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PGEN vs SEPN

Comparison between Precigen Inc (PGEN, Company) and Septerna Inc (SEPN, Company).

Both PGEN and SEPN are from the Healthcare sector.

PGEN vs SEPN - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
PGEN
$1.37B
SEPN
$1.37B
Max Drawdown
PGEN
99.01%
Winner
SEPN
81.47%
Sharpe Ratio
PGEN
1.46
Winner
SEPN
2.15
5Y Beta
PGEN
1.69
Winner
SEPN
1.33
Industry
PGEN
Biotechnology
SEPN
Biotechnology
P/E Ratio
PGEN
-6.58
Winner
SEPN
-37.80
Forward P/E
PGEN
196.08
Winner
SEPN
107.53
PEG Ratio
PGEN
-1.20
SEPN
N/A
5Y EPS CAGR
PGEN
-3.77%
SEPN
N/A
Debt to Equity
PGEN
462.16%
Winner
SEPN
0.00%
Free Cash Flow Yield
PGEN
-8.52%
Winner
SEPN
7.81%
P/S Ratio
PGEN
43.89
Winner
SEPN
19.01
P/B Ratio
PGEN
68.45
Winner
SEPN
3.62

PGEN vs SEPN - Historical Returns

Returns include dividend reinvestment.

1M
PGEN
+9.07%
Winner
SEPN
+44.73%
3M
PGEN
+35.67%
Winner
SEPN
+35.94%
6M
PGEN
+20.60%
Winner
SEPN
+41.31%
1Y
PGEN
+192.76%
Winner
SEPN
+245.34%
5Y(CAGR)
PGEN
-9.50%
SEPN
N/A
10Y(CAGR)
PGEN
-15.74%
SEPN
N/A
Max(CAGR)
PGEN
-11.88%
Winner
SEPN
+37.50%

PGEN vs SEPN - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

YearPGENSEPN
2026+3.97%+28.48%
2025+287.04%+30.59%
2024-20.57%+7.01%
2023-9.46%N/A
2022-61.81%N/A
2021-66.12%N/A
2020+72.59%N/A
2019-23.36%N/A
2018-51.45%N/A
2017-52.67%N/A
2016-16.70%N/A
2015+24.14%N/A
2014+15.96%N/A
2013-3.76%N/A

PGEN vs SEPN Drawdown Comparison

The maximum drawdown for PGEN was -99.00%, occurring on Dec 16, 2024. This drawdown has not yet recovered.

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The current PGEN drawdown is -93.40%.

RankPGENSEPN
#1-99.00%
Aug 5, 2015 - Dec 16, 2024
-81.47%
Dec 23, 2024 - Nov 24, 2025
#2-58.45%
Jan 17, 2014 - Jan 14, 2015
-25.18%
Feb 24, 2026 - May 28, 2026
#3-40.57%
Aug 12, 2013 - Jan 10, 2014
-21.10%
Dec 19, 2025 - Feb 17, 2026
#4-26.70%
Jan 14, 2015 - Feb 12, 2015
-16.77%
Dec 4, 2024 - Dec 23, 2024
#5-22.81%
Mar 6, 2015 - Jun 17, 2015
-16.19%
Nov 7, 2024 - Dec 4, 2024
#6-11.24%
Jun 22, 2015 - Jul 15, 2015
-13.97%
Nov 26, 2025 - Dec 19, 2025
#7-7.34%
Jul 22, 2015 - Jul 28, 2015
-10.63%
Feb 17, 2026 - Feb 24, 2026
#8-6.29%
Feb 26, 2015 - Mar 3, 2015
-6.45%
Oct 25, 2024 - Oct 31, 2024
#9-4.31%
Feb 20, 2015 - Feb 25, 2015
-4.76%
Oct 31, 2024 - Nov 4, 2024
#10-3.78%
Jan 10, 2014 - Jan 14, 2014
-3.57%
May 28, 2026 - Jun 4, 2026
#11-2.04%
Jul 20, 2015 - Jul 22, 2015
-3.45%
Nov 4, 2024 - Nov 6, 2024
#12-1.38%
Feb 17, 2015 - Feb 19, 2015
-3.06%
Jun 4, 2026 - Jun 11, 2026
#13-0.60%
Jun 17, 2015 - Jun 19, 2015
-1.89%
Nov 24, 2025 - Nov 26, 2025
#14-0.08%
Mar 3, 2015 - Mar 5, 2015
N/A
#15-0.08%
Jul 31, 2015 - Aug 4, 2015
N/A

Correlation

Correlation between PGEN and SEPN is 0.56 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.56
-101

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