IONS vs UHS

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Universal Health Services Inc - Class B (UHS, Company).

Both IONS and UHS are from the Healthcare sector.

5-Year PerformanceIONS has outperformed UHS, delivering a return of +8.9% compared to -0.2%

IONS vs UHS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	UHS(COMPANY)
Market Cap	$9.08B	$9.04B
Max Drawdown	91.72%	56.43%
Sharpe Ratio	0.66	-0.60
5Y Beta	0.66	0.54
Industry	Biotechnology	Medical Care Facilities
P/E Ratio	-51.94	6.73
Forward P/E	90.91	6.49
PEG Ratio	-1.10	0.13
Dividend Yield	N/A	0.52%
5Y Dividends CAGR	N/A	14.87%
5Y EPS CAGR	-21.44%	18.25%
Debt to Equity	88.01%	63.07%
Free Cash Flow Yield	-10.70%	10.10%

Market Cap

Winner

IONS

$9.08B

UHS

$9.04B

Max Drawdown

IONS

91.72%

Winner

UHS

56.43%

Sharpe Ratio

Winner

IONS

0.66

UHS

-0.60

5Y Beta

IONS

0.66

Winner

UHS

0.54

Industry

IONS

Biotechnology

UHS

Medical Care Facilities

P/E Ratio

Winner

IONS

-51.94

UHS

6.73

Forward P/E

IONS

90.91

Winner

UHS

6.49

PEG Ratio

Winner

IONS

-1.10

UHS

0.13

Dividend Yield

IONS

N/A

UHS

0.52%

5Y Dividends CAGR

IONS

N/A

UHS

14.87%

5Y EPS CAGR

IONS

-21.44%

Winner

UHS

18.25%

Debt to Equity

IONS

88.01%

Winner

UHS

63.07%

Free Cash Flow Yield

IONS

-10.70%

Winner

UHS

10.10%

IONS vs UHS - Historical Returns

Returns include dividend reinvestment.

Period	IONS	UHS
1 month	-26.00%	+1.40%
3 months	-28.76%	-17.72%
6 months	-29.12%	-27.34%
1 year	+30.31%	-15.98%
5 years(CAGR)	+8.94%	-0.16%
10 years(CAGR)	+7.21%	+1.34%
Max(CAGR)	+6.28%	+12.30%

IONS

-26.00%

Winner

UHS

+1.40%

IONS

-28.76%

Winner

UHS

-17.72%

IONS

-29.12%

Winner

UHS

-27.34%

Winner

IONS

+30.31%

UHS

-15.98%

5Y(CAGR)

Winner

IONS

+8.94%

UHS

-0.16%

10Y(CAGR)

Winner

IONS

+7.21%

UHS

+1.34%

Max(CAGR)

IONS

+6.28%

Winner

UHS

+12.30%

IONS vs UHS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	UHS
2026	-31.30%	-32.52%
2025	+128.05%	+21.85%
2024	-33.88%	+15.19%
2023	+34.62%	+7.53%
2022	+15.86%	+7.42%
2021	-46.41%	-3.61%
2020	-7.14%	-3.22%
2019	+12.35%	+22.69%
2018	+9.77%	+1.16%
2017	+6.25%	+6.60%
2016	-22.45%	-9.49%
2015	+0.58%	+8.02%
2014	+54.85%	+38.42%
2013	+268.21%	+64.01%
2012	+44.00%	+29.95%
2011	-29.93%	-10.12%
2010	-10.20%	+40.17%
2009	-23.22%	+60.97%
2008	-7.80%	-25.13%
2007	+44.10%	-7.73%
2006	+111.81%	+18.90%
2005	-9.66%	+6.90%
2004	-13.36%	-16.42%
2003	-4.97%	+15.58%
2002	-68.69%	+6.12%
2001	+130.55%	-15.03%
2000	+77.49%	+200.13%
1999	-44.34%	+19.76%

IONS vs UHS Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for UHS was -56.30%, occurring on Mar 18, 2020. Recovery took 418 trading sessions.

The current IONS drawdown is -36.73%. The current UHS drawdown is -39.19%.

Rank	IONS	UHS
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-56.30% Sep 10, 2019 - May 7, 2021
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-52.49% Sep 12, 2008 - Oct 8, 2009
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-44.89% Aug 3, 2021 - Jan 11, 2024
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-43.31% May 10, 2011 - Jan 22, 2013
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-42.00% Nov 26, 2025 - Jun 18, 2026
#6	-36.73% Feb 6, 2026 - Jul 15, 2026	-38.13% Oct 16, 2002 - Feb 12, 2004
#7	-28.35% Jul 12, 2013 - Sep 19, 2013	-35.64% Sep 24, 2024 - Nov 25, 2025
#8	-20.89% Sep 23, 2013 - Nov 27, 2013	-34.03% Aug 4, 2015 - Jul 26, 2019
#9	-19.78% Jan 12, 2015 - Mar 19, 2015	-32.38% Dec 27, 2000 - Oct 16, 2002
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-29.08% Feb 12, 2004 - Apr 29, 2005
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-28.25% Jun 3, 2010 - Dec 17, 2010
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-28.14% Jun 14, 2005 - Jun 1, 2007
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-25.59% Jun 4, 2007 - Apr 28, 2008
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-21.01% Feb 4, 2000 - Mar 31, 2000
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-16.52% Oct 9, 2009 - Jan 14, 2010

Correlation

Correlation between IONS and UHS is 0.84 which considered as a strong positive correlation - the stocks tend to move together.

0.84

-101

Dividend Comparison (1999 - 2026)

IONS vs UHS dividend yield comparison.

Year	IONS	UHS
2026	0.00%	0.27%
2025	0.00%	0.37%
2024	0.00%	0.45%
2023	0.00%	0.52%
2022	0.00%	0.57%
2021	0.00%	0.62%
2020	0.00%	0.15%
2019	0.00%	0.42%
2018	0.00%	0.34%
2017	0.00%	0.35%
2016	0.00%	0.38%
2015	0.00%	0.33%
2014	0.00%	0.27%
2013	0.00%	0.25%
2012	0.00%	1.24%
2011	0.00%	0.51%
2010	0.00%	0.46%
2009	0.00%	0.48%
2008	0.00%	0.85%
2007	0.00%	0.63%
2006	0.00%	0.58%
2005	0.00%	0.68%
2004	0.00%	0.72%
2003	0.00%	0.15%
2000	4.85%	0.00%
1999	3.52%	0.00%