PTGX vs ACMR

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and ACM Research Inc - Class A (ACMR, Company).

PTGX is from the Healthcare sector, while ACMR is from the Technology sector.

5-Year PerformanceACMR has outperformed PTGX, delivering a return of +26.5% compared to +21.6%

PTGX vs ACMR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	ACMR(COMPANY)
Market Cap	$7.25B	$7.23B
Max Drawdown	85.79%	87.23%
Sharpe Ratio	1.57	2.22
5Y Beta	0.25	2.14
Industry	Biotechnology	Semiconductor Equipment & Materials
P/E Ratio	-61.33	68.34
Forward P/E	23.58	59.88
PEG Ratio	N/A	80.83
5Y EPS CAGR	1.43%	42.23%
Debt to Equity	0.00%	14.81%
Free Cash Flow Yield	-1.63%	-1.48%

Market Cap

Winner

PTGX

$7.25B

ACMR

$7.23B

Max Drawdown

Winner

PTGX

85.79%

ACMR

87.23%

Sharpe Ratio

PTGX

1.57

Winner

ACMR

2.22

5Y Beta

Winner

PTGX

0.25

ACMR

2.14

Industry

PTGX

Biotechnology

ACMR

Semiconductor Equipment & Materials

P/E Ratio

Winner

PTGX

-61.33

ACMR

68.34

Forward P/E

Winner

PTGX

23.58

ACMR

59.88

PEG Ratio

PTGX

N/A

ACMR

80.83

5Y EPS CAGR

PTGX

1.43%

Winner

ACMR

42.23%

Debt to Equity

Winner

PTGX

0.00%

ACMR

14.81%

Free Cash Flow Yield

PTGX

-1.63%

Winner

ACMR

-1.48%

PTGX vs ACMR - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	ACMR
1 month	+12.03%	+73.71%
3 months	+16.24%	+135.77%
6 months	+31.55%	+190.58%
1 year	+109.31%	+336.17%
5 years(CAGR)	+21.59%	+26.50%
10 years(CAGR)	+25.87%	+59.00%
Max(CAGR)	+25.87%	+59.00%

PTGX

+12.03%

Winner

ACMR

+73.71%

PTGX

+16.24%

Winner

ACMR

+135.77%

PTGX

+31.55%

Winner

ACMR

+190.58%

PTGX

+109.31%

Winner

ACMR

+336.17%

5Y(CAGR)

PTGX

+21.59%

Winner

ACMR

+26.50%

10Y(CAGR)

PTGX

+25.87%

Winner

ACMR

+59.00%

Max(CAGR)

PTGX

+25.87%

Winner

ACMR

+59.00%

PTGX vs ACMR - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	PTGX	ACMR
2026	+29.46%	+144.81%
2025	+124.06%	+153.37%
2024	+64.82%	-19.12%
2023	+112.71%	+103.54%
2022	-69.11%	-74.15%
2021	+74.49%	-4.76%
2020	+190.91%	+329.21%
2019	+2.32%	+69.73%
2018	-68.18%	+93.60%
2017	-1.79%	-13.22%
2016	+87.95%	N/A

PTGX vs ACMR Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for ACMR was -87.23%, occurring on Oct 24, 2022. Recovery took 1228 trading sessions.

Rank	PTGX	ACMR
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-87.23% Feb 16, 2021 - Jan 6, 2026
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-64.46% Jan 22, 2020 - May 11, 2020
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-47.48% Aug 6, 2020 - Feb 11, 2021
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-46.34% Feb 11, 2026 - May 20, 2026
#5	-19.04% Mar 19, 2021 - May 18, 2021	-41.03% May 15, 2019 - Jan 7, 2020
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-38.02% Mar 14, 2018 - Mar 19, 2019
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-35.98% Nov 21, 2017 - Mar 5, 2018
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-19.52% May 19, 2020 - Jul 2, 2020
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-17.84% May 28, 2026 - Jun 12, 2026
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-15.59% Jul 14, 2020 - Jul 30, 2020
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-13.00% Apr 18, 2019 - May 7, 2019
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-11.92% Mar 21, 2019 - Apr 17, 2019
#13	-7.43% Mar 31, 2026 - Apr 15, 2026	-11.19% Feb 3, 2026 - Feb 6, 2026
#14	-7.20% Jun 14, 2021 - Jun 16, 2021	-10.29% May 12, 2020 - May 14, 2020
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-9.01% Jul 6, 2020 - Jul 8, 2020