KRYS vs SPY
Comparison between Krystal Biotech Inc (KRYS, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceKRYS has outperformed SPY, delivering a return of +36.0% compared to +14.0%
KRYS vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
KRYS
$9.20B
Winner
SPY
$735B
Expense Ratio
KRYS
N/A
SPY
0.09%
Max Drawdown
Winner
KRYS
53.42%
SPY
56.47%
Sharpe Ratio
Winner
KRYS
2.33
SPY
1.88
5Y Beta
Winner
KRYS
0.96
SPY
1.00
Industry
KRYS
Biotechnology
SPY
N/A
P/E Ratio
KRYS
40.47
Winner
SPY
28.46
Forward P/E
KRYS
44.84
Winner
SPY
21.99
PEG Ratio
KRYS
0.51
SPY
N/A
5Y Dividends CAGR
KRYS
N/A
SPY
5.43%
5Y EPS CAGR
KRYS
N/A
SPY
25.20%
Debt to Equity
Winner
KRYS
0.00%
SPY
33.33%
Free Cash Flow Yield
KRYS
2.58%
SPY
N/A
P/S Ratio
KRYS
22.19
Winner
SPY
3.65
P/B Ratio
KRYS
7.06
Winner
SPY
5.50
KRYS vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
Winner
KRYS
+17.15%
SPY
+7.73%
3M
Winner
KRYS
+14.41%
SPY
+10.05%
6M
Winner
KRYS
+53.42%
SPY
+11.98%
1Y
Winner
KRYS
+140.73%
SPY
+28.79%
5Y(CAGR)
Winner
KRYS
+36.03%
SPY
+13.98%
10Y(CAGR)
Winner
KRYS
+48.04%
SPY
+15.71%
Max(CAGR)
Winner
KRYS
+48.04%
SPY
+8.55%
KRYS vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | KRYS | SPY |
|---|---|---|
| 2026 | +28.10% | +9.82% |
| 2025 | +57.53% | +18.00% |
| 2024 | +25.37% | +25.59% |
| 2023 | +56.58% | +26.72% |
| 2022 | +9.86% | -18.64% |
| 2021 | +17.72% | +30.52% |
| 2020 | +5.28% | +17.28% |
| 2019 | +142.47% | +31.09% |
| 2018 | +126.36% | -5.24% |
| 2017 | -1.13% | +20.78% |
| 2016 | N/A | +13.59% |
| 2015 | N/A | +1.31% |
| 2014 | N/A | +14.56% |
| 2013 | N/A | +29.00% |
| 2012 | N/A | +14.17% |
| 2011 | N/A | +0.85% |
| 2010 | N/A | +13.14% |
| 2009 | N/A | +22.67% |
| 2008 | N/A | -36.25% |
| 2007 | N/A | +5.32% |
| 2006 | N/A | +13.85% |
| 2005 | N/A | +5.32% |
| 2004 | N/A | +10.75% |
| 2003 | N/A | +24.18% |
| 2002 | N/A | -22.42% |
| 2001 | N/A | -10.13% |
| 2000 | N/A | -8.84% |
| 1999 | N/A | +8.61% |
KRYS vs SPY Drawdown Comparison
The maximum drawdown for KRYS was -53.42%, occurring on Nov 26, 2021. Recovery took 190 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
| Rank | KRYS | SPY |
|---|---|---|
| #1 | -53.42% Mar 1, 2021 - Nov 29, 2021 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -46.65% Feb 12, 2020 - Jan 8, 2021 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -44.55% Nov 29, 2021 - Apr 13, 2023 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -42.26% Jul 26, 2024 - Nov 24, 2025 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -35.34% Jul 22, 2019 - Nov 13, 2019 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -28.43% Sep 11, 2018 - Oct 16, 2018 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -27.86% Dec 13, 2019 - Feb 12, 2020 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -26.81% Oct 18, 2017 - Mar 16, 2018 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -26.58% Jan 8, 2019 - Mar 25, 2019 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -26.34% Jun 13, 2023 - Jan 22, 2024 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -24.99% May 14, 2019 - Jun 24, 2019 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -24.14% Oct 16, 2018 - Nov 30, 2018 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -23.42% Mar 16, 2018 - Jun 6, 2018 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -19.86% Nov 30, 2018 - Jan 7, 2019 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | -17.56% Jan 22, 2024 - Feb 26, 2024 | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between KRYS and SPY is 0.94 which considered as a very strong positive correlation - the stocks move almost identically together.
0.94
-101
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