CYTK vs RYAN

Comparison between Cytokinetics Inc (CYTK, Company) and Ryan Specialty Holdings Inc Class A (RYAN, Company).

CYTK is from the Healthcare sector, while RYAN is from the Financial Services sector.

5-Year PerformanceCYTK has outperformed RYAN, delivering a return of +27.9% compared to +4.0%

CYTK vs RYAN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CYTK(COMPANY)	RYAN(COMPANY)
Market Cap	$9.71B	$9.72B
Max Drawdown	97.09%	61.29%
Sharpe Ratio	1.73	-1.79
5Y Beta	0.78	0.35
Industry	Biotechnology	Insurance - Specialty
P/E Ratio	-11.51	310.05
Forward P/E	117.65	16.03
PEG Ratio	-0.40	N/A
Dividend Yield	N/A	1.47%
5Y EPS CAGR	27.73%	-29.84%
Debt to Equity	-126.00%	544.80%
Free Cash Flow Yield	-5.65%	5.92%
P/S Ratio	101.07	2.97
P/B Ratio	60.31	6.65

Market Cap

CYTK

$9.71B

Winner

RYAN

$9.72B

Max Drawdown

CYTK

97.09%

Winner

RYAN

61.29%

Sharpe Ratio

Winner

CYTK

1.73

RYAN

-1.79

5Y Beta

CYTK

0.78

Winner

RYAN

0.35

Industry

CYTK

Biotechnology

RYAN

Insurance - Specialty

P/E Ratio

Winner

CYTK

-11.51

RYAN

310.05

Forward P/E

CYTK

117.65

Winner

RYAN

16.03

PEG Ratio

CYTK

-0.40

RYAN

N/A

Dividend Yield

CYTK

N/A

RYAN

1.47%

5Y EPS CAGR

Winner

CYTK

27.73%

RYAN

-29.84%

Debt to Equity

Winner

CYTK

-126.00%

RYAN

544.80%

Free Cash Flow Yield

CYTK

-5.65%

Winner

RYAN

5.92%

P/S Ratio

CYTK

101.07

Winner

RYAN

2.97

P/B Ratio

CYTK

60.31

Winner

RYAN

6.65

CYTK vs RYAN - Historical Returns

Returns include dividend reinvestment.

Period	CYTK	RYAN
1 month	+23.85%	-6.50%
3 months	+21.81%	-17.22%
6 months	+11.94%	-43.89%
1 year	+149.89%	-53.41%
5 years(CAGR)	+27.94%	+3.98%
10 years(CAGR)	+25.18%	N/A
Max(CAGR)	-1.06%	+3.98%

Winner

CYTK

+23.85%

RYAN

-6.50%

Winner

CYTK

+21.81%

RYAN

-17.22%

Winner

CYTK

+11.94%

RYAN

-43.89%

Winner

CYTK

+149.89%

RYAN

-53.41%

5Y(CAGR)

Winner

CYTK

+27.94%

RYAN

+3.98%

10Y(CAGR)

CYTK

+25.18%

RYAN

N/A

Max(CAGR)

CYTK

-1.06%

Winner

RYAN

+3.98%

CYTK vs RYAN - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	CYTK	RYAN
2026	+23.59%	-35.60%
2025	+29.86%	-16.94%
2024	-44.08%	+51.51%
2023	+88.25%	+3.02%
2022	-0.39%	+4.96%
2021	+133.03%	+46.73%
2020	+96.97%	N/A
2019	+55.57%	N/A
2018	-27.77%	N/A
2017	-34.27%	N/A
2016	+21.50%	N/A
2015	+41.93%	N/A
2014	+19.20%	N/A
2013	+61.64%	N/A
2012	-32.65%	N/A
2011	-55.56%	N/A
2010	-32.80%	N/A
2009	+2.11%	N/A
2008	-37.36%	N/A
2007	-43.29%	N/A
2006	+19.30%	N/A
2005	-33.33%	N/A
2004	-36.34%	N/A

CYTK vs RYAN Drawdown Comparison

The maximum drawdown for CYTK was -97.09%, occurring on Oct 10, 2014. Recovery took 4952 trading sessions.

The maximum drawdown for RYAN was -60.94%, occurring on May 6, 2026. This drawdown has not yet recovered.

The current CYTK drawdown is -29.40%. The current RYAN drawdown is -56.82%.

Rank	CYTK	RYAN
#1	-97.09% May 5, 2004 - Jan 8, 2024	-60.94% Apr 3, 2025 - May 6, 2026
#2	-72.39% Jan 8, 2024 - May 15, 2025	-30.16% Aug 15, 2022 - Aug 25, 2023
#3	-1.52% May 3, 2004 - May 5, 2004	-19.44% Nov 29, 2024 - Apr 3, 2025
#4	N/A	-17.72% Apr 20, 2022 - Jul 20, 2022
#5	N/A	-16.24% Mar 2, 2022 - Apr 20, 2022
#6	N/A	-15.25% Sep 11, 2023 - Feb 28, 2024
#7	N/A	-14.25% Nov 12, 2021 - Mar 2, 2022
#8	N/A	-12.59% Mar 20, 2024 - Jun 3, 2024
#9	N/A	-10.54% Sep 7, 2021 - Oct 8, 2021
#10	N/A	-9.12% Oct 14, 2024 - Nov 22, 2024
#11	N/A	-8.49% Aug 2, 2024 - Oct 2, 2024
#12	N/A	-7.61% Jun 3, 2024 - Jun 21, 2024
#13	N/A	-7.45% Jun 24, 2024 - Jul 30, 2024
#14	N/A	-4.39% Aug 24, 2021 - Aug 31, 2021
#15	N/A	-3.60% Aug 2, 2021 - Aug 9, 2021