DNLI vs RCUS

Comparison between Denali Therapeutics Inc (DNLI, Company) and Arcus Biosciences Inc (RCUS, Company).

Both DNLI and RCUS are from the Healthcare sector.

5-Year PerformanceRCUS has outperformed DNLI, delivering a return of -2.0% compared to -18.2%

DNLI vs RCUS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	RCUS(COMPANY)
Market Cap	$3.75B	$3.76B
Max Drawdown	87.74%	85.83%
Sharpe Ratio	1.13	2.16
5Y Beta	1.47	1.51
Industry	Biotechnology	Biotechnology
P/E Ratio	-7.06	-7.16
PEG Ratio	-1.10	-0.20
5Y EPS CAGR	N/A	14.36%
Debt to Equity	0.00%	19.08%
Free Cash Flow Yield	-11.25%	-13.00%
P/S Ratio	3643.65	15.97
P/B Ratio	4.05	7.08

Market Cap

DNLI

$3.75B

Winner

RCUS

$3.76B

Max Drawdown

DNLI

87.74%

Winner

RCUS

85.83%

Sharpe Ratio

DNLI

1.13

Winner

RCUS

2.16

5Y Beta

Winner

DNLI

1.47

RCUS

1.51

Industry

DNLI

Biotechnology

RCUS

Biotechnology

P/E Ratio

DNLI

-7.06

Winner

RCUS

-7.16

PEG Ratio

Winner

DNLI

-1.10

RCUS

-0.20

5Y EPS CAGR

DNLI

N/A

RCUS

14.36%

Debt to Equity

Winner

DNLI

0.00%

RCUS

19.08%

Free Cash Flow Yield

Winner

DNLI

-11.25%

RCUS

-13.00%

P/S Ratio

DNLI

3643.65

Winner

RCUS

15.97

P/B Ratio

Winner

DNLI

4.05

RCUS

7.08

DNLI vs RCUS - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	RCUS
1 month	-5.45%	+5.50%
3 months	+20.41%	+18.30%
6 months	+15.65%	+34.34%
1 year	+61.85%	+204.92%
5 years(CAGR)	-18.19%	-1.98%
10 years(CAGR)	+1.02%	+6.92%
Max(CAGR)	+1.02%	+6.92%

DNLI

-5.45%

Winner

RCUS

+5.50%

Winner

DNLI

+20.41%

RCUS

+18.30%

DNLI

+15.65%

Winner

RCUS

+34.34%

DNLI

+61.85%

Winner

RCUS

+204.92%

5Y(CAGR)

DNLI

-18.19%

Winner

RCUS

-1.98%

10Y(CAGR)

DNLI

+1.02%

Winner

RCUS

+6.92%

Max(CAGR)

DNLI

+1.02%

Winner

RCUS

+6.92%

DNLI vs RCUS - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	DNLI	RCUS
2026	+43.95%	+27.65%
2025	-20.78%	+57.50%
2024	-4.72%	-24.34%
2023	-22.33%	-5.45%
2022	-41.17%	-50.56%
2021	-37.06%	+54.70%
2020	+411.04%	+163.29%
2019	-9.88%	-5.43%
2018	+28.08%	-36.65%
2017	-27.09%	N/A

DNLI vs RCUS Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for RCUS was -85.83%, occurring on Apr 4, 2025. This drawdown has not yet recovered.

The current DNLI drawdown is -74.97%. The current RCUS drawdown is -38.66%.

Rank	DNLI	RCUS
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-85.83% Nov 23, 2021 - Apr 4, 2025
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-63.64% Mar 21, 2018 - Mar 4, 2020
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-53.50% May 20, 2020 - Jan 14, 2021
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-48.13% Mar 6, 2020 - Apr 16, 2020
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-45.04% Feb 8, 2021 - Nov 18, 2021
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-12.83% Apr 20, 2020 - May 11, 2020
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-10.95% Jan 14, 2021 - Feb 3, 2021
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-4.94% Mar 16, 2018 - Mar 21, 2018
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-4.71% Apr 16, 2020 - Apr 20, 2020
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-4.05% May 15, 2020 - May 20, 2020
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-3.81% May 11, 2020 - May 13, 2020
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	N/A
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	N/A
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	N/A
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	N/A