OR vs SYRE

Comparison between Osisko Gold Royalties Ltd (OR, Company) and Spyre Therapeutics Inc (SYRE, Company).

OR is from the Basic Materials sector, while SYRE is from the Healthcare sector.

5-Year PerformanceOR has outperformed SYRE, delivering a return of +19.7% compared to -13.3%

OR vs SYRE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	OR(COMPANY)	SYRE(COMPANY)
Market Cap	$5.94B	$5.92B
Max Drawdown	63.70%	99.11%
Sharpe Ratio	0.70	2.43
5Y Beta	0.58	1.75
Industry	Gold	Biotechnology
P/E Ratio	37.08	-30.42
Forward P/E	23.26	N/A
PEG Ratio	0.05	N/A
Dividend Yield	0.67%	N/A
5Y Dividends CAGR	11.61%	N/A
5Y EPS CAGR	35.27%	-2.15%
Debt to Equity	0.31%	0.00%
Free Cash Flow Yield	1.57%	-3.14%
P/S Ratio	18.82	650.22
P/B Ratio	4.21	12.66

Market Cap

Winner

$5.94B

SYRE

$5.92B

Max Drawdown

Winner

63.70%

SYRE

99.11%

Sharpe Ratio

0.70

Winner

SYRE

2.43

5Y Beta

Winner

0.58

SYRE

1.75

Industry

Gold

SYRE

Biotechnology

P/E Ratio

37.08

Winner

SYRE

-30.42

Forward P/E

23.26

SYRE

N/A

PEG Ratio

0.05

SYRE

N/A

Dividend Yield

0.67%

SYRE

N/A

5Y Dividends CAGR

11.61%

SYRE

N/A

5Y EPS CAGR

Winner

35.27%

SYRE

-2.15%

Debt to Equity

0.31%

Winner

SYRE

0.00%

Free Cash Flow Yield

Winner

1.57%

SYRE

-3.14%

P/S Ratio

Winner

18.82

SYRE

650.22

P/B Ratio

Winner

4.21

SYRE

12.66

OR vs SYRE - Historical Returns

Returns include dividend reinvestment.

Period	OR	SYRE
1 month	-14.59%	+7.66%
3 months	-19.43%	+99.93%
6 months	-5.88%	+140.30%
1 year	+28.93%	+356.18%
5 years(CAGR)	+19.72%	-13.30%
10 years(CAGR)	+11.59%	-6.27%
Max(CAGR)	+13.79%	-10.30%

-14.59%

Winner

SYRE

+7.66%

-19.43%

Winner

SYRE

+99.93%

-5.88%

Winner

SYRE

+140.30%

+28.93%

Winner

SYRE

+356.18%

5Y(CAGR)

Winner

+19.72%

SYRE

-13.30%

10Y(CAGR)

Winner

+11.59%

SYRE

-6.27%

Max(CAGR)

Winner

+13.79%

SYRE

-10.30%

OR vs SYRE - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	OR	SYRE
2026	-3.78%	+164.19%
2025	+91.23%	+37.36%
2024	+29.95%	+8.79%
2023	+18.19%	+104.27%
2022	+2.76%	-90.57%
2021	-5.73%	-44.51%
2020	+32.40%	+1.55%
2019	+10.84%	-4.98%
2018	-22.58%	+39.22%
2017	+17.93%	+18.38%
2016	-2.30%	-55.48%

OR vs SYRE Drawdown Comparison

The maximum drawdown for OR was -61.89%, occurring on Mar 13, 2020. Recovery took 924 trading sessions.

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The current OR drawdown is -29.02%. The current SYRE drawdown is -73.05%.

Rank	OR	SYRE
#1	-61.89% Sep 7, 2017 - May 11, 2021	-99.11% Apr 8, 2016 - Jun 21, 2023
#2	-38.15% Aug 1, 2016 - Sep 7, 2017	N/A
#3	-37.19% Jun 15, 2021 - Mar 17, 2023	N/A
#4	-34.29% May 3, 2023 - Jul 15, 2024	N/A
#5	-33.97% Mar 2, 2026 - Jun 10, 2026	N/A
#6	-24.49% Oct 7, 2025 - Jan 13, 2026	N/A
#7	-17.41% Jan 28, 2026 - Feb 26, 2026	N/A
#8	-14.86% Oct 22, 2024 - Mar 25, 2025	N/A
#9	-14.77% Apr 29, 2016 - Jun 9, 2016	N/A
#10	-14.72% Feb 8, 2016 - Apr 11, 2016	N/A
#11	-12.31% Jul 17, 2024 - Sep 20, 2024	N/A
#12	-12.18% Jan 7, 2016 - Feb 1, 2016	N/A
#13	-11.80% Jul 6, 2016 - Aug 1, 2016	N/A
#14	-8.90% Mar 31, 2025 - Apr 10, 2025	N/A
#15	-7.72% May 9, 2025 - May 20, 2025	N/A

Correlation

Correlation between OR and SYRE is -0.52 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.52

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