PTGX vs SFB

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Stifel Financial Corp (SFB, Company).

5-Year PerformancePTGX has outperformed SFB, delivering a return of +22.6% compared to -1.3%

PTGX vs SFB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	SFB(COMPANY)
Market Cap	$6.79B	$6.77B
Max Drawdown	85.79%	39.52%
Sharpe Ratio	1.47	-0.28
5Y Beta	0.24	0.20
Industry	Biotechnology	Other
P/E Ratio	-57.48	N/A
Forward P/E	22.42	N/A
PEG Ratio	0.00	N/A
Dividend Yield	N/A	6.37%
5Y Dividends CAGR	N/A	4.56%
5Y EPS CAGR	1.43%	N/A
Debt to Equity	0.00%	N/A
Free Cash Flow Yield	-1.74%	N/A
P/S Ratio	95.50	N/A
P/B Ratio	10.39	N/A

Market Cap

Winner

PTGX

$6.79B

SFB

$6.77B

Max Drawdown

PTGX

85.79%

Winner

SFB

39.52%

Sharpe Ratio

Winner

PTGX

1.47

SFB

-0.28

5Y Beta

PTGX

0.24

Winner

SFB

0.20

Industry

PTGX

Biotechnology

SFB

Other

P/E Ratio

PTGX

-57.48

SFB

N/A

Forward P/E

PTGX

22.42

SFB

N/A

PEG Ratio

PTGX

0.00

SFB

N/A

Dividend Yield

PTGX

N/A

SFB

6.37%

5Y Dividends CAGR

PTGX

N/A

SFB

4.56%

5Y EPS CAGR

PTGX

1.43%

SFB

N/A

Debt to Equity

PTGX

0.00%

SFB

N/A

Free Cash Flow Yield

PTGX

-1.74%

SFB

N/A

P/S Ratio

PTGX

95.50

SFB

N/A

P/B Ratio

PTGX

10.39

SFB

N/A

PTGX vs SFB - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	SFB
1 month	+9.83%	-2.96%
3 months	+15.05%	+0.45%
6 months	+15.13%	-4.26%
1 year	+94.92%	+0.25%
5 years(CAGR)	+22.59%	-1.31%
10 years(CAGR)	+25.57%	+1.03%
Max(CAGR)	+25.57%	+1.03%

Winner

PTGX

+9.83%

SFB

-2.96%

Winner

PTGX

+15.05%

SFB

+0.45%

Winner

PTGX

+15.13%

SFB

-4.26%

Winner

PTGX

+94.92%

SFB

+0.25%

5Y(CAGR)

Winner

PTGX

+22.59%

SFB

-1.31%

10Y(CAGR)

Winner

PTGX

+25.57%

SFB

+1.03%

Max(CAGR)

Winner

PTGX

+25.57%

SFB

+1.03%

PTGX vs SFB - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	PTGX	SFB
2026	+25.92%	-3.25%
2025	+124.06%	+4.36%
2024	+64.82%	+5.81%
2023	+112.71%	+1.59%
2022	-69.11%	-17.44%
2021	+74.49%	+2.92%
2020	+190.91%	+6.35%
2019	+2.32%	+24.31%
2018	-68.18%	-16.37%
2017	-1.79%	+0.38%
2016	+87.95%	N/A

PTGX vs SFB Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for SFB was -39.13%, occurring on Mar 23, 2020. Recovery took 105 trading sessions.

The current PTGX drawdown is -0.01%. The current SFB drawdown is -10.72%.

Rank	PTGX	SFB
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-39.13% Feb 11, 2020 - Jul 13, 2020
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-28.05% Sep 16, 2021 - Oct 20, 2023
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-19.72% Nov 27, 2017 - Jun 18, 2019
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-9.22% Oct 7, 2020 - Sep 13, 2021
#5	-19.04% Mar 19, 2021 - May 18, 2021	-5.57% Sep 27, 2019 - Jan 27, 2020
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-3.59% Aug 12, 2020 - Sep 28, 2020
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-2.77% Jun 26, 2019 - Jul 19, 2019
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-2.50% Sep 6, 2019 - Sep 23, 2019
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-1.14% Jul 27, 2020 - Aug 12, 2020
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-1.07% Oct 19, 2017 - Nov 24, 2017
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-0.92% Jul 13, 2020 - Jul 15, 2020
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-0.91% Jul 19, 2019 - Jul 29, 2019
#13	-7.43% Mar 31, 2026 - Apr 15, 2026	-0.90% Jan 27, 2020 - Feb 7, 2020
#14	-7.20% Jun 14, 2021 - Jun 16, 2021	-0.85% Aug 6, 2019 - Aug 13, 2019
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-0.58% Oct 1, 2020 - Oct 6, 2020