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MESO vs SPY

Comparison between Mesoblast Ltd (MESO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed MESO, delivering a return of +13.3% compared to -0.7%

MESO vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
MESO
$2.02B
Winner
SPY
$735B
Expense Ratio
MESO
N/A
SPY
0.09%
Max Drawdown
MESO
95.66%
Winner
SPY
56.47%
Sharpe Ratio
MESO
0.56
Winner
SPY
1.62
5Y Beta
MESO
1.42
Winner
SPY
1.00
Industry
MESO
Biotechnology
SPY
N/A
P/E Ratio
Winner
MESO
-18.75
SPY
28.99
Forward P/E
MESO
454.55
Winner
SPY
22.37
PEG Ratio
MESO
0.00
SPY
N/A
5Y Dividends CAGR
MESO
N/A
SPY
5.43%
5Y EPS CAGR
MESO
-10.27%
Winner
SPY
26.05%
Debt to Equity
Winner
MESO
21.45%
SPY
32.40%
Free Cash Flow Yield
MESO
-3.01%
SPY
N/A
P/S Ratio
MESO
34.34
Winner
SPY
3.74
P/B Ratio
Winner
MESO
3.65
SPY
5.61

MESO vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
MESO
-11.65%
Winner
SPY
+1.90%
3M
MESO
-11.03%
Winner
SPY
+8.55%
6M
MESO
-21.94%
Winner
SPY
+8.18%
1Y
MESO
+20.16%
Winner
SPY
+25.79%
5Y(CAGR)
MESO
-0.69%
Winner
SPY
+13.32%
10Y(CAGR)
MESO
-0.14%
Winner
SPY
+15.19%
Max(CAGR)
MESO
-1.42%
Winner
SPY
+8.47%

MESO vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearMESOSPY
2026-23.18%+8.26%
2025-12.47%+18.00%
2024+816.67%+25.59%
2023-62.59%+26.72%
2022-41.57%-18.64%
2021-43.60%+30.52%
2020+8.43%+17.28%
2019+64.14%+31.09%
2018-29.45%-5.24%
2017+8.15%+20.78%
2016-13.43%+13.59%
2015-21.58%+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

MESO vs SPY Drawdown Comparison

The maximum drawdown for MESO was -95.66%, occurring on Jan 18, 2024. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current MESO drawdown is -64.79%. The current SPY drawdown is -2.90%.

RankMESOSPY
#1-95.66%
Aug 17, 2020 - Jan 18, 2024		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-72.61%
Apr 26, 2017 - Apr 24, 2020		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-66.41%
Mar 17, 2016 - Apr 11, 2017		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-46.24%
Nov 13, 2015 - Mar 2, 2016		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-34.96%
Aug 10, 2020 - Aug 14, 2020		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-34.82%
Apr 24, 2020 - Aug 5, 2020		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-16.68%
Mar 2, 2016 - Mar 17, 2016		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-3.53%
Apr 20, 2017 - Apr 25, 2017		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-3.06%
Apr 11, 2017 - Apr 18, 2017		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-1.46%
Aug 5, 2020 - Aug 7, 2020		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-0.80%
Apr 18, 2017 - Apr 20, 2017		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between MESO and SPY is -0.04 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.04
-101

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