DNLI vs FIBK

Comparison between Denali Therapeutics Inc (DNLI, Company) and First Interstate BancSystem Inc (FIBK, Company).

DNLI is from the Healthcare sector, while FIBK is from the Financial Services sector.

5-Year PerformanceFIBK has outperformed DNLI, delivering a return of +3.9% compared to -18.2%

DNLI vs FIBK - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	FIBK(COMPANY)
Market Cap	$3.75B	$3.74B
Max Drawdown	87.74%	57.34%
Sharpe Ratio	1.13	1.00
5Y Beta	1.47	1.10
Industry	Biotechnology	Banks - Regional
P/E Ratio	-7.06	12.53
Forward P/E	N/A	13.00
PEG Ratio	-1.10	0.27
Dividend Yield	N/A	4.82%
5Y Dividends CAGR	N/A	8.82%
5Y EPS CAGR	N/A	3.20%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-11.25%	7.54%
P/S Ratio	3643.65	3.59
P/B Ratio	4.05	1.13

Market Cap

Winner

DNLI

$3.75B

FIBK

$3.74B

Max Drawdown

DNLI

87.74%

Winner

FIBK

57.34%

Sharpe Ratio

Winner

DNLI

1.13

FIBK

1.00

5Y Beta

DNLI

1.47

Winner

FIBK

1.10

Industry

DNLI

Biotechnology

FIBK

Banks - Regional

P/E Ratio

Winner

DNLI

-7.06

FIBK

12.53

Forward P/E

DNLI

N/A

FIBK

13.00

PEG Ratio

Winner

DNLI

-1.10

FIBK

0.27

Dividend Yield

DNLI

N/A

FIBK

4.82%

5Y Dividends CAGR

DNLI

N/A

FIBK

8.82%

5Y EPS CAGR

DNLI

N/A

FIBK

3.20%

Debt to Equity

DNLI

0.00%

FIBK

0.00%

Free Cash Flow Yield

DNLI

-11.25%

Winner

FIBK

7.54%

P/S Ratio

DNLI

3643.65

Winner

FIBK

3.59

P/B Ratio

DNLI

4.05

Winner

FIBK

1.13

DNLI vs FIBK - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	FIBK
1 month	-5.45%	+2.06%
3 months	+20.41%	+10.76%
6 months	+15.65%	+6.62%
1 year	+61.85%	+32.28%
5 years(CAGR)	-18.19%	+3.92%
10 years(CAGR)	+1.02%	+7.77%
Max(CAGR)	+1.02%	+9.82%

DNLI

-5.45%

Winner

FIBK

+2.06%

Winner

DNLI

+20.41%

FIBK

+10.76%

Winner

DNLI

+15.65%

FIBK

+6.62%

Winner

DNLI

+61.85%

FIBK

+32.28%

5Y(CAGR)

DNLI

-18.19%

Winner

FIBK

+3.92%

10Y(CAGR)

DNLI

+1.02%

Winner

FIBK

+7.77%

Max(CAGR)

DNLI

+1.02%

Winner

FIBK

+9.82%

DNLI vs FIBK - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	DNLI	FIBK
2026	+43.95%	+10.73%
2025	-20.78%	+15.15%
2024	-4.72%	+11.17%
2023	-22.33%	-15.51%
2022	-41.17%	-2.70%
2021	-37.06%	+4.65%
2020	+411.04%	+3.65%
2019	-9.88%	+16.58%
2018	+28.08%	-6.61%
2017	-27.09%	-3.95%
2016	N/A	+56.37%
2015	N/A	+9.83%
2014	N/A	+1.89%
2013	N/A	+83.40%
2012	N/A	+18.94%
2011	N/A	-13.31%
2010	N/A	-0.01%

DNLI vs FIBK Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for FIBK was -52.51%, occurring on May 12, 2023. Recovery took 1233 trading sessions.

The current DNLI drawdown is -74.97%. The current FIBK drawdown is -5.27%.

Rank	DNLI	FIBK
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-52.51% Mar 12, 2021 - Feb 9, 2026
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-41.42% Sep 5, 2018 - Jan 6, 2021
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-37.73% Apr 23, 2010 - Sep 24, 2012
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-23.91% Mar 1, 2017 - May 21, 2018
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-18.41% Nov 12, 2014 - Nov 2, 2015
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-18.28% Dec 4, 2015 - Aug 18, 2016
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-16.86% Feb 9, 2026 - Jun 25, 2026
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-15.74% Dec 24, 2013 - Oct 29, 2014
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-13.55% Oct 5, 2012 - Jan 2, 2013
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-11.31% Jan 12, 2021 - Feb 10, 2021
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-7.89% Jan 4, 2017 - Feb 23, 2017
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-6.95% Mar 15, 2013 - Apr 29, 2013
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-6.47% Aug 2, 2013 - Sep 10, 2013
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-6.29% Sep 18, 2013 - Oct 21, 2013
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-6.12% Nov 17, 2016 - Dec 2, 2016