SBIO vs MVV
Comparison between ALPS MEDICAL BREAKTHROUGHS ETF (SBIO, ETF) and PROSHARES ULTRA MIDCAP400 (MVV, ETF).
5-Year PerformanceMVV has outperformed SBIO, delivering a return of +5.9% compared to +2.5%
SBIO vs MVV - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
Winner
SBIO
$156M
MVV
$155M
Expense Ratio
SBIO
0.50%
MVV
N/A
Max Drawdown
Winner
SBIO
63.06%
MVV
86.35%
Sharpe Ratio
Winner
SBIO
1.69
MVV
1.14
5Y Beta
Winner
SBIO
1.03
MVV
2.01
P/E Ratio
Winner
SBIO
-13.78
MVV
24.91
Forward P/E
SBIO
N/A
MVV
16.09
5Y Dividends CAGR
SBIO
9.24%
Winner
MVV
34.85%
Debt to Equity
Winner
SBIO
4.92%
MVV
48.36%
P/S Ratio
SBIO
7.34
Winner
MVV
1.53
P/B Ratio
SBIO
4.16
Winner
MVV
2.56
SBIO vs MVV - Holdings Comparison
SBIO and MVV have 1 common holdings. Overlap is -0.80%
SBIO's top 25 holdings weight is 63.20%. MVV's top 25 holdings weight is 33.65%.
| Rank | SBIO | MVV |
|---|---|---|
| #1 | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 4.26% | CASH (n/a) - 8.76% |
| #2 | ALKERMES PLC (ALKS) - 4.02% | S&P MIDCAP 400 INDEX SWAP (n/a) - 7.68% |
| #3 | CELCUITY INC (CELC) - 4.01% | PROSHARES GENIUS MONEY MARKET ETF (IQMM) - 3.13% |
| #4 | MIRUM PHARMACEUTICALS INC (MIRM) - 3.86% | CTE PROSHARES TRUST M (n/a) - 3.06% |
| #5 | SPYRE THERAPEUTICS INC (SYRE) - 3.74% | E-MINI S&P MIDCAP 400 FUTURE JUNE 26 (n/a) - 1.42% |
| #6 | CG ONCOLOGY INC (CGON) - 3.38% | FLEX LTD (FLEX) - 1.14% |
| #7 | APOGEE THERAPEUTICS INC (APGE) - 3.00% | TECHNIPFMC PLC (n/a) - 0.62% |
| #8 | XENON PHARMACEUTICALS INC (XENE) - 2.90% | TWILIO INC CLASS A (TWLO) - 0.62% |
| #9 | NEWAMSTERDAM PHARMA CO NV (NAMS) - 2.68% | CURTISS-WRIGHT CORP (CW) - 0.60% |
| #10 | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 2.64% | EVERPURE INC CLASS A (P) - 0.60% |
| #11 | CRINETICS PHARMACEUTICALS INC (CRNX) - 2.49% | NVENT ELECTRIC PLC (NVT) - 0.59% |
| #12 | DIANTHUS THERAPEUTICS INC (DNTH) - 2.49% | MACOM TECHNOLOGY SOLUTIONS HOLDINGS INC (MTSI) - 0.57% |
| #13 | ACADIA PHARMACEUTICALS INC (ACAD) - 2.34% | UNITED THERAPEUTICS CORP (UTHR) - 0.54% |
| #14 | EDGEWISE THERAPEUTICS INC (EWTX) - 2.33% | FABRINET (FN) - 0.53% |
| #15 | VIKING THERAPEUTICS INC (VKTX) - 2.30% | XPO INC (XPO) - 0.53% |
| #16 | DENALI THERAPEUTICS INC (DNLI) - 1.99% | STERLING INFRASTRUCTURE INC (STRL) - 0.52% |
| #17 | ORUKA THERAPEUTICS INC (ORKA) - 1.85% | JAZZ PHARMACEUTICALS PLC (JAZZ) - 0.31% |
| #18 | STRUCTURE THERAPEUTICS INC ADR (GPCR) - 1.81% | CLEAN HARBORS INC (CLH) - 0.31% |
| #19 | n/a (TARS) - 1.68% | PERMIAN RESOURCES CORP CLASS A (PR) - 0.31% |
| #20 | DISC MEDICINE INC ORDINARY SHARES (IRON) - 1.68% | BORGWARNER INC (BWA) - 0.31% |
| #21 | IDEAYA BIOSCIENCES INC (IDYA) - 1.67% | ARAMARK (ARMK) - 0.30% |
| #22 | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.64% | REGAL REXNORD CORP (RRX) - 0.30% |
| #23 | VERA THERAPEUTICS INC CLASS A (VERA) - 1.58% | JONES LANG LASALLE INC (JLL) - 0.30% |
| #24 | MINERALYS THERAPEUTICS INC (MLYS) - 1.53% | CARLISLE COMPANIES INC (CSL) - 0.30% |
| #25 | CELLDEX THERAPEUTICS INC (CLDX) - 1.33% | REINSURANCE GROUP OF AMERICA INC (RGA) - 0.30% |
| Total Holdings | 86 | 366 |
SBIO vs MVV - Historical Returns
Returns include dividend reinvestment.
