NBIX vs CNFR

Comparison between Neurocrine Biosciences Inc (NBIX, Company) and Conifer Holdings Inc (CNFR, Company).

NBIX is from the Healthcare sector, while CNFR is from the Financial Services sector.

5-Year PerformanceNBIX has outperformed CNFR, delivering a return of +12.3% compared to -12.4%

NBIX vs CNFR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NBIX(COMPANY)	CNFR(COMPANY)
Market Cap	$16B	$18B
Max Drawdown	97.21%	95.67%
Sharpe Ratio	0.71	0.77
5Y Beta	0.81	0.01
Industry	Drug Manufacturers - Specialty & Generic	Insurance - Property & Casualty
P/E Ratio	22.99	593.48
Forward P/E	24.51	90.79
PEG Ratio	0.23	N/A
5Y EPS CAGR	12.54%	N/A
Debt to Equity	0.00%	42.75%
Free Cash Flow Yield	5.28%	-0.27%
P/S Ratio	4.87	292.82
P/B Ratio	4.57	641.30

Market Cap

NBIX

$16B

Winner

CNFR

$18B

Max Drawdown

NBIX

97.21%

Winner

CNFR

95.67%

Sharpe Ratio

NBIX

0.71

Winner

CNFR

0.77

5Y Beta

NBIX

0.81

Winner

CNFR

0.01

Industry

NBIX

Drug Manufacturers - Specialty & Generic

CNFR

Insurance - Property & Casualty

P/E Ratio

Winner

NBIX

22.99

CNFR

593.48

Forward P/E

Winner

NBIX

24.51

CNFR

90.79

PEG Ratio

NBIX

0.23

CNFR

N/A

5Y EPS CAGR

NBIX

12.54%

CNFR

N/A

Debt to Equity

Winner

NBIX

0.00%

CNFR

42.75%

Free Cash Flow Yield

Winner

NBIX

5.28%

CNFR

-0.27%

P/S Ratio

Winner

NBIX

4.87

CNFR

292.82

P/B Ratio

Winner

NBIX

4.57

CNFR

641.30

NBIX vs CNFR - Historical Returns

Returns include dividend reinvestment.

Period	NBIX	CNFR
1 month	-8.20%	+88.63%
3 months	+8.71%	+104.14%
6 months	+13.19%	+116.69%
1 year	+24.44%	+35.78%
5 years(CAGR)	+12.28%	-12.41%
10 years(CAGR)	+12.33%	-17.25%
Max(CAGR)	+12.40%	-17.66%

NBIX

-8.20%

Winner

CNFR

+88.63%

NBIX

+8.71%

Winner

CNFR

+104.14%

NBIX

+13.19%

Winner

CNFR

+116.69%

NBIX

+24.44%

Winner

CNFR

+35.78%

5Y(CAGR)

Winner

NBIX

+12.28%

CNFR

-12.41%

10Y(CAGR)

Winner

NBIX

+12.33%

CNFR

-17.25%

Max(CAGR)

Winner

NBIX

+12.40%

CNFR

-17.66%

NBIX vs CNFR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	NBIX	CNFR
2026	+13.67%	N/A
2025	+2.88%	+32.14%
2024	+3.62%	-15.22%
2023	+9.73%	-25.23%
2022	+35.01%	-33.76%
2021	-11.16%	-25.16%
2020	-11.50%	-18.56%
2019	+53.36%	+8.11%
2018	-9.95%	-39.13%
2017	+100.70%	-25.16%
2016	-26.07%	-11.61%
2015	+147.68%	-12.55%
2014	+133.93%	N/A
2013	+14.74%	N/A
2012	-12.51%	N/A
2011	+10.82%	N/A
2010	+184.01%	N/A
2009	-16.82%	N/A
2008	-29.20%	N/A
2007	-55.79%	N/A
2006	-83.61%	N/A
2005	+27.97%	N/A
2004	-11.17%	N/A
2003	+20.11%	N/A
2002	-9.71%	N/A
2001	+59.40%	N/A
2000	+31.89%	N/A
1999	+253.57%	N/A

NBIX vs CNFR Drawdown Comparison

The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.

The maximum drawdown for CNFR was -95.67%, occurring on Apr 3, 2025. This drawdown has not yet recovered.

The current NBIX drawdown is -13.84%. The current CNFR drawdown is -86.04%.

Rank	NBIX	CNFR
#1	-97.21% Mar 15, 2006 - Nov 2, 2017	-95.67% Aug 13, 2015 - Apr 3, 2025
#2	-66.15% Mar 3, 2000 - Nov 20, 2001	N/A
#3	-54.12% Dec 24, 2001 - Jun 5, 2003	N/A
#4	-50.71% Apr 27, 2004 - Feb 27, 2006	N/A
#5	-46.39% Jul 15, 2020 - Jan 17, 2024	N/A
#6	-45.71% Sep 4, 2018 - Jun 19, 2020	N/A
#7	-42.89% Jan 30, 2025 - Nov 5, 2025	N/A
#8	-28.57% Jan 21, 2000 - Feb 16, 2000	N/A
#9	-27.12% Aug 1, 2024 - Jan 30, 2025	N/A
#10	-22.86% Dec 2, 1999 - Dec 13, 1999	N/A
#11	-21.32% Jun 16, 2003 - Jan 23, 2004	N/A
#12	-20.90% Dec 10, 2025 - May 12, 2026	N/A
#13	-19.01% Dec 29, 1999 - Jan 10, 2000	N/A
#14	-18.53% Mar 9, 2018 - May 15, 2018	N/A
#15	-13.84% Jul 30, 2026 - Aug 6, 2026	N/A