IONS vs ACGLO

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Arch Capital Group Ltd (ACGLO, Company).

IONS is from the Healthcare sector, while ACGLO is from the Financial Services sector.

5-Year PerformanceIONS has outperformed ACGLO, delivering a return of +14.1% compared to -0.6%

IONS vs ACGLO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	ACGLO(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	91.72%	37.01%
Sharpe Ratio	1.65	-0.31
5Y Beta	0.73	0.21
Industry	Biotechnology	Insurance - Diversified
P/E Ratio	-69.58	4.44
Forward P/E	90.91	N/A
PEG Ratio	-1.47	N/A
5Y Dividends CAGR	N/A	4.56%
5Y EPS CAGR	-21.44%	N/A
Debt to Equity	88.01%	N/A
Free Cash Flow Yield	-7.98%	N/A
P/S Ratio	11.72	0.61
P/B Ratio	25.08	N/A

Market Cap

Winner

IONS

$12B

ACGLO

$12B

Max Drawdown

IONS

91.72%

Winner

ACGLO

37.01%

Sharpe Ratio

Winner

IONS

1.65

ACGLO

-0.31

5Y Beta

IONS

0.73

Winner

ACGLO

0.21

Industry

IONS

Biotechnology

ACGLO

Insurance - Diversified

P/E Ratio

Winner

IONS

-69.58

ACGLO

4.44

Forward P/E

IONS

90.91

ACGLO

N/A

PEG Ratio

IONS

-1.47

ACGLO

N/A

5Y Dividends CAGR

IONS

N/A

ACGLO

4.56%

5Y EPS CAGR

IONS

-21.44%

ACGLO

N/A

Debt to Equity

IONS

88.01%

ACGLO

N/A

Free Cash Flow Yield

IONS

-7.98%

ACGLO

N/A

P/S Ratio

IONS

11.72

Winner

ACGLO

0.61

P/B Ratio

IONS

25.08

ACGLO

N/A

IONS vs ACGLO - Historical Returns

Returns include dividend reinvestment.

Period	IONS	ACGLO
1 month	-3.37%	-4.73%
3 months	+1.29%	-4.17%
6 months	-9.34%	-5.31%
1 year	+105.71%	+0.32%
5 years(CAGR)	+14.07%	-0.60%
10 years(CAGR)	+13.07%	+2.88%
Max(CAGR)	+7.47%	+2.88%

Winner

IONS

-3.37%

ACGLO

-4.73%

Winner

IONS

+1.29%

ACGLO

-4.17%

IONS

-9.34%

Winner

ACGLO

-5.31%

Winner

IONS

+105.71%

ACGLO

+0.32%

5Y(CAGR)

Winner

IONS

+14.07%

ACGLO

-0.60%

10Y(CAGR)

Winner

IONS

+13.07%

ACGLO

+2.88%

Max(CAGR)

Winner

IONS

+7.47%

ACGLO

+2.88%

IONS vs ACGLO - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	ACGLO
2026	-8.03%	-4.49%
2025	+128.05%	-0.18%
2024	-33.88%	-4.97%
2023	+34.62%	+23.39%
2022	+15.86%	-15.90%
2021	-46.41%	+3.21%
2020	-7.14%	+6.68%
2019	+12.35%	+30.87%
2018	+9.77%	-14.15%
2017	+6.25%	+4.14%
2016	-22.45%	N/A
2015	+0.58%	N/A
2014	+54.85%	N/A
2013	+268.21%	N/A
2012	+44.00%	N/A
2011	-29.93%	N/A
2010	-10.20%	N/A
2009	-23.22%	N/A
2008	-7.80%	N/A
2007	+44.10%	N/A
2006	+111.81%	N/A
2005	-9.66%	N/A
2004	-13.36%	N/A
2003	-4.97%	N/A
2002	-68.69%	N/A
2001	+130.55%	N/A
2000	+77.49%	N/A
1999	-44.34%	N/A

IONS vs ACGLO Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for ACGLO was -36.08%, occurring on Mar 19, 2020. Recovery took 113 trading sessions.

The current IONS drawdown is -15.29%. The current ACGLO drawdown is -10.89%.

Rank	IONS	ACGLO
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-36.08% Feb 18, 2020 - Jul 29, 2020
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-19.59% Aug 2, 2022 - Dec 20, 2023
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-17.68% Jan 19, 2018 - Mar 29, 2019
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-15.88% Jun 21, 2021 - Aug 2, 2022
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-13.12% Sep 19, 2024 - Apr 11, 2025
#6	-28.35% Jul 12, 2013 - Sep 19, 2013	-7.73% Mar 8, 2024 - Sep 12, 2024
#7	-20.89% Sep 23, 2013 - Nov 27, 2013	-4.22% Dec 15, 2020 - Mar 25, 2021
#8	-19.78% Jan 12, 2015 - Mar 19, 2015	-3.32% Dec 29, 2023 - Feb 23, 2024
#9	-19.45% Feb 6, 2026 - Mar 24, 2026	-3.31% Apr 8, 2021 - Jun 11, 2021
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-3.21% Sep 15, 2020 - Oct 9, 2020
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-3.20% Oct 16, 2019 - Dec 18, 2019
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-2.52% Oct 15, 2020 - Nov 4, 2020
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-2.35% Aug 22, 2019 - Sep 12, 2019
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-1.77% Apr 17, 2019 - Jun 11, 2019
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-1.71% Jul 31, 2019 - Aug 15, 2019

Correlation

Correlation between IONS and ACGLO is -0.15 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.15

-101

Dividend Comparison (1999 - 2026)

IONS vs ACGLO dividend yield comparison.

Year	IONS	ACGLO
2026	0.00%	1.76%
2025	0.00%	6.72%
2024	0.00%	6.42%
2023	0.00%	5.72%
2022	0.00%	6.71%
2021	0.00%	5.30%
2020	0.00%	5.14%
2019	0.00%	5.28%
2018	0.00%	6.70%
2017	0.00%	2.00%
2000	4.85%	0.00%
1999	3.52%	0.00%