1M
SBIO
-8.63%
Winner
MVV
+1.33%
3M
SBIO
+2.25%
Winner
MVV
+10.20%
6M
SBIO
+0.14%
Winner
MVV
+20.56%
1Y
Winner
SBIO
+62.88%
MVV
+41.41%
5Y(CAGR)
SBIO
+2.48%
Winner
MVV
+5.91%
10Y(CAGR)
SBIO
+7.68%
Winner
MVV
+13.11%
Max(CAGR)
SBIO
+7.19%
Winner
MVV
+11.27%
SBIO vs MVV - Annual Returns (2006 - 2026)
Returns include dividend reinvestment.
| Year | SBIO | MVV |
|---|---|---|
| 2026 | +0.72% | +18.84% |
| 2025 | +53.69% | +4.14% |
| 2024 | +4.25% | +18.77% |
| 2023 | +11.05% | +23.70% |
| 2022 | -30.19% | -32.28% |
| 2021 | -17.90% | +53.56% |
| 2020 | +23.09% | +5.89% |
| 2019 | +47.58% | +50.98% |
| 2018 | -13.24% | -26.72% |
| 2017 | +44.12% | +29.39% |
| 2016 | -25.20% | +43.69% |
| 2015 | +26.42% | -7.38% |
| 2014 | +0.00% | +18.60% |
| 2013 | N/A | +62.98% |
| 2012 | N/A | +31.00% |
| 2011 | N/A | -14.88% |
| 2010 | N/A | +47.37% |
| 2009 | N/A | +60.56% |
| 2008 | N/A | -67.39% |
| 2007 | N/A | +3.93% |
| 2006 | N/A | +14.49% |
SBIO vs MVV Drawdown Comparison
The maximum drawdown for SBIO was -63.06%, occurring on Oct 27, 2023. This drawdown has not yet recovered.
The maximum drawdown for MVV was -85.56%, occurring on Mar 9, 2009. Recovery took 1487 trading sessions.
The current SBIO drawdown is -17.62%. The current MVV drawdown is -3.94%.
| Rank | SBIO | MVV |
|---|---|---|
| #1 | -63.06% Feb 8, 2021 - Oct 27, 2023 | -85.56% Jun 4, 2007 - Apr 30, 2013 |
| #2 | -49.69% Jul 17, 2015 - Jun 6, 2018 | -69.19% Feb 20, 2020 - Dec 15, 2020 |
| #3 | -39.30% Dec 24, 2019 - Jun 23, 2020 | -45.52% Nov 16, 2021 - Nov 6, 2024 |
| #4 | -32.42% Sep 28, 2018 - Nov 25, 2019 | -44.80% Nov 25, 2024 - Feb 6, 2026 |
| #5 | -13.78% Apr 23, 2015 - May 20, 2015 | -42.33% Aug 29, 2018 - Jan 16, 2020 |
| #6 | -13.03% Jun 23, 2020 - Oct 7, 2020 | -36.76% Jun 23, 2015 - Aug 5, 2016 |
| #7 | -11.31% Mar 19, 2015 - Apr 13, 2015 | -20.79% Jul 1, 2014 - Nov 24, 2014 |
| #8 | -6.72% Jun 6, 2018 - Sep 28, 2018 | -18.80% Jan 26, 2018 - Jul 9, 2018 |
| #9 | -6.30% Jan 27, 2015 - Feb 17, 2015 | -17.68% Feb 20, 2026 - Apr 17, 2026 |
| #10 | -6.29% Jun 22, 2015 - Jul 13, 2015 | -14.87% Jul 3, 2006 - Oct 12, 2006 |
| #11 | -6.19% Dec 22, 2020 - Jan 7, 2021 | -14.25% May 7, 2021 - Oct 20, 2021 |
| #12 | -4.88% Oct 13, 2020 - Oct 27, 2020 | -14.24% May 21, 2013 - Jul 11, 2013 |
| #13 | -3.81% Jan 14, 2015 - Jan 20, 2015 | -14.10% Feb 22, 2007 - Apr 16, 2007 |
| #14 | -3.39% Oct 27, 2020 - Nov 4, 2020 | -13.90% Jan 22, 2014 - Feb 26, 2014 |
| #15 | -3.31% Jan 26, 2021 - Feb 1, 2021 | -12.88% Sep 7, 2016 - Nov 14, 2016 |
Correlation
Correlation between SBIO and MVV is 0.62 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.62
-101
Dividend Comparison (2006 - 2026)
SBIO vs MVV dividend yield comparison.
| Year | SBIO | MVV |
|---|---|---|
| 2026 | 0.00% | 0.13% |
| 2025 | 0.00% | 0.77% |
| 2024 | 3.55% | 0.39% |
| 2023 | 0.22% | 0.77% |
| 2022 | 0.00% | 0.93% |
| 2021 | 0.00% | 0.16% |
| 2020 | 0.00% | 0.29% |
| 2019 | 0.04% | 0.62% |
| 2018 | 2.79% | 0.62% |
| 2017 | 1.77% | 0.21% |
| 2016 | 0.00% | 0.43% |
| 2015 | 0.00% | 0.17% |
| 2012 | 0.00% | 0.06% |
| 2010 | 0.00% | 0.07% |
| 2009 | 0.00% | 0.34% |
| 2008 | 0.00% | 1.51% |
| 2007 | 0.00% | 5.74% |
| 2006 | 0.00% | 5.53% |
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