CRDL vs AGEN

Comparison between Cardiol Therapeutics Inc - Class A (CRDL, Company) and Agenus Inc (AGEN, Company).

Both CRDL and AGEN are from the Healthcare sector.

5-Year PerformanceCRDL has outperformed AGEN, delivering a return of -14.7% compared to -50.7%

CRDL vs AGEN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CRDL(COMPANY)	AGEN(COMPANY)
Market Cap	$116M	$116M
Max Drawdown	92.71%	99.98%
Sharpe Ratio	-0.08	-0.16
5Y Beta	1.31	1.42
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	-3.75	1.80
Forward P/E	N/A	1.32
5Y EPS CAGR	-10.43%	N/A
Debt to Equity	0.48%	-27.30%
Free Cash Flow Yield	-15.22%	-75.74%

Market Cap

CRDL

$116M

Winner

AGEN

$116M

Max Drawdown

Winner

CRDL

92.71%

AGEN

99.98%

Sharpe Ratio

Winner

CRDL

-0.08

AGEN

-0.16

5Y Beta

Winner

CRDL

1.31

AGEN

1.42

Industry

CRDL

Drug Manufacturers - Specialty & Generic

AGEN

Biotechnology

P/E Ratio

Winner

CRDL

-3.75

AGEN

1.80

Forward P/E

CRDL

N/A

AGEN

1.32

5Y EPS CAGR

CRDL

-10.43%

AGEN

N/A

Debt to Equity

CRDL

0.48%

Winner

AGEN

-27.30%

Free Cash Flow Yield

Winner

CRDL

-15.22%

AGEN

-75.74%

CRDL vs AGEN - Historical Returns

Returns include dividend reinvestment.

Period	CRDL	AGEN
1 month	-17.19%	-5.06%
3 months	+7.41%	-20.21%
6 months	+4.95%	-14.53%
1 year	-19.70%	-32.89%
5 years(CAGR)	-14.72%	-50.73%
10 years(CAGR)	N/A	-27.90%
Max(CAGR)	-15.63%	-24.78%

CRDL

-17.19%

Winner

AGEN

-5.06%

Winner

CRDL

+7.41%

AGEN

-20.21%

Winner

CRDL

+4.95%

AGEN

-14.53%

Winner

CRDL

-19.70%

AGEN

-32.89%

5Y(CAGR)

Winner

CRDL

-14.72%

AGEN

-50.73%

10Y(CAGR)

CRDL

N/A

AGEN

-27.90%

Max(CAGR)

Winner

CRDL

-15.63%

AGEN

-24.78%

CRDL vs AGEN - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	CRDL	AGEN
2026	+6.62%	-7.12%
2025	-30.38%	+1.62%
2024	+45.45%	-82.88%
2023	+56.12%	-64.85%
2022	-72.58%	-30.84%
2021	-13.65%	-0.31%
2020	-39.59%	-21.29%
2019	-5.49%	+62.15%
2018	N/A	-32.77%
2017	N/A	-21.63%
2016	N/A	-7.62%
2015	N/A	+14.07%
2014	N/A	+42.81%
2013	N/A	-37.74%
2012	N/A	+88.94%
2011	N/A	-68.55%
2010	N/A	+57.17%
2009	N/A	+33.33%
2008	N/A	-76.92%
2007	N/A	+6.25%
2006	N/A	-61.80%
2005	N/A	-52.40%
2004	N/A	-11.69%
2003	N/A	+5.98%
2002	N/A	-33.89%
2001	N/A	+48.28%
2000	N/A	-76.09%

CRDL vs AGEN Drawdown Comparison

The maximum drawdown for CRDL was -92.71%, occurring on Apr 5, 2023. This drawdown has not yet recovered.

The maximum drawdown for AGEN was -99.98%, occurring on Mar 31, 2025. This drawdown has not yet recovered.

The current CRDL drawdown is -82.88%. The current AGEN drawdown is -99.95%.

Rank	CRDL	AGEN
#1	-92.71% Feb 22, 2019 - Apr 5, 2023	-99.98% Mar 9, 2000 - Mar 31, 2025
#2	-9.26% Feb 4, 2019 - Feb 19, 2019	-23.90% Feb 16, 2000 - Mar 9, 2000
#3	-1.86% Jan 18, 2019 - Jan 29, 2019	-6.50% Feb 10, 2000 - Feb 15, 2000
#4	-0.20% Jan 16, 2019 - Jan 18, 2019	-4.86% Feb 8, 2000 - Feb 10, 2000