHARMACEUTICALS INC (XENE) - 2.90% | WESTERN DIGITAL CORP (WDC) - 0.99% |
| #9 | NEWAMSTERDAM PHARMA CO NV (NAMS) - 2.68% | ROCKET LAB CORP (RKLB) - 0.99% |
| #10 | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 2.64% | CIENA CORP (CIEN) - 0.94% |
| #11 | CRINETICS PHARMACEUTICALS INC (CRNX) - 2.49% | TEXAS INSTRUMENTS INC (TXN) - 0.94% |
| #12 | DIANTHUS THERAPEUTICS INC (DNTH) - 2.49% | DATADOG INC CLASS A (DDOG) - 0.88% |
| #13 | ACADIA PHARMACEUTICALS INC (ACAD) - 2.34% | n/a (DELL) - 0.86% |
| #14 | EDGEWISE THERAPEUTICS INC (EWTX) - 2.33% | LAM RESEARCH CORP (LRCX) - 0.84% |
| #15 | VIKING THERAPEUTICS INC (VKTX) - 2.30% | LUMENTUM HOLDINGS INC (LITE) - 0.84% |
| #16 | DENALI THERAPEUTICS INC (DNLI) - 1.99% | COHERENT CORP (COHR) - 0.81% |
| #17 | ORUKA THERAPEUTICS INC (ORKA) - 1.85% | PALO ALTO NETWORKS INC (PANW) - 0.80% |
| #18 | STRUCTURE THERAPEUTICS INC ADR (GPCR) - 1.81% | ALPHABET INC CLASS A (GOOGL) - 0.80% |
| #19 | n/a (TARS) - 1.68% | ANALOG DEVICES INC (ADI) - 0.80% |
| #20 | DISC MEDICINE INC ORDINARY SHARES (IRON) - 1.68% | KLA CORP (KLAC) - 0.78% |
| #21 | IDEAYA BIOSCIENCES INC (IDYA) - 1.67% | BROADCOM INC (AVGO) - 0.77% |
| #22 | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.64% | APPLIED MATERIALS INC (AMAT) - 0.77% |
| #23 | VERA THERAPEUTICS INC CLASS A (VERA) - 1.58% | CORNING INC (GLW) - 0.77% |
| #24 | MINERALYS THERAPEUTICS INC (MLYS) - 1.53% | GE VERNOVA INC (GEV) - 0.77% |
| #25 | CELLDEX THERAPEUTICS INC (CLDX) - 1.33% | MONOLITHIC POWER SYSTEMS INC (MPWR) - 0.76% |
| Total Holdings | 86 | 262 |
SBIO vs TRFM - Historical Returns
Returns include dividend reinvestment.
1M
SBIO
-8.63%
Winner
TRFM
+3.28%
3M
SBIO
+2.25%
Winner
TRFM
+20.12%
6M
SBIO
+0.14%
Winner
TRFM
+19.01%
1Y
Winner
SBIO
+62.88%
TRFM
+42.62%
5Y(CAGR)
SBIO
+2.48%
TRFM
N/A
10Y(CAGR)
SBIO
+7.68%
TRFM
N/A
Max(CAGR)
SBIO
+7.19%
Winner
TRFM
+25.94%
SBIO vs TRFM - Annual Returns (2014 - 2026)
Returns include dividend reinvestment.
| Year | SBIO | TRFM |
|---|---|---|
| 2026 | +0.72% | +19.40% |
| 2025 | +53.69% | +24.92% |
| 2024 | +4.25% | +23.50% |
| 2023 | +11.05% | +45.11% |
| 2022 | -30.19% | -7.38% |
| 2021 | -17.90% | N/A |
| 2020 | +23.09% | N/A |
| 2019 | +47.58% | N/A |
| 2018 | -13.24% | N/A |
| 2017 | +44.12% | N/A |
| 2016 | -25.20% | N/A |
| 2015 | +26.42% | N/A |
| 2014 | +0.00% | N/A |
SBIO vs TRFM Drawdown Comparison
The maximum drawdown for SBIO was -63.06%, occurring on Oct 27, 2023. This drawdown has not yet recovered.
The maximum drawdown for TRFM was -28.40%, occurring on Apr 8, 2025. Recovery took 87 trading sessions.
The current SBIO drawdown is -17.62%. The current TRFM drawdown is -7.86%.
| Rank | SBIO | TRFM |
|---|---|---|
| #1 | -63.06% Feb 8, 2021 - Oct 27, 2023 | -28.40% Feb 18, 2025 - Jun 24, 2025 |
| #2 | -49.69% Jul 17, 2015 - Jun 6, 2018 | -26.91% Aug 15, 2022 - Jun 13, 2023 |
| #3 | -39.30% Dec 24, 2019 - Jun 23, 2020 | -18.43% Jul 31, 2023 - Dec 13, 2023 |
| #4 | -32.42% Sep 28, 2018 - Nov 25, 2019 | -16.07% Jul 16, 2024 - Oct 11, 2024 |
| #5 | -13.78% Apr 23, 2015 - May 20, 2015 | -12.99% Jan 28, 2026 - Apr 13, 2026 |
| #6 | -13.03% Jun 23, 2020 - Oct 7, 2020 | -12.52% Oct 29, 2025 - Jan 28, 2026 |
| #7 | -11.31% Mar 19, 2015 - Apr 13, 2015 | -8.57% Mar 7, 2024 - May 15, 2024 |
| #8 | -6.72% Jun 6, 2018 - Sep 28, 2018 | -7.86% Jun 2, 2026 - Jun 5, 2026 |
| #9 | -6.30% Jan 27, 2015 - Feb 17, 2015 | -7.84% Jul 21, 2022 - Aug 2, 2022 |
| #10 | -6.29% Jun 22, 2015 - Jul 13, 2015 | -6.84% Dec 6, 2024 - Jan 22, 2025 |
| #11 | -6.19% Dec 22, 2020 - Jan 7, 2021 | -5.93% Dec 28, 2023 - Feb 7, 2024 |
| #12 | -4.88% Oct 13, 2020 - Oct 27, 2020 | -5.66% Jun 15, 2023 - Jul 11, 2023 |
| #13 | -3.81% Jan 14, 2015 - Jan 20, 2015 | -4.95% May 11, 2026 - May 22, 2026 |
| #14 | -3.39% Oct 27, 2020 - Nov 4, 2020 | -4.83% Jan 23, 2025 - Feb 10, 2025 |
| #15 | -3.31% Jan 26, 2021 - Feb 1, 2021 | -4.52% Feb 15, 2024 - Mar 1, 2024 |
Correlation
Correlation between SBIO and TRFM is 0.85 which considered as a strong positive correlation - the stocks tend to move together.
0.85
-101
Dividend Comparison (2017 - 2025)
SBIO vs TRFM dividend yield comparison.
| Year | SBIO | TRFM |
|---|---|---|
| 2025 | 0.00% | 0.17% |
| 2024 | 3.55% | 0.00% |
| 2023 | 0.22% | 0.00% |
| 2019 | 0.04% | 0.00% |
| 2018 | 2.79% | 0.00% |
| 2017 | 1.77% | 0.00% |
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