QSI vs KPTI

Comparison between Quantum-Si Incorporated - Class A (QSI, Company) and Karyopharm Therapeutics Inc (KPTI, Company).

Both QSI and KPTI are from the Healthcare sector.

5-Year PerformanceQSI has outperformed KPTI, delivering a return of -37.3% compared to -42.8%

QSI vs KPTI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	QSI(COMPANY)	KPTI(COMPANY)
Market Cap	$205M	$205M
Max Drawdown	97.18%	99.50%
Sharpe Ratio	-0.24	1.24
5Y Beta	2.33	0.86
Industry	Medical Devices	Biotechnology
P/E Ratio	-1.78	-0.62
PEG Ratio	N/A	-0.01
5Y EPS CAGR	N/A	-18.43%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-46.72%	-28.78%
P/S Ratio	110.24	1.30
P/B Ratio	1.03	12.05

Market Cap

QSI

$205M

Winner

KPTI

$205M

Max Drawdown

Winner

QSI

97.18%

KPTI

99.50%

Sharpe Ratio

QSI

-0.24

Winner

KPTI

1.24

5Y Beta

QSI

2.33

Winner

KPTI

0.86

Industry

QSI

Medical Devices

KPTI

Biotechnology

P/E Ratio

Winner

QSI

-1.78

KPTI

-0.62

PEG Ratio

QSI

N/A

KPTI

-0.01

5Y EPS CAGR

QSI

N/A

KPTI

-18.43%

Debt to Equity

QSI

0.00%

KPTI

0.00%

Free Cash Flow Yield

QSI

-46.72%

Winner

KPTI

-28.78%

P/S Ratio

QSI

110.24

Winner

KPTI

1.30

P/B Ratio

Winner

QSI

1.03

KPTI

12.05

QSI vs KPTI - Historical Returns

Returns include dividend reinvestment.

Period	QSI	KPTI
1 month	+0.23%	+6.56%
3 months	-3.00%	+20.25%
6 months	-26.61%	+36.69%
1 year	-47.11%	+117.89%
5 years(CAGR)	-37.26%	-42.76%
10 years(CAGR)	N/A	-22.75%
Max(CAGR)	-34.33%	-22.63%

QSI

+0.23%

Winner

KPTI

+6.56%

QSI

-3.00%

Winner

KPTI

+20.25%

QSI

-26.61%

Winner

KPTI

+36.69%

QSI

-47.11%

Winner

KPTI

+117.89%

5Y(CAGR)

Winner

QSI

-37.26%

KPTI

-42.76%

10Y(CAGR)

QSI

N/A

KPTI

-22.75%

Max(CAGR)

QSI

-34.33%

Winner

KPTI

-22.63%

QSI vs KPTI - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	QSI	KPTI
2026	-18.39%	+32.13%
2025	-74.18%	-39.54%
2024	+33.00%	-24.96%
2023	+9.24%	-73.47%
2022	-77.74%	-52.11%
2021	-24.98%	-62.00%
2020	+2.73%	-17.31%
2019	N/A	+100.52%
2018	N/A	-5.54%
2017	N/A	-0.41%
2016	N/A	-30.16%
2015	N/A	-65.12%
2014	N/A	+62.67%
2013	N/A	+42.80%

QSI vs KPTI Drawdown Comparison

The maximum drawdown for QSI was -97.18%, occurring on Nov 19, 2024. This drawdown has not yet recovered.

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The current QSI drawdown is -95.78%. The current KPTI drawdown is -98.66%.

Rank	QSI	KPTI
#1	-97.18% Feb 18, 2021 - Nov 19, 2024	-99.50% Jun 13, 2014 - Apr 1, 2025
#2	-13.13% Dec 4, 2020 - Feb 18, 2021	-43.74% Mar 6, 2014 - Jun 13, 2014
#3	-0.00% Nov 20, 2020 - Nov 30, 2020	-10.42% Dec 20, 2013 - Jan 15, 2014
#4	N/A	-9.08% Jan 31, 2014 - Feb 12, 2014
#5	N/A	-8.83% Mar 4, 2014 - Mar 6, 2014
#6	N/A	-5.88% Jan 22, 2014 - Jan 30, 2014
#7	N/A	-4.87% Feb 27, 2014 - Mar 4, 2014
#8	N/A	-4.36% Feb 13, 2014 - Feb 20, 2014
#9	N/A	-3.39% Dec 9, 2013 - Dec 13, 2013
#10	N/A	-1.60% Nov 29, 2013 - Dec 6, 2013
#11	N/A	-1.48% Nov 8, 2013 - Nov 29, 2013
#12	N/A	-0.44% Nov 6, 2013 - Nov 8, 2013