DNLI vs BRC

Comparison between Denali Therapeutics Inc (DNLI, Company) and Brady Corp - Class A (BRC, Company).

DNLI is from the Healthcare sector, while BRC is from the Industrials sector.

5-Year PerformanceBRC has outperformed DNLI, delivering a return of +12.3% compared to -18.7%

DNLI vs BRC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	BRC(COMPANY)
Market Cap	$4.23B	$4.23B
Max Drawdown	87.74%	66.63%
Sharpe Ratio	1.17	0.89
5Y Beta	1.50	0.61
Industry	Biotechnology	Security & Protection Services
P/E Ratio	-7.97	19.97
Forward P/E	N/A	15.36
PEG Ratio	-1.24	1.10
Dividend Yield	N/A	1.09%
5Y Dividends CAGR	N/A	6.72%
5Y EPS CAGR	N/A	12.27%
Debt to Equity	0.00%	2.00%
Free Cash Flow Yield	-9.97%	4.29%
P/S Ratio	3643.65	2.60
P/B Ratio	4.43	3.22

Market Cap

Winner

DNLI

$4.23B

BRC

$4.23B

Max Drawdown

DNLI

87.74%

Winner

BRC

66.63%

Sharpe Ratio

Winner

DNLI

1.17

BRC

0.89

5Y Beta

DNLI

1.50

Winner

BRC

0.61

Industry

DNLI

Biotechnology

BRC

Security & Protection Services

P/E Ratio

Winner

DNLI

-7.97

BRC

19.97

Forward P/E

DNLI

N/A

BRC

15.36

PEG Ratio

Winner

DNLI

-1.24

BRC

1.10

Dividend Yield

DNLI

N/A

BRC

1.09%

5Y Dividends CAGR

DNLI

N/A

BRC

6.72%

5Y EPS CAGR

DNLI

N/A

BRC

12.27%

Debt to Equity

Winner

DNLI

0.00%

BRC

2.00%

Free Cash Flow Yield

DNLI

-9.97%

Winner

BRC

4.29%

P/S Ratio

DNLI

3643.65

Winner

BRC

2.60

P/B Ratio

DNLI

4.43

Winner

BRC

3.22

DNLI vs BRC - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	BRC
1 month	+24.60%	+15.80%
3 months	+33.54%	+7.64%
6 months	+50.35%	+10.00%
1 year	+67.30%	+30.95%
5 years(CAGR)	-18.68%	+12.31%
10 years(CAGR)	+2.12%	+13.15%
Max(CAGR)	+2.12%	+9.30%

Winner

DNLI

+24.60%

BRC

+15.80%

Winner

DNLI

+33.54%

BRC

+7.64%

Winner

DNLI

+50.35%

BRC

+10.00%

Winner

DNLI

+67.30%

BRC

+30.95%

5Y(CAGR)

DNLI

-18.68%

Winner

BRC

+12.31%

10Y(CAGR)

DNLI

+2.12%

Winner

BRC

+13.15%

Max(CAGR)

DNLI

+2.12%

Winner

BRC

+9.30%

DNLI vs BRC - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DNLI	BRC
2026	+57.84%	+15.33%
2025	-20.78%	+8.08%
2024	-4.72%	+22.34%
2023	-22.33%	+28.55%
2022	-41.17%	-11.59%
2021	-37.06%	+6.24%
2020	+411.04%	-6.96%
2019	-9.88%	+34.21%
2018	+28.08%	+12.11%
2017	-27.09%	+4.50%
2016	N/A	+75.30%
2015	N/A	-11.56%
2014	N/A	-9.64%
2013	N/A	-8.22%
2012	N/A	+5.52%
2011	N/A	-4.30%
2010	N/A	+7.12%
2009	N/A	+26.23%
2008	N/A	-30.04%
2007	N/A	-4.35%
2006	N/A	+2.07%
2005	N/A	+21.65%
2004	N/A	+57.12%
2003	N/A	+21.26%
2002	N/A	-6.91%
2001	N/A	+12.96%
2000	N/A	+4.74%
1999	N/A	+15.29%

DNLI vs BRC Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for BRC was -65.61%, occurring on Mar 9, 2009. Recovery took 2290 trading sessions.

The current DNLI drawdown is -72.55%. The current BRC drawdown is -6.12%.

Rank	DNLI	BRC
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-65.61% Aug 9, 2007 - Sep 13, 2016
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-36.21% Nov 26, 2019 - Mar 12, 2021
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-35.33% Apr 16, 2002 - Dec 1, 2003
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-30.06% Jun 8, 2021 - Dec 14, 2023
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-28.00% Dec 29, 1999 - Dec 28, 2000
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-26.33% Feb 7, 2001 - Apr 12, 2002
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-26.12% Feb 13, 2026 - May 15, 2026
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-25.08% May 17, 2006 - Aug 8, 2007
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-22.83% Mar 4, 2005 - Nov 17, 2005
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-19.23% May 5, 2017 - Nov 16, 2017
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-17.50% Dec 30, 2003 - May 25, 2004
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-16.06% Dec 23, 2004 - Feb 16, 2005
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-15.98% Nov 11, 2024 - Aug 22, 2025
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-15.74% Nov 18, 1999 - Dec 29, 1999
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-14.68% Sep 14, 2018 - Feb 11, 2019