DNLI vs RCUS

Comparison between Denali Therapeutics Inc (DNLI, Company) and Arcus Biosciences Inc (RCUS, Company).

Both DNLI and RCUS are from the Healthcare sector.

5-Year PerformanceRCUS has outperformed DNLI, delivering a return of -0.8% compared to -21.1%

DNLI vs RCUS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	RCUS(COMPANY)
Market Cap	$2.99B	$2.98B
Max Drawdown	87.74%	85.83%
Sharpe Ratio	0.84	1.88
5Y Beta	1.56	1.50
Industry	Biotechnology	Biotechnology
P/E Ratio	-5.62	-5.67
PEG Ratio	-0.88	-0.16
5Y EPS CAGR	N/A	14.36%
Debt to Equity	0.00%	19.08%
Free Cash Flow Yield	-14.12%	-16.41%
P/S Ratio	3643.65	12.65
P/B Ratio	3.10	5.46

Market Cap

Winner

DNLI

$2.99B

RCUS

$2.98B

Max Drawdown

DNLI

87.74%

Winner

RCUS

85.83%

Sharpe Ratio

DNLI

0.84

Winner

RCUS

1.88

5Y Beta

DNLI

1.56

Winner

RCUS

1.50

Industry

DNLI

Biotechnology

RCUS

Biotechnology

P/E Ratio

DNLI

-5.62

Winner

RCUS

-5.67

PEG Ratio

Winner

DNLI

-0.88

RCUS

-0.16

5Y EPS CAGR

DNLI

N/A

RCUS

14.36%

Debt to Equity

Winner

DNLI

0.00%

RCUS

19.08%

Free Cash Flow Yield

Winner

DNLI

-14.12%

RCUS

-16.41%

P/S Ratio

DNLI

3643.65

Winner

RCUS

12.65

P/B Ratio

Winner

DNLI

3.10

RCUS

5.46

DNLI vs RCUS - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	RCUS
1 month	+1.35%	-3.93%
3 months	-4.58%	+17.67%
6 months	+4.18%	-6.22%
1 year	+52.99%	+165.45%
5 years(CAGR)	-21.07%	-0.75%
10 years(CAGR)	-0.70%	+4.28%
Max(CAGR)	-0.70%	+4.28%

Winner

DNLI

+1.35%

RCUS

-3.93%

DNLI

-4.58%

Winner

RCUS

+17.67%

Winner

DNLI

+4.18%

RCUS

-6.22%

DNLI

+52.99%

Winner

RCUS

+165.45%

5Y(CAGR)

DNLI

-21.07%

Winner

RCUS

-0.75%

10Y(CAGR)

DNLI

-0.70%

Winner

RCUS

+4.28%

Max(CAGR)

DNLI

-0.70%

Winner

RCUS

+4.28%

DNLI vs RCUS - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	DNLI	RCUS
2026	+24.22%	+2.92%
2025	-20.78%	+57.50%
2024	-4.72%	-24.34%
2023	-22.33%	-5.45%
2022	-41.17%	-50.56%
2021	-37.06%	+54.70%
2020	+411.04%	+163.29%
2019	-9.88%	-5.43%
2018	+28.08%	-36.65%
2017	-27.09%	N/A

DNLI vs RCUS Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for RCUS was -85.83%, occurring on Apr 4, 2025. This drawdown has not yet recovered.

The current DNLI drawdown is -78.40%. The current RCUS drawdown is -50.55%.

Rank	DNLI	RCUS
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-85.83% Nov 23, 2021 - Apr 4, 2025
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-63.64% Mar 21, 2018 - Mar 4, 2020
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-53.50% May 20, 2020 - Jan 14, 2021
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-48.13% Mar 6, 2020 - Apr 16, 2020
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-45.04% Feb 8, 2021 - Nov 18, 2021
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-12.83% Apr 20, 2020 - May 11, 2020
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-10.95% Jan 14, 2021 - Feb 3, 2021
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-4.94% Mar 16, 2018 - Mar 21, 2018
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-4.71% Apr 16, 2020 - Apr 20, 2020
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-4.05% May 15, 2020 - May 20, 2020
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-3.81% May 11, 2020 - May 13, 2020
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	N/A
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	N/A
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	N/A
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	N/A