KPTI vs EDAP

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and EDAP TMS S.A. (EDAP, Company).

Both KPTI and EDAP are from the Healthcare sector.

5-Year PerformanceEDAP has outperformed KPTI, delivering a return of -8.5% compared to -44.3%

KPTI vs EDAP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	EDAP(COMPANY)
Market Cap	$162M	$162M
Max Drawdown	99.50%	95.38%
Sharpe Ratio	1.05	1.41
5Y Beta	0.83	0.73
Industry	Biotechnology	Medical Distribution
P/E Ratio	-0.49	-4.70
Forward P/E	N/A	38.91
PEG Ratio	-0.00	-0.06
5Y EPS CAGR	-18.43%	N/A
Debt to Equity	0.00%	11.18%
Free Cash Flow Yield	-36.52%	-8.71%
P/S Ratio	1.08	N/A
P/B Ratio	12.05	N/A

Market Cap

Winner

KPTI

$162M

EDAP

$162M

Max Drawdown

KPTI

99.50%

Winner

EDAP

95.38%

Sharpe Ratio

KPTI

1.05

Winner

EDAP

1.41

5Y Beta

KPTI

0.83

Winner

EDAP

0.73

Industry

KPTI

Biotechnology

EDAP

Medical Distribution

P/E Ratio

KPTI

-0.49

Winner

EDAP

-4.70

Forward P/E

KPTI

N/A

EDAP

38.91

PEG Ratio

KPTI

-0.00

Winner

EDAP

-0.06

5Y EPS CAGR

KPTI

-18.43%

EDAP

N/A

Debt to Equity

Winner

KPTI

0.00%

EDAP

11.18%

Free Cash Flow Yield

KPTI

-36.52%

Winner

EDAP

-8.71%

P/S Ratio

KPTI

1.08

EDAP

N/A

P/B Ratio

KPTI

12.05

EDAP

N/A

KPTI vs EDAP - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	EDAP
1 month	-26.53%	+30.51%
3 months	-18.97%	+5.37%
6 months	+7.59%	+80.00%
1 year	+45.88%	+141.34%
5 years(CAGR)	-44.33%	-8.54%
10 years(CAGR)	-23.66%	+2.13%
Max(CAGR)	-24.22%	+4.40%

KPTI

-26.53%

Winner

EDAP

+30.51%

KPTI

-18.97%

Winner

EDAP

+5.37%

KPTI

+7.59%

Winner

EDAP

+80.00%

KPTI

+45.88%

Winner

EDAP

+141.34%

5Y(CAGR)

KPTI

-44.33%

Winner

EDAP

-8.54%

10Y(CAGR)

KPTI

-23.66%

Winner

EDAP

+2.13%

Max(CAGR)

KPTI

-24.22%

Winner

EDAP

+4.40%

KPTI vs EDAP - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	KPTI	EDAP
2026	-1.39%	+27.06%
2025	-39.54%	+37.08%
2024	-24.96%	-58.38%
2023	-73.47%	-49.43%
2022	-52.11%	+86.04%
2021	-62.00%	+16.99%
2020	-17.31%	+16.44%
2019	+100.52%	+136.90%
2018	-5.54%	-35.29%
2017	-0.41%	-14.07%
2016	-30.16%	-17.38%
2015	-65.12%	+68.57%
2014	+62.67%	-20.48%
2013	+42.80%	+40.48%
2012	N/A	+22.16%
2011	N/A	-66.53%
2010	N/A	+111.24%
2009	N/A	+65.66%
2008	N/A	-70.00%
2007	N/A	-16.67%
2006	N/A	+7.28%
2005	N/A	+50.80%
2004	N/A	+109.94%
2003	N/A	+49.17%
2002	N/A	-46.67%
2001	N/A	+201.33%
2000	N/A	-35.00%
1999	N/A	+0.00%

KPTI vs EDAP Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for EDAP was -95.38%, occurring on Apr 21, 2009. This drawdown has not yet recovered.

The current KPTI drawdown is -99.00%. The current EDAP drawdown is -79.20%.

Rank	KPTI	EDAP
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-95.38% Mar 30, 2006 - Apr 21, 2009
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-79.17% Feb 14, 2000 - May 25, 2001
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-64.06% May 25, 2001 - Apr 28, 2004
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-53.57% Nov 16, 1999 - Jan 31, 2000
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	-48.13% Apr 28, 2004 - Dec 28, 2004
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	-35.23% Feb 1, 2005 - Dec 30, 2005
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	-30.93% Feb 1, 2000 - Feb 14, 2000
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	-16.67% Nov 4, 1999 - Nov 16, 1999
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	-15.76% Jan 23, 2006 - Feb 28, 2006
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	-7.82% Jan 9, 2006 - Jan 11, 2006
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	-6.86% Mar 6, 2006 - Mar 10, 2006
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	-6.58% Dec 31, 2004 - Jan 14, 2005
#13	N/A	-5.49% Mar 14, 2006 - Mar 16, 2006
#14	N/A	-4.70% Mar 17, 2006 - Mar 22, 2006
#15	N/A	-3.01% Dec 30, 2005 - Jan 4, 2006

Correlation

Correlation between KPTI and EDAP is -0.31 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.31

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