NBIX vs SPY
Comparison between Neurocrine Biosciences Inc (NBIX, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed NBIX, delivering a return of +13.3% compared to +10.8%
NBIX vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
NBIX
$15B
Winner
SPY
$652B
Expense Ratio
NBIX
N/A
SPY
0.09%
Max Drawdown
NBIX
97.21%
Winner
SPY
56.47%
Sharpe Ratio
NBIX
0.77
Winner
SPY
2.07
5Y Beta
Winner
NBIX
0.82
SPY
1.00
Industry
NBIX
Drug Manufacturers - Specialty & Generic
SPY
N/A
P/E Ratio
Winner
NBIX
21.98
SPY
28.24
Forward P/E
NBIX
23.81
Winner
SPY
21.85
PEG Ratio
NBIX
0.18
SPY
N/A
5Y Dividends CAGR
NBIX
N/A
SPY
5.43%
5Y EPS CAGR
NBIX
9.25%
Winner
SPY
25.79%
Debt to Equity
Winner
NBIX
0.00%
SPY
22.35%
Free Cash Flow Yield
NBIX
5.59%
SPY
N/A
P/S Ratio
NBIX
5.17
Winner
SPY
3.55
P/B Ratio
Winner
NBIX
4.14
SPY
5.29
NBIX vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
Winner
NBIX
+14.34%
SPY
+9.11%
3M
Winner
NBIX
+9.09%
SPY
+6.59%
6M
NBIX
-0.08%
Winner
SPY
+10.56%
1Y
NBIX
+29.55%
Winner
SPY
+32.04%
5Y(CAGR)
NBIX
+10.83%
Winner
SPY
+13.35%
10Y(CAGR)
NBIX
+13.00%
Winner
SPY
+15.49%
Max(CAGR)
Winner
NBIX
+12.32%
SPY
+8.50%
NBIX vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | NBIX | SPY |
|---|---|---|
| 2026 | +8.29% | +8.27% |
| 2025 | +2.88% | +18.00% |
| 2024 | +3.62% | +25.59% |
| 2023 | +9.73% | +26.72% |
| 2022 | +35.01% | -18.64% |
| 2021 | -11.16% | +30.52% |
| 2020 | -11.50% | +17.28% |
| 2019 | +53.36% | +31.09% |
| 2018 | -9.95% | -5.24% |
| 2017 | +100.70% | +20.78% |
| 2016 | -26.07% | +13.59% |
| 2015 | +147.68% | +1.31% |
| 2014 | +133.93% | +14.56% |
| 2013 | +14.74% | +29.00% |
| 2012 | -12.51% | +14.17% |
| 2011 | +10.82% | +0.85% |
| 2010 | +184.01% | +13.14% |
| 2009 | -16.82% | +22.67% |
| 2008 | -29.20% | -36.25% |
| 2007 | -55.79% | +5.32% |
| 2006 | -83.61% | +13.85% |
| 2005 | +27.97% | +5.32% |
| 2004 | -11.17% | +10.75% |
| 2003 | +20.11% | +24.18% |
| 2002 | -9.71% | -22.42% |
| 2001 | +59.40% | -10.13% |
| 2000 | +33.86% | -8.84% |
| 1999 | +253.57% | +8.61% |
NBIX vs SPY Drawdown Comparison
The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current NBIX drawdown is -2.17%.
| Rank | NBIX | SPY |
|---|---|---|
| #1 | -97.21% Mar 15, 2006 - Nov 2, 2017 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -66.15% Mar 3, 2000 - Nov 20, 2001 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -54.12% Dec 24, 2001 - Jun 5, 2003 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -50.71% Apr 27, 2004 - Feb 27, 2006 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -46.39% Jul 15, 2020 - Jan 17, 2024 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -45.71% Sep 4, 2018 - Jun 19, 2020 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -42.89% Jan 30, 2025 - Nov 5, 2025 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -28.57% Jan 21, 2000 - Feb 16, 2000 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -27.12% Aug 1, 2024 - Jan 30, 2025 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -22.86% Dec 2, 1999 - Dec 13, 1999 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -21.32% Jun 16, 2003 - Jan 23, 2004 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -20.90% Dec 10, 2025 - Feb 12, 2026 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -19.01% Dec 29, 1999 - Jan 10, 2000 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -18.53% Mar 9, 2018 - May 15, 2018 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | -13.74% Jan 26, 2004 - Mar 4, 2004 | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between NBIX and SPY is 0.87 which considered as a strong positive correlation - the stocks tend to move together.
0.87
-101
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