IONS vs WBS

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Webster Financial Corp (WBS, Company).

IONS is from the Healthcare sector, while WBS is from the Financial Services sector.

5-Year PerformanceIONS has outperformed WBS, delivering a return of +14.7% compared to +10.4%

IONS vs WBS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	WBS(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	91.72%	94.25%
Sharpe Ratio	1.73	1.57
5Y Beta	0.73	1.26
Industry	Biotechnology	Banks - Regional
P/E Ratio	-69.58	12.02
Forward P/E	90.91	11.49
PEG Ratio	-1.47	0.33
Dividend Yield	N/A	2.14%
5Y Dividends CAGR	N/A	4.56%
5Y EPS CAGR	-21.44%	14.90%
Debt to Equity	88.01%	7.71%
Free Cash Flow Yield	-7.98%	9.87%
P/S Ratio	11.72	N/A
P/B Ratio	25.08	N/A

Market Cap

Winner

IONS

$12B

WBS

$12B

Max Drawdown

Winner

IONS

91.72%

WBS

94.25%

Sharpe Ratio

Winner

IONS

1.73

WBS

1.57

5Y Beta

Winner

IONS

0.73

WBS

1.26

Industry

IONS

Biotechnology

WBS

Banks - Regional

P/E Ratio

Winner

IONS

-69.58

WBS

12.02

Forward P/E

IONS

90.91

Winner

WBS

11.49

PEG Ratio

Winner

IONS

-1.47

WBS

0.33

Dividend Yield

IONS

N/A

WBS

2.14%

5Y Dividends CAGR

IONS

N/A

WBS

4.56%

5Y EPS CAGR

IONS

-21.44%

Winner

WBS

14.90%

Debt to Equity

IONS

88.01%

Winner

WBS

7.71%

Free Cash Flow Yield

IONS

-7.98%

Winner

WBS

9.87%

P/S Ratio

IONS

11.72

WBS

N/A

P/B Ratio

IONS

25.08

WBS

N/A

IONS vs WBS - Historical Returns

Returns include dividend reinvestment.

Period	IONS	WBS
1 month	+2.47%	+4.60%
3 months	+2.74%	+10.13%
6 months	-3.59%	+18.50%
1 year	+105.56%	+51.51%
5 years(CAGR)	+14.67%	+10.42%
10 years(CAGR)	+12.71%	+11.20%
Max(CAGR)	+7.53%	+6.28%

IONS

+2.47%

Winner

WBS

+4.60%

IONS

+2.74%

Winner

WBS

+10.13%

IONS

-3.59%

Winner

WBS

+18.50%

Winner

IONS

+105.56%

WBS

+51.51%

5Y(CAGR)

Winner

IONS

+14.67%

WBS

+10.42%

10Y(CAGR)

Winner

IONS

+12.71%

WBS

+11.20%

Max(CAGR)

Winner

IONS

+7.53%

WBS

+6.28%

IONS vs WBS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	WBS
2026	-6.73%	+18.83%
2025	+128.05%	+18.15%
2024	-33.88%	+11.36%
2023	+34.62%	+12.53%
2022	+15.86%	-15.39%
2021	-46.41%	+37.28%
2020	-7.14%	-16.99%
2019	+12.35%	+9.59%
2018	+9.77%	-10.81%
2017	+6.25%	+5.98%
2016	-22.45%	+54.74%
2015	+0.58%	+17.95%
2014	+54.85%	+8.87%
2013	+268.21%	+50.00%
2012	+44.00%	-1.43%
2011	-29.93%	+4.02%
2010	-10.20%	+57.96%
2009	-23.22%	-13.80%
2008	-7.80%	-54.09%
2007	+44.10%	-32.59%
2006	+111.81%	+5.12%
2005	-9.66%	-3.58%
2004	-13.36%	+13.58%
2003	-4.97%	+31.02%
2002	-68.69%	+12.07%
2001	+130.55%	+15.67%
2000	+77.49%	+25.59%
1999	-44.34%	-16.60%

IONS vs WBS Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for WBS was -93.72%, occurring on Mar 6, 2009. Recovery took 2450 trading sessions.

The current IONS drawdown is -14.09%.

Rank	IONS	WBS
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-93.72% Feb 20, 2007 - Nov 9, 2016
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-71.99% Jul 23, 2018 - Jan 6, 2022
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-47.90% Jan 11, 2022 - Nov 6, 2024
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-33.07% Nov 25, 2024 - Aug 26, 2025
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-29.59% Nov 3, 1999 - Dec 22, 2000
#6	-28.35% Jul 12, 2013 - Sep 19, 2013	-24.02% Aug 16, 2001 - Mar 15, 2002
#7	-20.89% Sep 23, 2013 - Nov 27, 2013	-22.89% May 2, 2002 - Jul 8, 2003
#8	-19.78% Jan 12, 2015 - Mar 19, 2015	-21.59% Mar 1, 2017 - Nov 29, 2017
#9	-19.45% Feb 6, 2026 - Mar 24, 2026	-17.15% Mar 9, 2004 - Nov 11, 2004
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-14.49% Dec 1, 2004 - Dec 26, 2006
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-14.02% Sep 4, 2025 - Dec 5, 2025
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-12.77% Feb 13, 2001 - Apr 19, 2001
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-11.82% Jan 12, 2018 - Apr 20, 2018
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-8.91% Feb 25, 2026 - Jun 12, 2026
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-8.29% Jul 14, 2003 - Sep 4, 2003

Correlation

Correlation between IONS and WBS is 0.67 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.67

-101

Dividend Comparison (1999 - 2026)

IONS vs WBS dividend yield comparison.

Year	IONS	WBS
2026	0.00%	1.07%
2025	0.00%	2.54%
2024	0.00%	2.90%
2023	0.00%	3.15%
2022	0.00%	3.38%
2021	0.00%	2.87%
2020	0.00%	3.80%
2019	0.00%	2.87%
2018	0.00%	2.54%
2017	0.00%	1.83%
2016	0.00%	1.81%
2015	0.00%	2.39%
2014	0.00%	2.31%
2013	0.00%	1.76%
2012	0.00%	1.70%
2011	0.00%	0.78%
2010	0.00%	0.20%
2009	0.00%	0.34%
2008	0.00%	8.71%
2007	0.00%	3.66%
2006	0.00%	2.18%
2005	0.00%	2.09%
2004	0.00%	1.78%
2003	0.00%	1.79%
2002	0.00%	2.13%
2001	0.00%	1.59%
2000	4.85%	1.62%
1999	3.52%	0.00%