CRNX vs AGNCM

Comparison between Crinetics Pharmaceuticals Inc (CRNX, Company) and AGNC Investment Corp (AGNCM, Company).

CRNX is from the Healthcare sector, while AGNCM is from the Real Estate sector.

5-Year PerformanceCRNX has outperformed AGNCM, delivering a return of +36.7% compared to +7.6%

CRNX vs AGNCM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CRNX(COMPANY)	AGNCM(COMPANY)
Market Cap	$8.89B	$8.87B
Max Drawdown	68.70%	56.16%
Sharpe Ratio	1.32	0.93
5Y Beta	0.98	0.12
Industry	Biotechnology	Reit - Mortgage
P/E Ratio	-16.74	30.46
PEG Ratio	-0.73	N/A
Dividend Yield	N/A	5.73%
5Y Dividends CAGR	N/A	9.54%
5Y EPS CAGR	14.06%	N/A
Debt to Equity	0.00%	N/A
Free Cash Flow Yield	-4.78%	N/A
P/S Ratio	211.41	4.94
P/B Ratio	6.90	2.30

Market Cap

Winner

CRNX

$8.89B

AGNCM

$8.87B

Max Drawdown

CRNX

68.70%

Winner

AGNCM

56.16%

Sharpe Ratio

Winner

CRNX

1.32

AGNCM

0.93

5Y Beta

CRNX

0.98

Winner

AGNCM

0.12

Industry

CRNX

Biotechnology

AGNCM

Reit - Mortgage

P/E Ratio

Winner

CRNX

-16.74

AGNCM

30.46

PEG Ratio

CRNX

-0.73

AGNCM

N/A

Dividend Yield

CRNX

N/A

AGNCM

5.73%

5Y Dividends CAGR

CRNX

N/A

AGNCM

9.54%

5Y EPS CAGR

CRNX

14.06%

AGNCM

N/A

Debt to Equity

CRNX

0.00%

AGNCM

N/A

Free Cash Flow Yield

CRNX

-4.78%

AGNCM

N/A

P/S Ratio

CRNX

211.41

Winner

AGNCM

4.94

P/B Ratio

CRNX

6.90

Winner

AGNCM

2.30

CRNX vs AGNCM - Historical Returns

Returns include dividend reinvestment.

Period	CRNX	AGNCM
1 month	+0.66%	+1.08%
3 months	+93.33%	+2.89%
6 months	+85.69%	+5.05%
1 year	+201.58%	+9.17%
5 years(CAGR)	+36.70%	+7.57%
10 years(CAGR)	+16.54%	N/A
Max(CAGR)	+16.54%	+8.31%

CRNX

+0.66%

Winner

AGNCM

+1.08%

Winner

CRNX

+93.33%

AGNCM

+2.89%

Winner

CRNX

+85.69%

AGNCM

+5.05%

Winner

CRNX

+201.58%

AGNCM

+9.17%

5Y(CAGR)

Winner

CRNX

+36.70%

AGNCM

+7.57%

10Y(CAGR)

CRNX

+16.54%

AGNCM

N/A

Max(CAGR)

Winner

CRNX

+16.54%

AGNCM

+8.31%

CRNX vs AGNCM - Annual Returns (2018 - 2026)

Returns include dividend reinvestment.

Year	CRNX	AGNCM
2026	+79.93%	+6.24%
2025	-9.70%	+6.51%
2024	+44.48%	+16.94%
2023	+96.57%	+25.53%
2022	-35.36%	-16.89%
2021	+103.66%	+12.21%
2020	-44.45%	+3.83%
2019	-14.40%	+9.96%
2018	+22.36%	N/A

CRNX vs AGNCM Drawdown Comparison

The maximum drawdown for CRNX was -68.70%, occurring on Mar 16, 2020. Recovery took 1326 trading sessions.

The maximum drawdown for AGNCM was -55.99%, occurring on Mar 18, 2020. Recovery took 226 trading sessions.

Rank	CRNX	AGNCM
#1	-68.70% Sep 12, 2018 - Dec 19, 2023	-55.99% Feb 3, 2020 - Dec 23, 2020
#2	-57.88% Nov 8, 2024 - Jul 7, 2026	-28.38% Jan 3, 2022 - Jul 28, 2023
#3	-18.72% May 16, 2024 - Jul 11, 2024	-13.96% Sep 29, 2023 - Dec 26, 2023
#4	-17.60% Mar 1, 2024 - Mar 28, 2024	-6.49% Apr 1, 2025 - Jun 20, 2025
#5	-13.35% Jul 16, 2024 - Oct 15, 2024	-3.93% Jul 12, 2021 - Dec 31, 2021
#6	-12.30% Apr 11, 2024 - May 8, 2024	-3.65% Feb 18, 2026 - Apr 15, 2026
#7	-9.31% Aug 23, 2018 - Sep 6, 2018	-3.32% May 7, 2021 - Jun 9, 2021
#8	-8.79% Feb 9, 2024 - Feb 27, 2024	-3.04% Dec 30, 2020 - Mar 5, 2021
#9	-7.55% Jul 18, 2018 - Jul 23, 2018	-2.45% Aug 29, 2019 - Dec 18, 2019
#10	-6.96% Dec 19, 2023 - Jan 9, 2024	-2.36% Oct 7, 2025 - Dec 17, 2025
#11	-6.46% Oct 22, 2024 - Nov 7, 2024	-2.03% Aug 2, 2023 - Aug 24, 2023
#12	-6.38% Jan 9, 2024 - Feb 8, 2024	-1.97% Jun 24, 2025 - Jul 15, 2025
#13	-5.82% May 8, 2024 - May 16, 2024	-1.88% Dec 31, 2024 - Apr 1, 2025
#14	-4.49% Aug 13, 2018 - Aug 17, 2018	-1.82% Apr 21, 2021 - May 4, 2021
#15	-4.26% Feb 28, 2024 - Mar 1, 2024	-1.63% Dec 28, 2023 - Jan 8, 2024