KZR vs MDAI

Comparison between Kezar Life Sciences Inc (KZR, Company) and Spectral AI Inc - Class A (MDAI, Company).

Both KZR and MDAI are from the Healthcare sector.

5-Year PerformanceMDAI has outperformed KZR, delivering a return of -29.5% compared to -32.1%

KZR vs MDAI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KZR(COMPANY)	MDAI(COMPANY)
Market Cap	$54M	$54M
Max Drawdown	98.91%	93.49%
Sharpe Ratio	1.08	-0.29
5Y Beta	N/A	1.08
Industry	Biotechnology	Medical Devices
P/E Ratio	-1.18	-3.30
Forward P/E	N/A	52.36
PEG Ratio	N/A	-0.33
5Y EPS CAGR	-8.41%	N/A
Debt to Equity	0.00%	-51.10%
Free Cash Flow Yield	-78.19%	-22.58%
P/S Ratio	N/A	3.18
P/B Ratio	N/A	26.08

Market Cap

KZR

$54M

Winner

MDAI

$54M

Max Drawdown

KZR

98.91%

Winner

MDAI

93.49%

Sharpe Ratio

Winner

KZR

1.08

MDAI

-0.29

5Y Beta

KZR

N/A

MDAI

1.08

Industry

KZR

Biotechnology

MDAI

Medical Devices

P/E Ratio

KZR

-1.18

Winner

MDAI

-3.30

Forward P/E

KZR

N/A

MDAI

52.36

PEG Ratio

KZR

N/A

MDAI

-0.33

5Y EPS CAGR

KZR

-8.41%

MDAI

N/A

Debt to Equity

KZR

0.00%

Winner

MDAI

-51.10%

Free Cash Flow Yield

KZR

-78.19%

Winner

MDAI

-22.58%

P/S Ratio

KZR

N/A

MDAI

3.18

P/B Ratio

KZR

N/A

MDAI

26.08

KZR vs MDAI - Historical Returns

Returns include dividend reinvestment.

Period	KZR	MDAI
1 month	-1.09%	-2.89%
3 months	+14.98%	-6.15%
6 months	+17.96%	+9.09%
1 year	+72.34%	-31.15%
5 years(CAGR)	-32.10%	-29.53%
Max(CAGR)	-33.28%	-28.21%

Winner

KZR

-1.09%

MDAI

-2.89%

Winner

KZR

+14.98%

MDAI

-6.15%

Winner

KZR

+17.96%

MDAI

+9.09%

Winner

KZR

+72.34%

MDAI

-31.15%

5Y(CAGR)

KZR

-32.10%

Winner

MDAI

-29.53%

Max(CAGR)

KZR

-33.28%

Winner

MDAI

-28.21%

KZR vs MDAI - Annual Returns (2018 - 2026)

Returns include dividend reinvestment.

Year	KZR	MDAI
2026	+15.90%	+15.86%
2025	-4.26%	-47.99%
2024	-29.26%	+11.86%
2023	-86.33%	-75.52%
2022	-55.47%	+2.85%
2021	+216.67%	+1.13%
2020	+45.81%	N/A
2019	-82.37%	N/A
2018	+32.96%	N/A

KZR vs MDAI Drawdown Comparison

The maximum drawdown for KZR was -98.91%, occurring on Sep 29, 2025. This drawdown has not yet recovered.

The maximum drawdown for MDAI was -93.49%, occurring on Sep 24, 2024. This drawdown has not yet recovered.

The current KZR drawdown is -97.78%. The current MDAI drawdown is -88.36%.

Rank	KZR	MDAI
#1	-98.91% Dec 13, 2018 - Sep 29, 2025	-93.49% Sep 7, 2023 - Sep 24, 2024
#2	-12.87% Jun 22, 2018 - Sep 6, 2018	-29.39% Apr 14, 2023 - Sep 7, 2023
#3	-10.75% Oct 22, 2018 - Nov 12, 2018	-6.99% Apr 12, 2023 - Apr 14, 2023
#4	-9.94% Nov 30, 2018 - Dec 13, 2018	-2.73% Jan 5, 2023 - Apr 11, 2023
#5	-9.16% Nov 12, 2018 - Nov 29, 2018	-2.68% Dec 19, 2022 - Dec 23, 2022
#6	-6.39% Sep 12, 2018 - Sep 28, 2018	-2.39% May 14, 2021 - Nov 17, 2021
#7	-5.85% Oct 10, 2018 - Oct 15, 2018	-1.86% Dec 28, 2022 - Jan 5, 2023
#8	-5.60% Sep 28, 2018 - Oct 8, 2018	-1.62% Nov 30, 2021 - Oct 13, 2022
#9	-3.28% Oct 15, 2018 - Oct 18, 2018	-1.02% May 4, 2021 - May 14, 2021
#10	-1.87% Sep 7, 2018 - Sep 11, 2018	-0.92% Apr 7, 2021 - May 3, 2021
#11	N/A	-0.49% Dec 23, 2022 - Dec 28, 2022
#12	N/A	-0.40% Oct 26, 2022 - Nov 9, 2022
#13	N/A	-0.20% Nov 29, 2022 - Dec 19, 2022
#14	N/A	-0.10% Nov 19, 2021 - Nov 24, 2021
#15	N/A	-0.10% Oct 14, 2022 - Oct 21, 2022