DNLI vs SBCF

Comparison between Denali Therapeutics Inc (DNLI, Company) and Seacoast Banking Corp Of Florida (SBCF, Company).

DNLI is from the Healthcare sector, while SBCF is from the Financial Services sector.

5-Year PerformanceSBCF has outperformed DNLI, delivering a return of -1.7% compared to -21.1%

DNLI vs SBCF - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	SBCF(COMPANY)
Market Cap	$2.99B	$2.99B
Max Drawdown	87.74%	96.46%
Sharpe Ratio	0.84	0.92
5Y Beta	1.56	1.03
Industry	Biotechnology	Banks - Regional
P/E Ratio	-5.62	19.28
Forward P/E	N/A	16.92
PEG Ratio	-0.88	2.62
Dividend Yield	N/A	2.43%
5Y EPS CAGR	N/A	-4.74%
Debt to Equity	0.00%	4.15%
Free Cash Flow Yield	-14.12%	7.65%
P/S Ratio	3643.65	4.73
P/B Ratio	3.10	1.06

Market Cap

DNLI

$2.99B

Winner

SBCF

$2.99B

Max Drawdown

Winner

DNLI

87.74%

SBCF

96.46%

Sharpe Ratio

DNLI

0.84

Winner

SBCF

0.92

5Y Beta

DNLI

1.56

Winner

SBCF

1.03

Industry

DNLI

Biotechnology

SBCF

Banks - Regional

P/E Ratio

Winner

DNLI

-5.62

SBCF

19.28

Forward P/E

DNLI

N/A

SBCF

16.92

PEG Ratio

Winner

DNLI

-0.88

SBCF

2.62

Dividend Yield

DNLI

N/A

SBCF

2.43%

5Y EPS CAGR

DNLI

N/A

SBCF

-4.74%

Debt to Equity

Winner

DNLI

0.00%

SBCF

4.15%

Free Cash Flow Yield

DNLI

-14.12%

Winner

SBCF

7.65%

P/S Ratio

DNLI

3643.65

Winner

SBCF

4.73

P/B Ratio

DNLI

3.10

Winner

SBCF

1.06

DNLI vs SBCF - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	SBCF
1 month	+1.35%	-3.98%
3 months	-4.58%	-1.79%
6 months	+4.18%	-2.81%
1 year	+52.99%	+23.50%
5 years(CAGR)	-21.07%	-1.71%
10 years(CAGR)	-0.70%	+7.39%
Max(CAGR)	-0.70%	+0.30%

Winner

DNLI

+1.35%

SBCF

-3.98%

DNLI

-4.58%

Winner

SBCF

-1.79%

Winner

DNLI

+4.18%

SBCF

-2.81%

Winner

DNLI

+52.99%

SBCF

+23.50%

5Y(CAGR)

DNLI

-21.07%

Winner

SBCF

-1.71%

10Y(CAGR)

DNLI

-0.70%

Winner

SBCF

+7.39%

Max(CAGR)

DNLI

-0.70%

Winner

SBCF

+0.30%

DNLI vs SBCF - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DNLI	SBCF
2026	+24.22%	-3.31%
2025	-20.78%	+20.89%
2024	-4.72%	+0.91%
2023	-22.33%	-7.66%
2022	-41.17%	-11.40%
2021	-37.06%	+22.77%
2020	+411.04%	-3.60%
2019	-9.88%	+16.24%
2018	+28.08%	+4.50%
2017	-27.09%	+11.99%
2016	N/A	+50.17%
2015	N/A	+9.34%
2014	N/A	+12.80%
2013	N/A	+48.78%
2012	N/A	+3.87%
2011	N/A	+0.66%
2010	N/A	-17.51%
2009	N/A	-74.70%
2008	N/A	-32.17%
2007	N/A	-56.58%
2006	N/A	+7.09%
2005	N/A	+8.31%
2004	N/A	+28.59%
2003	N/A	+5.28%
2002	N/A	+30.08%
2001	N/A	+77.78%
2000	N/A	-3.38%
1999	N/A	+3.13%

DNLI vs SBCF Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for SBCF was -96.16%, occurring on Aug 26, 2010. This drawdown has not yet recovered.

The current DNLI drawdown is -78.40%. The current SBCF drawdown is -76.49%.

Rank	DNLI	SBCF
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-96.16% Sep 28, 2006 - Aug 26, 2010
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-23.61% Nov 12, 2004 - Jul 22, 2005
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-22.93% Sep 11, 2002 - Feb 6, 2004
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-17.82% Nov 26, 1999 - Jan 9, 2001
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-16.96% Jun 28, 2002 - Sep 9, 2002
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-15.09% Aug 2, 2005 - Jan 26, 2006
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-14.65% Apr 19, 2006 - Jul 27, 2006
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-14.55% Oct 4, 2001 - Nov 27, 2001
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-13.30% Apr 5, 2004 - Aug 3, 2004
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-11.87% Aug 16, 2001 - Oct 3, 2001
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-9.93% Feb 6, 2001 - May 7, 2001
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-9.61% Aug 30, 2006 - Sep 27, 2006
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-9.01% Sep 15, 2004 - Nov 3, 2004
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-8.64% May 2, 2002 - Jun 20, 2002
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-6.38% Aug 4, 2006 - Aug 30, 2006