NBIX vs MEDP

Comparison between Neurocrine Biosciences Inc (NBIX, Company) and Medpace Holdings Inc (MEDP, Company).

Both NBIX and MEDP are from the Healthcare sector.

5-Year PerformanceMEDP has outperformed NBIX, delivering a return of +26.9% compared to +12.3%

NBIX vs MEDP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NBIX(COMPANY)	MEDP(COMPANY)
Market Cap	$16B	$16B
Max Drawdown	97.21%	42.87%
Sharpe Ratio	0.71	0.81
5Y Beta	0.81	0.98
Industry	Drug Manufacturers - Specialty & Generic	Diagnostics & Research
P/E Ratio	22.99	33.79
Forward P/E	24.51	33.56
PEG Ratio	0.23	1.38
5Y EPS CAGR	12.54%	28.77%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	5.28%	4.31%
P/S Ratio	4.87	5.90
P/B Ratio	4.57	37.09

Market Cap

Winner

NBIX

$16B

MEDP

$16B

Max Drawdown

NBIX

97.21%

Winner

MEDP

42.87%

Sharpe Ratio

NBIX

0.71

Winner

MEDP

0.81

5Y Beta

Winner

NBIX

0.81

MEDP

0.98

Industry

NBIX

Drug Manufacturers - Specialty & Generic

MEDP

Diagnostics & Research

P/E Ratio

Winner

NBIX

22.99

MEDP

33.79

Forward P/E

Winner

NBIX

24.51

MEDP

33.56

PEG Ratio

Winner

NBIX

0.23

MEDP

1.38

5Y EPS CAGR

NBIX

12.54%

Winner

MEDP

28.77%

Debt to Equity

NBIX

0.00%

MEDP

0.00%

Free Cash Flow Yield

Winner

NBIX

5.28%

MEDP

4.31%

P/S Ratio

Winner

NBIX

4.87

MEDP

5.90

P/B Ratio

Winner

NBIX

4.57

MEDP

37.09

NBIX vs MEDP - Historical Returns

Returns include dividend reinvestment.

Period	NBIX	MEDP
1 month	-8.20%	+3.53%
3 months	+8.71%	+37.07%
6 months	+13.19%	+7.93%
1 year	+24.44%	+35.93%
5 years(CAGR)	+12.28%	+26.89%
10 years(CAGR)	+12.33%	+35.68%
Max(CAGR)	+12.40%	+35.68%

NBIX

-8.20%

Winner

MEDP

+3.53%

NBIX

+8.71%

Winner

MEDP

+37.07%

Winner

NBIX

+13.19%

MEDP

+7.93%

NBIX

+24.44%

Winner

MEDP

+35.93%

5Y(CAGR)

NBIX

+12.28%

Winner

MEDP

+26.89%

10Y(CAGR)

NBIX

+12.33%

Winner

MEDP

+35.68%

Max(CAGR)

NBIX

+12.40%

Winner

MEDP

+35.68%

NBIX vs MEDP - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	NBIX	MEDP
2026	+13.67%	+2.45%
2025	+2.88%	+67.78%
2024	+3.62%	+8.72%
2023	+9.73%	+47.17%
2022	+35.01%	-0.89%
2021	-11.16%	+61.91%
2020	-11.50%	+67.77%
2019	+53.36%	+60.42%
2018	-9.95%	+42.51%
2017	+100.70%	+0.97%
2016	-26.07%	+29.79%
2015	+147.68%	N/A
2014	+133.93%	N/A
2013	+14.74%	N/A
2012	-12.51%	N/A
2011	+10.82%	N/A
2010	+184.01%	N/A
2009	-16.82%	N/A
2008	-29.20%	N/A
2007	-55.79%	N/A
2006	-83.61%	N/A
2005	+27.97%	N/A
2004	-11.17%	N/A
2003	+20.11%	N/A
2002	-9.71%	N/A
2001	+59.40%	N/A
2000	+31.89%	N/A
1999	+253.57%	N/A

NBIX vs MEDP Drawdown Comparison

The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.

The maximum drawdown for MEDP was -42.87%, occurring on Apr 27, 2022. Recovery took 264 trading sessions.

The current NBIX drawdown is -13.84%. The current MEDP drawdown is -5.73%.

Rank	NBIX	MEDP
#1	-97.21% Mar 15, 2006 - Nov 2, 2017	-42.87% Dec 27, 2021 - Jan 13, 2023
#2	-66.15% Mar 3, 2000 - Nov 20, 2001	-41.43% Dec 6, 2016 - Dec 19, 2017
#3	-54.12% Dec 24, 2001 - Jun 5, 2003	-39.47% Feb 25, 2020 - Jul 15, 2020
#4	-50.71% Apr 27, 2004 - Feb 27, 2006	-39.38% Jul 16, 2024 - Jul 22, 2025
#5	-46.39% Jul 15, 2020 - Jan 17, 2024	-36.61% Jan 21, 2026 - Apr 23, 2026
#6	-45.71% Sep 4, 2018 - Jun 19, 2020	-27.23% Jan 23, 2023 - Jun 30, 2023
#7	-42.89% Jan 30, 2025 - Nov 5, 2025	-27.15% Feb 25, 2019 - Jul 30, 2019
#8	-28.57% Jan 21, 2000 - Feb 16, 2000	-26.31% Sep 18, 2018 - Dec 3, 2018
#9	-27.12% Aug 1, 2024 - Jan 30, 2025	-26.07% Dec 3, 2018 - Jan 31, 2019
#10	-22.86% Dec 2, 1999 - Dec 13, 1999	-19.22% Sep 13, 2023 - Nov 14, 2023
#11	-21.32% Jun 16, 2003 - Jan 23, 2004	-18.41% Sep 17, 2019 - Jan 14, 2020
#12	-20.90% Dec 10, 2025 - May 12, 2026	-18.36% Apr 26, 2021 - Sep 3, 2021
#13	-19.01% Dec 29, 1999 - Jan 10, 2000	-18.12% Sep 2, 2020 - Dec 1, 2020
#14	-18.53% Mar 9, 2018 - May 15, 2018	-17.99% Feb 26, 2018 - May 7, 2018
#15	-13.84% Jul 30, 2026 - Aug 6, 2026	-12.03% Nov 24, 2025 - Jan 21, 2026