PTGX vs SLAB

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Silicon Laboratories Inc (SLAB, Company).

PTGX is from the Healthcare sector, while SLAB is from the Technology sector.

5-Year PerformancePTGX has outperformed SLAB, delivering a return of +21.6% compared to +9.3%

PTGX vs SLAB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	SLAB(COMPANY)
Market Cap	$7.25B	$7.24B
Max Drawdown	85.79%	89.29%
Sharpe Ratio	1.57	0.93
5Y Beta	0.25	1.61
Industry	Biotechnology	Semiconductors
P/E Ratio	-61.33	-143.54
Forward P/E	23.58	80.00
5Y EPS CAGR	1.43%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.63%	0.24%

Market Cap

Winner

PTGX

$7.25B

SLAB

$7.24B

Max Drawdown

Winner

PTGX

85.79%

SLAB

89.29%

Sharpe Ratio

Winner

PTGX

1.57

SLAB

0.93

5Y Beta

Winner

PTGX

0.25

SLAB

1.61

Industry

PTGX

Biotechnology

SLAB

Semiconductors

P/E Ratio

PTGX

-61.33

Winner

SLAB

-143.54

Forward P/E

Winner

PTGX

23.58

SLAB

80.00

5Y EPS CAGR

PTGX

1.43%

SLAB

N/A

Debt to Equity

PTGX

0.00%

SLAB

0.00%

Free Cash Flow Yield

PTGX

-1.63%

Winner

SLAB

0.24%

PTGX vs SLAB - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	SLAB
1 month	+12.03%	+1.45%
3 months	+16.24%	+6.81%
6 months	+31.55%	+63.40%
1 year	+109.31%	+55.83%
5 years(CAGR)	+21.59%	+9.29%
10 years(CAGR)	+25.87%	+16.21%
Max(CAGR)	+25.87%	+4.49%

Winner

PTGX

+12.03%

SLAB

+1.45%

Winner

PTGX

+16.24%

SLAB

+6.81%

PTGX

+31.55%

Winner

SLAB

+63.40%

Winner

PTGX

+109.31%

SLAB

+55.83%

5Y(CAGR)

Winner

PTGX

+21.59%

SLAB

+9.29%

10Y(CAGR)

Winner

PTGX

+25.87%

SLAB

+16.21%

Max(CAGR)

Winner

PTGX

+25.87%

SLAB

+4.49%

PTGX vs SLAB - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	PTGX	SLAB
2026	+29.46%	+66.57%
2025	+124.06%	+4.52%
2024	+64.82%	-2.86%
2023	+112.71%	-1.33%
2022	-69.11%	-33.66%
2021	+74.49%	+63.37%
2020	+190.91%	+7.54%
2019	+2.32%	+46.37%
2018	-68.18%	-13.30%
2017	-1.79%	+33.59%
2016	+87.95%	+37.04%
2015	N/A	+2.17%
2014	N/A	+13.54%
2013	N/A	-0.48%
2012	N/A	-4.89%
2011	N/A	-6.52%
2010	N/A	-4.14%
2009	N/A	+89.28%
2008	N/A	-32.79%
2007	N/A	+8.65%
2006	N/A	-8.89%
2005	N/A	+6.91%
2004	N/A	-20.29%
2003	N/A	+116.40%
2002	N/A	-44.36%
2001	N/A	+131.52%
2000	N/A	-79.27%

PTGX vs SLAB Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for SLAB was -89.29%, occurring on Dec 20, 2000. Recovery took 4455 trading sessions.

The current SLAB drawdown is -0.27%.

Rank	PTGX	SLAB
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-89.29% May 2, 2000 - Jan 17, 2018
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-58.99% Nov 16, 2021 - Apr 8, 2026
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-43.61% Jan 23, 2020 - Dec 4, 2020
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-33.01% Jun 6, 2018 - Apr 24, 2019
#5	-19.04% Mar 19, 2021 - May 18, 2021	-32.35% Mar 29, 2000 - May 1, 2000
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-24.51% Feb 19, 2021 - Oct 27, 2021
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-16.36% Apr 24, 2019 - Jul 24, 2019
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-14.25% Jan 26, 2018 - Mar 9, 2018
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-13.66% Mar 12, 2018 - May 8, 2018
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-11.89% Jul 30, 2019 - Dec 19, 2019
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-8.04% Jan 21, 2021 - Feb 8, 2021
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-4.46% Feb 12, 2021 - Feb 19, 2021
#13	-7.43% Mar 31, 2026 - Apr 15, 2026	-3.89% Nov 4, 2021 - Nov 15, 2021
#14	-7.20% Jun 14, 2021 - Jun 16, 2021	-2.81% Dec 4, 2020 - Dec 15, 2020
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-2.61% Jan 23, 2018 - Jan 26, 2018