IONS vs NCLH

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Norwegian Cruise Line Holdings Ltd (NCLH, Company).

IONS is from the Healthcare sector, while NCLH is from the Consumer Cyclical sector.

5-Year PerformanceIONS has outperformed NCLH, delivering a return of +8.9% compared to -4.2%

IONS vs NCLH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	NCLH(COMPANY)
Market Cap	$9.08B	$9.06B
Max Drawdown	91.72%	87.81%
Sharpe Ratio	0.66	-0.11
5Y Beta	0.66	1.84
Industry	Biotechnology	Travel Services
P/E Ratio	-51.94	15.82
Forward P/E	90.91	11.42
PEG Ratio	-1.10	N/A
5Y EPS CAGR	-21.44%	N/A
Debt to Equity	88.01%	0.00%
Free Cash Flow Yield	-10.70%	-10.48%

Market Cap

Winner

IONS

$9.08B

NCLH

$9.06B

Max Drawdown

IONS

91.72%

Winner

NCLH

87.81%

Sharpe Ratio

Winner

IONS

0.66

NCLH

-0.11

5Y Beta

Winner

IONS

0.66

NCLH

1.84

Industry

IONS

Biotechnology

NCLH

Travel Services

P/E Ratio

Winner

IONS

-51.94

NCLH

15.82

Forward P/E

IONS

90.91

Winner

NCLH

11.42

PEG Ratio

IONS

-1.10

NCLH

N/A

5Y EPS CAGR

IONS

-21.44%

NCLH

N/A

Debt to Equity

IONS

88.01%

Winner

NCLH

0.00%

Free Cash Flow Yield

IONS

-10.70%

Winner

NCLH

-10.48%

IONS vs NCLH - Historical Returns

Returns include dividend reinvestment.

Period	IONS	NCLH
1 month	-26.00%	-2.04%
3 months	-28.76%	-6.58%
6 months	-29.12%	-13.73%
1 year	+30.31%	-13.24%
5 years(CAGR)	+8.94%	-4.20%
10 years(CAGR)	+7.21%	-7.10%
Max(CAGR)	+6.28%	-1.68%

IONS

-26.00%

Winner

NCLH

-2.04%

IONS

-28.76%

Winner

NCLH

-6.58%

IONS

-29.12%

Winner

NCLH

-13.73%

Winner

IONS

+30.31%

NCLH

-13.24%

5Y(CAGR)

Winner

IONS

+8.94%

NCLH

-4.20%

10Y(CAGR)

Winner

IONS

+7.21%

NCLH

-7.10%

Max(CAGR)

Winner

IONS

+6.28%

NCLH

-1.68%

IONS vs NCLH - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	NCLH
2026	-31.30%	-13.39%
2025	+128.05%	-13.89%
2024	-33.88%	+40.45%
2023	+34.62%	+68.97%
2022	+15.86%	-44.82%
2021	-46.41%	-12.60%
2020	-7.14%	-56.77%
2019	+12.35%	+37.82%
2018	+9.77%	-22.87%
2017	+6.25%	+24.44%
2016	-22.45%	-26.66%
2015	+0.58%	+25.48%
2014	+54.85%	+34.99%
2013	+268.21%	+43.08%
2012	+44.00%	N/A
2011	-29.93%	N/A
2010	-10.20%	N/A
2009	-23.22%	N/A
2008	-7.80%	N/A
2007	+44.10%	N/A
2006	+111.81%	N/A
2005	-9.66%	N/A
2004	-13.36%	N/A
2003	-4.97%	N/A
2002	-68.69%	N/A
2001	+130.55%	N/A
2000	+77.49%	N/A
1999	-44.34%	N/A

IONS vs NCLH Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for NCLH was -87.81%, occurring on Mar 18, 2020. This drawdown has not yet recovered.

The current IONS drawdown is -36.73%. The current NCLH drawdown is -69.06%.

Rank	IONS	NCLH
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-87.81% Nov 2, 2015 - Mar 18, 2020
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-19.67% Jan 16, 2014 - Sep 2, 2014
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-16.00% Sep 2, 2014 - Oct 30, 2014
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-12.22% Jul 31, 2015 - Oct 26, 2015
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-12.07% May 24, 2013 - Aug 13, 2013
#6	-36.73% Feb 6, 2026 - Jul 15, 2026	-11.75% Apr 9, 2015 - May 15, 2015
#7	-28.35% Jul 12, 2013 - Sep 19, 2013	-10.62% Dec 29, 2014 - Feb 19, 2015
#8	-20.89% Sep 23, 2013 - Nov 27, 2013	-10.18% Sep 19, 2013 - Nov 21, 2013
#9	-19.78% Jan 12, 2015 - Mar 19, 2015	-7.89% Nov 27, 2013 - Dec 20, 2013
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-7.34% Feb 19, 2013 - May 2, 2013
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-5.30% Jan 28, 2013 - Feb 4, 2013
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-5.18% Aug 15, 2013 - Sep 17, 2013
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-5.11% May 19, 2015 - Jul 10, 2015
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-4.73% Mar 20, 2015 - Mar 27, 2015
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-4.51% May 8, 2013 - May 20, 2013