StockComparison Logo
vs

KZR vs SPY

Comparison between Kezar Life Sciences Inc (KZR, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed KZR, delivering a return of +13.3% compared to -32.1%

KZR vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
KZR
$54M
Winner
SPY
$735B
Expense Ratio
KZR
N/A
SPY
0.09%
Max Drawdown
KZR
98.91%
Winner
SPY
56.47%
Sharpe Ratio
KZR
1.08
Winner
SPY
1.62
5Y Beta
KZR
N/A
SPY
1.00
Industry
KZR
Biotechnology
SPY
N/A
P/E Ratio
Winner
KZR
-1.18
SPY
28.99
Forward P/E
KZR
N/A
SPY
22.37
5Y Dividends CAGR
KZR
N/A
SPY
5.43%
5Y EPS CAGR
KZR
-8.41%
Winner
SPY
26.05%
Debt to Equity
Winner
KZR
0.00%
SPY
32.40%
Free Cash Flow Yield
KZR
-78.19%
SPY
N/A
P/S Ratio
KZR
N/A
SPY
3.74
P/B Ratio
KZR
N/A
SPY
5.61

KZR vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
KZR
-1.09%
Winner
SPY
+1.90%
3M
Winner
KZR
+14.98%
SPY
+8.55%
6M
Winner
KZR
+17.96%
SPY
+8.18%
1Y
Winner
KZR
+72.34%
SPY
+25.79%
5Y(CAGR)
KZR
-32.10%
Winner
SPY
+13.32%
10Y(CAGR)
KZR
N/A
SPY
+15.19%
Max(CAGR)
KZR
-33.28%
Winner
SPY
+8.47%

KZR vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearKZRSPY
2026+15.90%+8.26%
2025-4.26%+18.00%
2024-29.26%+25.59%
2023-86.33%+26.72%
2022-55.47%-18.64%
2021+216.67%+30.52%
2020+45.81%+17.28%
2019-82.37%+31.09%
2018+32.96%-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

KZR vs SPY Drawdown Comparison

The maximum drawdown for KZR was -98.91%, occurring on Sep 29, 2025. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current KZR drawdown is -97.78%. The current SPY drawdown is -2.90%.

RankKZRSPY
#1-98.91%
Dec 13, 2018 - Sep 29, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-12.87%
Jun 22, 2018 - Sep 6, 2018		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-10.75%
Oct 22, 2018 - Nov 12, 2018		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-9.94%
Nov 30, 2018 - Dec 13, 2018		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-9.16%
Nov 12, 2018 - Nov 29, 2018		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-6.39%
Sep 12, 2018 - Sep 28, 2018		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-5.85%
Oct 10, 2018 - Oct 15, 2018		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-5.60%
Sep 28, 2018 - Oct 8, 2018		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-3.28%
Oct 15, 2018 - Oct 18, 2018		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-1.87%
Sep 7, 2018 - Sep 11, 2018		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between KZR and SPY is -0.61 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.61
-101

Select Stocks to Compare

Popular: KZR vs SPY

More Comparisons

Compare with similar stocks