MMSI vs DNLI

Comparison between Merit Medical Systems Inc (MMSI, Company) and Denali Therapeutics Inc (DNLI, Company).

Both MMSI and DNLI are from the Healthcare sector.

5-Year PerformanceMMSI has outperformed DNLI, delivering a return of +3.0% compared to -18.7%

MMSI vs DNLI - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	MMSI(COMPANY)	DNLI(COMPANY)
Market Cap	$4.24B	$4.23B
Max Drawdown	68.67%	87.74%
Sharpe Ratio	-0.82	1.17
5Y Beta	0.73	1.50
Industry	Medical Instruments & Supplies	Biotechnology
P/E Ratio	30.30	-7.97
Forward P/E	18.05	N/A
PEG Ratio	2.46	-1.24
5Y EPS CAGR	99.24%	N/A
Debt to Equity	45.19%	0.00%
Free Cash Flow Yield	5.21%	-9.97%
P/S Ratio	2.75	3643.65
P/B Ratio	2.62	4.43

Market Cap

Winner

MMSI

$4.24B

DNLI

$4.23B

Max Drawdown

Winner

MMSI

68.67%

DNLI

87.74%

Sharpe Ratio

MMSI

-0.82

Winner

DNLI

1.17

5Y Beta

Winner

MMSI

0.73

DNLI

1.50

Industry

MMSI

Medical Instruments & Supplies

DNLI

Biotechnology

P/E Ratio

MMSI

30.30

Winner

DNLI

-7.97

Forward P/E

MMSI

18.05

DNLI

N/A

PEG Ratio

MMSI

2.46

Winner

DNLI

-1.24

5Y EPS CAGR

MMSI

99.24%

DNLI

N/A

Debt to Equity

MMSI

45.19%

Winner

DNLI

0.00%

Free Cash Flow Yield

Winner

MMSI

5.21%

DNLI

-9.97%

P/S Ratio

Winner

MMSI

2.75

DNLI

3643.65

P/B Ratio

Winner

MMSI

2.62

DNLI

4.43

MMSI vs DNLI - Historical Returns

Returns include dividend reinvestment.

Period	MMSI	DNLI
1 month	+9.63%	+24.60%
3 months	+7.59%	+33.54%
6 months	-14.98%	+50.35%
1 year	-22.83%	+67.30%
5 years(CAGR)	+2.98%	-18.68%
10 years(CAGR)	+13.52%	+2.12%
Max(CAGR)	+15.04%	+2.12%

MMSI

+9.63%

Winner

DNLI

+24.60%

MMSI

+7.59%

Winner

DNLI

+33.54%

MMSI

-14.98%

Winner

DNLI

+50.35%

MMSI

-22.83%

Winner

DNLI

+67.30%

5Y(CAGR)

Winner

MMSI

+2.98%

DNLI

-18.68%

10Y(CAGR)

Winner

MMSI

+13.52%

DNLI

+2.12%

Max(CAGR)

Winner

MMSI

+15.04%

DNLI

+2.12%

MMSI vs DNLI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MMSI	DNLI
2026	-15.05%	+57.84%
2025	-8.25%	-20.78%
2024	+26.63%	-4.72%
2023	+9.14%	-22.33%
2022	+10.65%	-41.17%
2021	+13.77%	-37.06%
2020	+76.45%	+411.04%
2019	-41.32%	-9.88%
2018	+28.15%	+28.08%
2017	+64.89%	-27.09%
2016	+46.73%	N/A
2015	+10.13%	N/A
2014	+14.09%	N/A
2013	+12.27%	N/A
2012	+2.13%	N/A
2011	+4.66%	N/A
2010	-19.85%	N/A
2009	+8.15%	N/A
2008	+26.80%	N/A
2007	-12.58%	N/A
2006	+27.74%	N/A
2005	-18.25%	N/A
2004	-31.45%	N/A
2003	+90.35%	N/A
2002	+35.03%	N/A
2001	+344.76%	N/A
2000	-19.64%	N/A
1999	+19.58%	N/A

MMSI vs DNLI Drawdown Comparison

The maximum drawdown for MMSI was -68.67%, occurring on Oct 31, 2019. Recovery took 710 trading sessions.

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current MMSI drawdown is -33.41%. The current DNLI drawdown is -72.55%.

Rank	MMSI	DNLI
#1	-68.67% Oct 3, 2018 - Jul 30, 2021	-87.74% Dec 22, 2020 - Apr 8, 2025
#2	-63.64% Mar 24, 2000 - Jul 27, 2001	-49.76% Feb 16, 2018 - Apr 2, 2019
#3	-61.24% Jan 5, 2004 - Apr 24, 2015	-49.54% Apr 10, 2019 - Jun 2, 2020
#4	-45.32% Jan 30, 2025 - May 11, 2026	-29.88% Dec 8, 2017 - Jan 22, 2018
#5	-38.69% Jul 28, 2015 - Dec 8, 2016	-19.74% Jun 3, 2020 - Aug 6, 2020
#6	-34.70% Oct 11, 2001 - Jan 3, 2002	-19.58% Jan 29, 2018 - Feb 16, 2018
#7	-30.94% Jan 3, 2002 - Apr 8, 2002	-13.33% Nov 12, 2020 - Dec 4, 2020
#8	-29.43% Sep 2, 2021 - Dec 12, 2022	-11.16% Aug 10, 2020 - Aug 25, 2020
#9	-28.96% Nov 1, 2002 - Jul 24, 2003	-10.43% Sep 17, 2020 - Oct 7, 2020
#10	-26.18% Jun 7, 2023 - Jun 28, 2024	-10.33% Oct 13, 2020 - Oct 27, 2020
#11	-22.85% Jun 27, 2002 - Oct 3, 2002	-9.64% Aug 25, 2020 - Sep 14, 2020
#12	-20.06% Jul 30, 2001 - Aug 13, 2001	-7.28% Oct 28, 2020 - Nov 4, 2020
#13	-20.05% Apr 9, 2002 - Jun 18, 2002	-3.20% Jan 23, 2018 - Jan 26, 2018
#14	-18.94% Oct 5, 2017 - Jan 16, 2018	-2.37% Apr 3, 2019 - Apr 5, 2019
#15	-16.57% Oct 17, 2002 - Oct 30, 2002	-1.33% Dec 16, 2020 - Dec 18, 2020