MDGL vs LFUS

Comparison between Madrigal Pharmaceuticals Inc (MDGL, Company) and Littelfuse Inc (LFUS, Company).

MDGL is from the Healthcare sector, while LFUS is from the Technology sector.

5-Year PerformanceMDGL has outperformed LFUS, delivering a return of +38.2% compared to +14.7%

MDGL vs LFUS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDGL(COMPANY)	LFUS(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	98.40%	82.44%
Sharpe Ratio	1.43	2.06
5Y Beta	0.73	1.54
Industry	Biotechnology	Electronic Components
P/E Ratio	-37.50	46.97
Forward P/E	666.67	33.00
PEG Ratio	N/A	2.77
Dividend Yield	N/A	0.60%
5Y Dividends CAGR	N/A	14.02%
5Y EPS CAGR	23.26%	6.84%
Debt to Equity	62.62%	25.12%
Free Cash Flow Yield	-2.33%	3.35%

Market Cap

Winner

MDGL

$12B

LFUS

$12B

Max Drawdown

MDGL

98.40%

Winner

LFUS

82.44%

Sharpe Ratio

MDGL

1.43

Winner

LFUS

2.06

5Y Beta

Winner

MDGL

0.73

LFUS

1.54

Industry

MDGL

Biotechnology

LFUS

Electronic Components

P/E Ratio

Winner

MDGL

-37.50

LFUS

46.97

Forward P/E

MDGL

666.67

Winner

LFUS

33.00

PEG Ratio

MDGL

N/A

LFUS

2.77

Dividend Yield

MDGL

N/A

LFUS

0.60%

5Y Dividends CAGR

MDGL

N/A

LFUS

14.02%

5Y EPS CAGR

Winner

MDGL

23.26%

LFUS

6.84%

Debt to Equity

MDGL

62.62%

Winner

LFUS

25.12%

Free Cash Flow Yield

MDGL

-2.33%

Winner

LFUS

3.35%

MDGL vs LFUS - Historical Returns

Returns include dividend reinvestment.

Period	MDGL	LFUS
1 month	-1.45%	+0.70%
3 months	+14.54%	+31.76%
6 months	-15.44%	+78.65%
1 year	+78.88%	+109.56%
5 years(CAGR)	+38.20%	+14.68%
10 years(CAGR)	+47.07%	+15.95%
Max(CAGR)	+2.46%	+12.76%

MDGL

-1.45%

Winner

LFUS

+0.70%

MDGL

+14.54%

Winner

LFUS

+31.76%

MDGL

-15.44%

Winner

LFUS

+78.65%

MDGL

+78.88%

Winner

LFUS

+109.56%

5Y(CAGR)

Winner

MDGL

+38.20%

LFUS

+14.68%

10Y(CAGR)

Winner

MDGL

+47.07%

LFUS

+15.95%

Max(CAGR)

MDGL

+2.46%

Winner

LFUS

+12.76%

MDGL vs LFUS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MDGL	LFUS
2026	-14.16%	+77.28%
2025	+85.59%	+9.09%
2024	+36.02%	-9.02%
2023	-18.93%	+21.19%
2022	+222.07%	-29.67%
2021	-22.80%	+25.78%
2020	+22.60%	+32.98%
2019	-18.06%	+13.61%
2018	+15.71%	-12.83%
2017	+475.13%	+32.24%
2016	+28.97%	+48.51%
2015	-87.74%	+13.16%
2014	-49.62%	+7.22%
2013	-45.64%	+49.56%
2012	+84.46%	+38.70%
2011	-24.56%	-10.07%
2010	+10.87%	+40.62%
2009	-17.99%	+86.16%
2008	-3.62%	-51.02%
2007	-26.29%	+5.24%
2006	N/A	+14.10%
2005	N/A	-19.02%
2004	N/A	+19.07%
2003	N/A	+66.11%
2002	N/A	-33.80%
2001	N/A	+4.96%
2000	N/A	+16.86%
1999	N/A	+9.08%

MDGL vs LFUS Drawdown Comparison

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The maximum drawdown for LFUS was -82.44%, occurring on Mar 9, 2009. Recovery took 2646 trading sessions.

The current MDGL drawdown is -15.44%. The current LFUS drawdown is -5.20%.

Rank	MDGL	LFUS
#1	-98.40% Jan 28, 2013 - Aug 22, 2025	-82.44% Jun 29, 2000 - Jan 6, 2011
#2	-87.64% Oct 5, 2007 - Jan 22, 2013	-54.17% Jun 20, 2018 - Nov 16, 2020
#3	-51.43% Jun 4, 2007 - Oct 4, 2007	-53.29% Nov 17, 2021 - Jan 29, 2026
#4	-29.36% Dec 22, 2025 - Mar 3, 2026	-40.12% May 2, 2011 - Apr 2, 2012
#5	-18.88% Feb 9, 2007 - Jun 4, 2007	-21.61% Apr 2, 2012 - Jan 23, 2013
#6	-10.10% Sep 30, 2025 - Nov 5, 2025	-19.75% Feb 25, 2026 - Apr 10, 2026
#7	-9.42% Nov 26, 2025 - Dec 22, 2025	-18.54% Apr 16, 2014 - Nov 3, 2014
#8	-8.01% Sep 8, 2025 - Sep 30, 2025	-18.17% Mar 2, 2015 - Nov 2, 2015
#9	-4.91% Nov 11, 2025 - Nov 17, 2025	-17.23% Nov 9, 2015 - Feb 23, 2016
#10	-4.32% Jan 23, 2013 - Jan 25, 2013	-17.03% Mar 29, 2000 - May 30, 2000
#11	-3.02% Nov 18, 2025 - Nov 24, 2025	-16.40% Mar 16, 2018 - Jun 6, 2018
#12	-1.52% Aug 29, 2025 - Sep 8, 2025	-15.89% Jan 20, 2021 - Aug 27, 2021
#13	-0.59% Aug 22, 2025 - Aug 26, 2025	-15.46% Nov 12, 1999 - Dec 30, 1999
#14	N/A	-13.00% Mar 29, 2016 - Jul 27, 2016
#15	N/A	-12.91% Oct 24, 2017 - Nov 21, 2017