MFG vs VRTX

Comparison between Mizuho Financial Group Inc (MFG, Company) and Vertex Pharmaceuticals Inc (VRTX, Company).

MFG is from the Financial Services sector, while VRTX is from the Healthcare sector.

5-Year PerformanceMFG has outperformed VRTX, delivering a return of +28.2% compared to +14.9%

MFG vs VRTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MFG(COMPANY)	VRTX(COMPANY)
Market Cap	$110B	$109B
Max Drawdown	86.75%	91.77%
Sharpe Ratio	1.97	0.04
5Y Beta	1.11	0.51
Industry	Banks - Regional	Biotechnology
P/E Ratio	15.72	25.09
Forward P/E	13.11	22.57
PEG Ratio	0.69	2.11
Dividend Yield	2.26%	N/A
5Y Dividends CAGR	32.63%	N/A
5Y EPS CAGR	13.59%	9.89%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.97%	3.41%
P/S Ratio	0.03	8.88
P/B Ratio	1.44	5.65

Market Cap

Winner

MFG

$110B

VRTX

$109B

Max Drawdown

Winner

MFG

86.75%

VRTX

91.77%

Sharpe Ratio

Winner

MFG

1.97

VRTX

0.04

5Y Beta

MFG

1.11

Winner

VRTX

0.51

Industry

MFG

Banks - Regional

VRTX

Biotechnology

P/E Ratio

Winner

MFG

15.72

VRTX

25.09

Forward P/E

Winner

MFG

13.11

VRTX

22.57

PEG Ratio

Winner

MFG

0.69

VRTX

2.11

Dividend Yield

MFG

2.26%

VRTX

N/A

5Y Dividends CAGR

MFG

32.63%

VRTX

N/A

5Y EPS CAGR

Winner

MFG

13.59%

VRTX

9.89%

Debt to Equity

MFG

0.00%

VRTX

0.00%

Free Cash Flow Yield

MFG

-2.97%

Winner

VRTX

3.41%

P/S Ratio

Winner

MFG

0.03

VRTX

8.88

P/B Ratio

Winner

MFG

1.44

VRTX

5.65

MFG vs VRTX - Historical Returns

Returns include dividend reinvestment.

Period	MFG	VRTX
1 month	-1.25%	-3.18%
3 months	-11.33%	-8.72%
6 months	+31.07%	+4.97%
1 year	+77.28%	+0.05%
5 years(CAGR)	+28.18%	+14.85%
10 years(CAGR)	+14.27%	+17.19%
Max(CAGR)	+0.30%	+14.03%

Winner

MFG

-1.25%

VRTX

-3.18%

MFG

-11.33%

Winner

VRTX

-8.72%

Winner

MFG

+31.07%

VRTX

+4.97%

Winner

MFG

+77.28%

VRTX

+0.05%

5Y(CAGR)

Winner

MFG

+28.18%

VRTX

+14.85%

10Y(CAGR)

MFG

+14.27%

Winner

VRTX

+17.19%

Max(CAGR)

MFG

+0.30%

Winner

VRTX

+14.03%

MFG vs VRTX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MFG	VRTX
2026	+17.27%	-4.93%
2025	+54.62%	+11.73%
2024	+48.52%	-2.00%
2023	+25.67%	+42.26%
2022	+15.29%	+29.77%
2021	+2.43%	-4.28%
2020	-15.11%	+7.70%
2019	+1.31%	+33.44%
2018	-18.03%	+8.37%
2017	+2.64%	+100.11%
2016	-6.13%	-40.05%
2015	+23.94%	+2.24%
2014	-18.45%	+60.91%
2013	+17.89%	+70.22%
2012	+38.55%	+30.00%
2011	-25.70%	-7.72%
2010	+8.69%	-20.82%
2009	-37.15%	+39.62%
2008	-37.49%	+31.23%
2007	-33.09%	-37.05%
2006	-3.03%	+34.12%
2005	N/A	+170.21%
2004	N/A	+0.67%
2003	N/A	-36.74%
2002	N/A	-35.41%
2001	N/A	-61.05%
2000	N/A	+281.33%
1999	N/A	+32.38%

MFG vs VRTX Drawdown Comparison

The maximum drawdown for MFG was -80.58%, occurring on Mar 16, 2020. Recovery took 4776 trading sessions.

The maximum drawdown for VRTX was -91.77%, occurring on Nov 11, 2003. Recovery took 3434 trading sessions.

The current MFG drawdown is -13.88%. The current VRTX drawdown is -16.82%.

Rank	MFG	VRTX
#1	-80.58% Jan 22, 2007 - Jan 14, 2026	-91.77% Nov 2, 2000 - Jul 2, 2014
#2	-24.78% Feb 11, 2026 - Mar 20, 2026	-55.25% Mar 6, 2000 - Jun 16, 2000
#3	-7.78% Nov 14, 2006 - Dec 4, 2006	-49.10% Aug 19, 2015 - Jul 19, 2017
#4	-5.33% Dec 15, 2006 - Jan 22, 2007	-41.60% Jul 20, 2020 - Aug 15, 2022
#5	-4.02% Dec 4, 2006 - Dec 15, 2006	-29.08% Sep 28, 2000 - Oct 25, 2000
#6	-3.83% Nov 8, 2006 - Nov 14, 2006	-29.07% Nov 8, 2024 - Aug 8, 2025
#7	-3.12% Feb 4, 2026 - Feb 6, 2026	-22.82% Jul 12, 2000 - Aug 16, 2000
#8	-2.56% Jan 16, 2026 - Jan 27, 2026	-21.18% Sep 28, 2018 - Jan 18, 2019
#9	-0.58% Jan 27, 2026 - Feb 2, 2026	-19.52% Jan 21, 2000 - Feb 7, 2000
#10	N/A	-19.39% Feb 11, 2020 - Apr 6, 2020
#11	N/A	-17.73% Mar 12, 2018 - Jul 12, 2018
#12	N/A	-17.36% Jul 24, 2017 - Jan 23, 2018
#13	N/A	-15.45% Jan 18, 2019 - Oct 29, 2019
#14	N/A	-15.26% Jan 22, 2015 - Mar 16, 2015
#15	N/A	-14.46% Jul 11, 2014 - Sep 19, 2014