CYTK vs KRYS

Comparison between Cytokinetics Inc (CYTK, Company) and Krystal Biotech Inc (KRYS, Company).

Both CYTK and KRYS are from the Healthcare sector.

5-Year PerformanceKRYS has outperformed CYTK, delivering a return of +40.4% compared to +19.2%

CYTK vs KRYS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CYTK(COMPANY)	KRYS(COMPANY)
Market Cap	$9.72B	$9.64B
Max Drawdown	97.09%	53.42%
Sharpe Ratio	1.50	2.34
5Y Beta	0.73	0.87
Industry	Biotechnology	Biotechnology
P/E Ratio	-11.52	39.49
Forward P/E	117.65	42.37
PEG Ratio	-0.40	0.64
5Y EPS CAGR	27.73%	N/A
Debt to Equity	-155.91%	0.00%
Free Cash Flow Yield	-5.65%	2.67%
P/S Ratio	101.17	21.89
P/B Ratio	60.31	7.88

Market Cap

Winner

CYTK

$9.72B

KRYS

$9.64B

Max Drawdown

CYTK

97.09%

Winner

KRYS

53.42%

Sharpe Ratio

CYTK

1.50

Winner

KRYS

2.34

5Y Beta

Winner

CYTK

0.73

KRYS

0.87

Industry

CYTK

Biotechnology

KRYS

Biotechnology

P/E Ratio

Winner

CYTK

-11.52

KRYS

39.49

Forward P/E

CYTK

117.65

Winner

KRYS

42.37

PEG Ratio

Winner

CYTK

-0.40

KRYS

0.64

5Y EPS CAGR

CYTK

27.73%

KRYS

N/A

Debt to Equity

Winner

CYTK

-155.91%

KRYS

0.00%

Free Cash Flow Yield

CYTK

-5.65%

Winner

KRYS

2.67%

P/S Ratio

CYTK

101.17

Winner

KRYS

21.89

P/B Ratio

CYTK

60.31

Winner

KRYS

7.88

CYTK vs KRYS - Historical Returns

Returns include dividend reinvestment.

Period	CYTK	KRYS
1 month	-10.29%	-11.44%
3 months	+3.32%	+10.03%
6 months	+23.13%	+19.69%
1 year	+117.76%	+139.86%
5 years(CAGR)	+19.25%	+40.35%
10 years(CAGR)	+20.40%	+47.05%
Max(CAGR)	-1.03%	+47.05%

Winner

CYTK

-10.29%

KRYS

-11.44%

CYTK

+3.32%

Winner

KRYS

+10.03%

Winner

CYTK

+23.13%

KRYS

+19.69%

CYTK

+117.76%

Winner

KRYS

+139.86%

5Y(CAGR)

CYTK

+19.25%

Winner

KRYS

+40.35%

10Y(CAGR)

CYTK

+20.40%

Winner

KRYS

+47.05%

Max(CAGR)

CYTK

-1.03%

Winner

KRYS

+47.05%

CYTK vs KRYS - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	CYTK	KRYS
2026	+24.35%	+32.21%
2025	+29.86%	+57.53%
2024	-44.08%	+25.37%
2023	+88.25%	+56.58%
2022	-0.39%	+9.86%
2021	+133.03%	+17.72%
2020	+96.97%	+5.28%
2019	+55.57%	+142.47%
2018	-27.77%	+126.36%
2017	-34.27%	-1.13%
2016	+21.50%	N/A
2015	+41.93%	N/A
2014	+19.20%	N/A
2013	+61.64%	N/A
2012	-32.65%	N/A
2011	-55.56%	N/A
2010	-32.80%	N/A
2009	+2.11%	N/A
2008	-37.36%	N/A
2007	-43.29%	N/A
2006	+19.30%	N/A
2005	-33.33%	N/A
2004	-36.34%	N/A

CYTK vs KRYS Drawdown Comparison

The maximum drawdown for CYTK was -97.09%, occurring on Oct 10, 2014. Recovery took 4952 trading sessions.

The maximum drawdown for KRYS was -53.42%, occurring on Nov 26, 2021. Recovery took 190 trading sessions.

The current CYTK drawdown is -28.97%. The current KRYS drawdown is -13.67%.

Rank	CYTK	KRYS
#1	-97.09% May 5, 2004 - Jan 8, 2024	-53.42% Mar 1, 2021 - Nov 29, 2021
#2	-72.39% Jan 8, 2024 - May 15, 2025	-46.65% Feb 12, 2020 - Jan 8, 2021
#3	-1.52% May 3, 2004 - May 5, 2004	-44.55% Nov 29, 2021 - Apr 13, 2023
#4	N/A	-42.26% Jul 26, 2024 - Nov 24, 2025
#5	N/A	-35.34% Jul 22, 2019 - Nov 13, 2019
#6	N/A	-28.43% Sep 11, 2018 - Oct 16, 2018
#7	N/A	-27.86% Dec 13, 2019 - Feb 12, 2020
#8	N/A	-26.81% Oct 18, 2017 - Mar 16, 2018
#9	N/A	-26.58% Jan 8, 2019 - Mar 25, 2019
#10	N/A	-26.34% Jun 13, 2023 - Jan 22, 2024
#11	N/A	-24.99% May 14, 2019 - Jun 24, 2019
#12	N/A	-24.14% Oct 16, 2018 - Nov 30, 2018
#13	N/A	-23.42% Mar 16, 2018 - Jun 6, 2018
#14	N/A	-19.86% Nov 30, 2018 - Jan 7, 2019
#15	N/A	-17.56% Jan 22, 2024 - Feb 26, 2024