AGEN vs COYA

Comparison between Agenus Inc (AGEN, Company) and Coya Therapeutics Inc (COYA, Company).

Both AGEN and COYA are from the Healthcare sector.

AGEN vs COYA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AGEN(COMPANY)	COYA(COMPANY)
Market Cap	$116M	$115M
Max Drawdown	99.98%	62.90%
Sharpe Ratio	-0.16	0.14
5Y Beta	1.42	1.08
Industry	Biotechnology	Biotechnology
P/E Ratio	1.80	-4.60
Forward P/E	1.32	N/A
PEG Ratio	N/A	-9.50
Debt to Equity	-27.30%	0.00%
Free Cash Flow Yield	-75.74%	-12.23%

Market Cap

Winner

AGEN

$116M

COYA

$115M

Max Drawdown

AGEN

99.98%

Winner

COYA

62.90%

Sharpe Ratio

AGEN

-0.16

Winner

COYA

0.14

5Y Beta

AGEN

1.42

Winner

COYA

1.08

Industry

AGEN

Biotechnology

COYA

Biotechnology

P/E Ratio

AGEN

1.80

Winner

COYA

-4.60

Forward P/E

AGEN

1.32

COYA

N/A

PEG Ratio

AGEN

N/A

COYA

-9.50

Debt to Equity

Winner

AGEN

-27.30%

COYA

0.00%

Free Cash Flow Yield

AGEN

-75.74%

Winner

COYA

-12.23%

AGEN vs COYA - Historical Returns

Returns include dividend reinvestment.

Period	AGEN	COYA
1 month	-5.06%	+0.00%
3 months	-20.21%	+10.56%
6 months	-14.53%	-7.17%
1 year	-32.89%	-10.71%
5 years(CAGR)	-50.73%	N/A
10 years(CAGR)	-27.90%	N/A
Max(CAGR)	-24.78%	+2.15%

AGEN

-5.06%

Winner

COYA

+0.00%

AGEN

-20.21%

Winner

COYA

+10.56%

AGEN

-14.53%

Winner

COYA

-7.17%

AGEN

-32.89%

Winner

COYA

-10.71%

5Y(CAGR)

AGEN

-50.73%

COYA

N/A

10Y(CAGR)

AGEN

-27.90%

COYA

N/A

Max(CAGR)

AGEN

-24.78%

Winner

COYA

+2.15%

AGEN vs COYA - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	AGEN	COYA
2026	-7.12%	-12.92%
2025	+1.62%	+1.58%
2024	-82.88%	-17.67%
2023	-64.85%	+59.35%
2022	-30.84%	+3.68%
2021	-0.31%	N/A
2020	-21.29%	N/A
2019	+62.15%	N/A
2018	-32.77%	N/A
2017	-21.63%	N/A
2016	-7.62%	N/A
2015	+14.07%	N/A
2014	+42.81%	N/A
2013	-37.74%	N/A
2012	+88.94%	N/A
2011	-68.55%	N/A
2010	+57.17%	N/A
2009	+33.33%	N/A
2008	-76.92%	N/A
2007	+6.25%	N/A
2006	-61.80%	N/A
2005	-52.40%	N/A
2004	-11.69%	N/A
2003	+5.98%	N/A
2002	-33.89%	N/A
2001	+48.28%	N/A
2000	-76.09%	N/A

AGEN vs COYA Drawdown Comparison

The maximum drawdown for AGEN was -99.98%, occurring on Mar 31, 2025. This drawdown has not yet recovered.

The maximum drawdown for COYA was -62.90%, occurring on Mar 30, 2026. This drawdown has not yet recovered.

The current AGEN drawdown is -99.95%. The current COYA drawdown is -51.72%.

Rank	AGEN	COYA
#1	-99.98% Mar 9, 2000 - Mar 31, 2025	-62.90% Oct 28, 2024 - Mar 30, 2026
#2	-23.90% Feb 16, 2000 - Mar 9, 2000	-52.47% Mar 15, 2024 - Oct 28, 2024
#3	-6.50% Feb 10, 2000 - Feb 15, 2000	-43.40% May 16, 2023 - Dec 1, 2023
#4	-4.86% Feb 8, 2000 - Feb 10, 2000	-26.35% Dec 28, 2023 - Feb 14, 2024
#5	N/A	-22.62% Jan 10, 2023 - May 4, 2023
#6	N/A	-10.40% Mar 4, 2024 - Mar 15, 2024
#7	N/A	-8.47% Dec 19, 2023 - Dec 27, 2023
#8	N/A	-7.14% Dec 5, 2023 - Dec 19, 2023
#9	N/A	-5.86% Feb 28, 2024 - Mar 1, 2024
#10	N/A	-3.74% May 10, 2023 - May 16, 2023
#11	N/A	-3.39% Feb 23, 2024 - Feb 27, 2024
#12	N/A	-2.49% Dec 30, 2022 - Jan 10, 2023
#13	N/A	-1.70% Feb 15, 2024 - Feb 20, 2024
#14	N/A	-0.92% Feb 21, 2024 - Feb 23, 2024
#15	N/A	-0.19% May 8, 2023 - May 10, 2023

Correlation

Correlation between AGEN and COYA is -0.41 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.41

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