PTGX vs COF-P-N

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Capital One Financial Corp (COF-P-N, Company).

5-Year PerformancePTGX has outperformed COF-P-N, delivering a return of +26.3% compared to -3.7%

PTGX vs COF-P-N - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	COF-P-N(COMPANY)
Market Cap	$9.83B	$9.79B
Max Drawdown	85.79%	46.41%
Sharpe Ratio	2.14	-0.84
5Y Beta	0.24	0.27
Industry	Biotechnology	N/A
P/E Ratio	122.81	3.01
Forward P/E	39.68	N/A
PEG Ratio	2.71	N/A
5Y EPS CAGR	N/A	-20.01%
Debt to Equity	0.00%	1.45%
Free Cash Flow Yield	1.33%	N/A
P/S Ratio	35.59	N/A
P/B Ratio	11.53	N/A

Market Cap

Winner

PTGX

$9.83B

COF-P-N

$9.79B

Max Drawdown

PTGX

85.79%

Winner

COF-P-N

46.41%

Sharpe Ratio

Winner

PTGX

2.14

COF-P-N

-0.84

5Y Beta

Winner

PTGX

0.24

COF-P-N

0.27

Industry

PTGX

Biotechnology

COF-P-N

N/A

P/E Ratio

PTGX

122.81

Winner

COF-P-N

3.01

Forward P/E

PTGX

39.68

COF-P-N

N/A

PEG Ratio

PTGX

2.71

COF-P-N

N/A

5Y EPS CAGR

PTGX

N/A

COF-P-N

-20.01%

Debt to Equity

Winner

PTGX

0.00%

COF-P-N

1.45%

Free Cash Flow Yield

PTGX

1.33%

COF-P-N

N/A

P/S Ratio

PTGX

35.59

COF-P-N

N/A

P/B Ratio

PTGX

11.53

COF-P-N

N/A

PTGX vs COF-P-N - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	COF-P-N
1 month	+15.39%	+0.38%
3 months	+57.51%	-0.58%
6 months	+86.47%	-5.53%
1 year	+175.45%	-5.47%
5 years(CAGR)	+26.29%	-3.66%
10 years(CAGR)	+29.37%	N/A
Max(CAGR)	+29.41%	-3.32%

Winner

PTGX

+15.39%

COF-P-N

+0.38%

Winner

PTGX

+57.51%

COF-P-N

-0.58%

Winner

PTGX

+86.47%

COF-P-N

-5.53%

Winner

PTGX

+175.45%

COF-P-N

-5.47%

5Y(CAGR)

Winner

PTGX

+26.29%

COF-P-N

-3.66%

10Y(CAGR)

PTGX

+29.37%

COF-P-N

N/A

Max(CAGR)

Winner

PTGX

+29.41%

COF-P-N

-3.32%

PTGX vs COF-P-N - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	PTGX	COF-P-N
2026	+77.72%	-2.46%
2025	+124.06%	+2.69%
2024	+64.82%	+10.09%
2023	+112.71%	+8.22%
2022	-69.11%	-34.57%
2021	+74.49%	+4.23%
2020	+190.91%	N/A
2019	+2.32%	N/A
2018	-68.18%	N/A
2017	-1.79%	N/A
2016	+87.95%	N/A

PTGX vs COF-P-N Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for COF-P-N was -40.35%, occurring on Oct 20, 2023. This drawdown has not yet recovered.

The current PTGX drawdown is -2.32%. The current COF-P-N drawdown is -19.17%.

Rank	PTGX	COF-P-N
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-40.35% Dec 29, 2021 - Oct 20, 2023
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-3.10% Sep 3, 2021 - Dec 16, 2021
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-1.07% Aug 3, 2021 - Aug 13, 2021
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-0.35% Aug 30, 2021 - Sep 2, 2021
#5	-19.04% Mar 19, 2021 - May 18, 2021	-0.32% Aug 20, 2021 - Aug 27, 2021
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-0.28% Aug 16, 2021 - Aug 20, 2021
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-0.24% Dec 16, 2021 - Dec 21, 2021
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-0.12% Dec 23, 2021 - Dec 28, 2021
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	N/A
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	N/A
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	N/A
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	N/A
#13	-7.78% Jul 7, 2026 - Jul 17, 2026	N/A
#14	-7.43% Mar 31, 2026 - Apr 15, 2026	N/A
#15	-7.20% Jun 14, 2021 - Jun 16, 2021	N/A

Correlation

Correlation between PTGX and COF-P-N is 0.34 which considered as a weak positive correlation - the stocks show a slight tendency to move together.

0.34

-101