DNLI vs MMSI

Comparison between Denali Therapeutics Inc (DNLI, Company) and Merit Medical Systems Inc (MMSI, Company).

Both DNLI and MMSI are from the Healthcare sector.

5-Year PerformanceMMSI has outperformed DNLI, delivering a return of +3.0% compared to -18.7%

DNLI vs MMSI - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	MMSI(COMPANY)
Market Cap	$4.23B	$4.24B
Max Drawdown	87.74%	68.67%
Sharpe Ratio	1.17	-0.82
5Y Beta	1.50	0.73
Industry	Biotechnology	Medical Instruments & Supplies
P/E Ratio	-7.97	30.30
Forward P/E	N/A	18.05
PEG Ratio	-1.24	2.46
5Y EPS CAGR	N/A	99.24%
Debt to Equity	0.00%	45.19%
Free Cash Flow Yield	-9.97%	5.21%
P/S Ratio	3643.65	2.75
P/B Ratio	4.43	2.62

Market Cap

DNLI

$4.23B

Winner

MMSI

$4.24B

Max Drawdown

DNLI

87.74%

Winner

MMSI

68.67%

Sharpe Ratio

Winner

DNLI

1.17

MMSI

-0.82

5Y Beta

DNLI

1.50

Winner

MMSI

0.73

Industry

DNLI

Biotechnology

MMSI

Medical Instruments & Supplies

P/E Ratio

Winner

DNLI

-7.97

MMSI

30.30

Forward P/E

DNLI

N/A

MMSI

18.05

PEG Ratio

Winner

DNLI

-1.24

MMSI

2.46

5Y EPS CAGR

DNLI

N/A

MMSI

99.24%

Debt to Equity

Winner

DNLI

0.00%

MMSI

45.19%

Free Cash Flow Yield

DNLI

-9.97%

Winner

MMSI

5.21%

P/S Ratio

DNLI

3643.65

Winner

MMSI

2.75

P/B Ratio

DNLI

4.43

Winner

MMSI

2.62

DNLI vs MMSI - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	MMSI
1 month	+24.60%	+9.63%
3 months	+33.54%	+7.59%
6 months	+50.35%	-14.98%
1 year	+67.30%	-22.83%
5 years(CAGR)	-18.68%	+2.98%
10 years(CAGR)	+2.12%	+13.52%
Max(CAGR)	+2.12%	+15.04%

Winner

DNLI

+24.60%

MMSI

+9.63%

Winner

DNLI

+33.54%

MMSI

+7.59%

Winner

DNLI

+50.35%

MMSI

-14.98%

Winner

DNLI

+67.30%

MMSI

-22.83%

5Y(CAGR)

DNLI

-18.68%

Winner

MMSI

+2.98%

10Y(CAGR)

DNLI

+2.12%

Winner

MMSI

+13.52%

Max(CAGR)

DNLI

+2.12%

Winner

MMSI

+15.04%

DNLI vs MMSI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DNLI	MMSI
2026	+57.84%	-15.05%
2025	-20.78%	-8.25%
2024	-4.72%	+26.63%
2023	-22.33%	+9.14%
2022	-41.17%	+10.65%
2021	-37.06%	+13.77%
2020	+411.04%	+76.45%
2019	-9.88%	-41.32%
2018	+28.08%	+28.15%
2017	-27.09%	+64.89%
2016	N/A	+46.73%
2015	N/A	+10.13%
2014	N/A	+14.09%
2013	N/A	+12.27%
2012	N/A	+2.13%
2011	N/A	+4.66%
2010	N/A	-19.85%
2009	N/A	+8.15%
2008	N/A	+26.80%
2007	N/A	-12.58%
2006	N/A	+27.74%
2005	N/A	-18.25%
2004	N/A	-31.45%
2003	N/A	+90.35%
2002	N/A	+35.03%
2001	N/A	+344.76%
2000	N/A	-19.64%
1999	N/A	+19.58%

DNLI vs MMSI Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for MMSI was -68.67%, occurring on Oct 31, 2019. Recovery took 710 trading sessions.

The current DNLI drawdown is -72.55%. The current MMSI drawdown is -33.41%.

Rank	DNLI	MMSI
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-68.67% Oct 3, 2018 - Jul 30, 2021
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-63.64% Mar 24, 2000 - Jul 27, 2001
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-61.24% Jan 5, 2004 - Apr 24, 2015
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-45.32% Jan 30, 2025 - May 11, 2026
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-38.69% Jul 28, 2015 - Dec 8, 2016
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-34.70% Oct 11, 2001 - Jan 3, 2002
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-30.94% Jan 3, 2002 - Apr 8, 2002
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-29.43% Sep 2, 2021 - Dec 12, 2022
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-28.96% Nov 1, 2002 - Jul 24, 2003
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-26.18% Jun 7, 2023 - Jun 28, 2024
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-22.85% Jun 27, 2002 - Oct 3, 2002
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-20.06% Jul 30, 2001 - Aug 13, 2001
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-20.05% Apr 9, 2002 - Jun 18, 2002
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-18.94% Oct 5, 2017 - Jan 16, 2018
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-16.57% Oct 17, 2002 - Oct 30, 2002