INFA vs SYRE

Comparison between Informatica Inc. (INFA, Company) and Spyre Therapeutics Inc (SYRE, Company).

INFA is from the Technology sector, while SYRE is from the Healthcare sector.

5-Year PerformanceINFA has outperformed SYRE, delivering a return of -3.3% compared to -9.4%

INFA vs SYRE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	INFA(COMPANY)	SYRE(COMPANY)
Market Cap	$7.80B	$7.82B
Max Drawdown	63.71%	99.11%
Sharpe Ratio	0.15	2.87
5Y Beta	0.57	1.75
Industry	Software - Infrastructure	Biotechnology
P/E Ratio	755.27	-40.18
Forward P/E	19.16	N/A
5Y EPS CAGR	N/A	-2.15%
Debt to Equity	73.42%	0.00%
Free Cash Flow Yield	5.98%	-2.37%
P/S Ratio	4.64	650.22
P/B Ratio	3.18	17.32

Market Cap

INFA

$7.80B

Winner

SYRE

$7.82B

Max Drawdown

Winner

INFA

63.71%

SYRE

99.11%

Sharpe Ratio

INFA

0.15

Winner

SYRE

2.87

5Y Beta

Winner

INFA

0.57

SYRE

1.75

Industry

INFA

Software - Infrastructure

SYRE

Biotechnology

P/E Ratio

INFA

755.27

Winner

SYRE

-40.18

Forward P/E

INFA

19.16

SYRE

N/A

5Y EPS CAGR

INFA

N/A

SYRE

-2.15%

Debt to Equity

INFA

73.42%

Winner

SYRE

0.00%

Free Cash Flow Yield

Winner

INFA

5.98%

SYRE

-2.37%

P/S Ratio

Winner

INFA

4.64

SYRE

650.22

P/B Ratio

Winner

INFA

3.18

SYRE

17.32

INFA vs SYRE - Historical Returns

Returns include dividend reinvestment.

Period	INFA	SYRE
1 month	+0.00%	+3.03%
3 months	N/A	+44.41%
6 months	+0.00%	+212.13%
1 year	+1.02%	+461.43%
5 years(CAGR)	-3.26%	-9.42%
10 years(CAGR)	N/A	-1.50%
Max(CAGR)	-3.26%	-8.31%

INFA

+0.00%

Winner

SYRE

+3.03%

INFA

N/A

SYRE

+44.41%

INFA

+0.00%

Winner

SYRE

+212.13%

INFA

+1.02%

Winner

SYRE

+461.43%

5Y(CAGR)

Winner

INFA

-3.26%

SYRE

-9.42%

10Y(CAGR)

INFA

N/A

SYRE

-1.50%

Max(CAGR)

Winner

INFA

-3.26%

SYRE

-8.31%

INFA vs SYRE - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	INFA	SYRE
2026	+0.00%	+226.98%
2025	-2.63%	+37.36%
2024	-3.78%	+8.79%
2023	+83.99%	+104.27%
2022	-54.69%	-90.57%
2021	+27.52%	-44.51%
2020	N/A	+1.55%
2019	N/A	-4.98%
2018	N/A	+39.22%
2017	N/A	+18.38%
2016	N/A	-55.48%

INFA vs SYRE Drawdown Comparison

The maximum drawdown for INFA was -63.71%, occurring on May 4, 2023. This drawdown has not yet recovered.

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The current INFA drawdown is -36.16%. The current SYRE drawdown is -66.64%.

Rank	INFA	SYRE
#1	-63.71% Dec 15, 2021 - May 4, 2023	-99.11% Apr 8, 2016 - Jun 21, 2023
#2	-6.42% Nov 29, 2021 - Dec 7, 2021	N/A
#3	-5.63% Dec 10, 2021 - Dec 15, 2021	N/A
#4	-4.63% Nov 18, 2021 - Nov 29, 2021	N/A
#5	-3.82% Dec 8, 2021 - Dec 10, 2021	N/A
#6	-2.56% Nov 15, 2021 - Nov 18, 2021	N/A
#7	-1.67% Nov 9, 2021 - Nov 15, 2021	N/A
#8	-0.64% Nov 4, 2021 - Nov 8, 2021	N/A
#9	-0.03% Oct 29, 2021 - Nov 2, 2021	N/A