AGEN vs CRDL

Comparison between Agenus Inc (AGEN, Company) and Cardiol Therapeutics Inc - Class A (CRDL, Company).

Both AGEN and CRDL are from the Healthcare sector.

5-Year PerformanceCRDL has outperformed AGEN, delivering a return of -14.7% compared to -50.7%

AGEN vs CRDL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AGEN(COMPANY)	CRDL(COMPANY)
Market Cap	$116M	$116M
Max Drawdown	99.98%	92.71%
Sharpe Ratio	-0.16	-0.08
5Y Beta	1.42	1.31
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	1.80	-3.75
Forward P/E	1.32	N/A
5Y EPS CAGR	N/A	-10.43%
Debt to Equity	-27.30%	0.48%
Free Cash Flow Yield	-75.74%	-15.22%

Market Cap

Winner

AGEN

$116M

CRDL

$116M

Max Drawdown

AGEN

99.98%

Winner

CRDL

92.71%

Sharpe Ratio

AGEN

-0.16

Winner

CRDL

-0.08

5Y Beta

AGEN

1.42

Winner

CRDL

1.31

Industry

AGEN

Biotechnology

CRDL

Drug Manufacturers - Specialty & Generic

P/E Ratio

AGEN

1.80

Winner

CRDL

-3.75

Forward P/E

AGEN

1.32

CRDL

N/A

5Y EPS CAGR

AGEN

N/A

CRDL

-10.43%

Debt to Equity

Winner

AGEN

-27.30%

CRDL

0.48%

Free Cash Flow Yield

AGEN

-75.74%

Winner

CRDL

-15.22%

AGEN vs CRDL - Historical Returns

Returns include dividend reinvestment.

Period	AGEN	CRDL
1 month	-5.06%	-17.19%
3 months	-20.21%	+7.41%
6 months	-14.53%	+4.95%
1 year	-32.89%	-19.70%
5 years(CAGR)	-50.73%	-14.72%
10 years(CAGR)	-27.90%	N/A
Max(CAGR)	-24.78%	-15.63%

Winner

AGEN

-5.06%

CRDL

-17.19%

AGEN

-20.21%

Winner

CRDL

+7.41%

AGEN

-14.53%

Winner

CRDL

+4.95%

AGEN

-32.89%

Winner

CRDL

-19.70%

5Y(CAGR)

AGEN

-50.73%

Winner

CRDL

-14.72%

10Y(CAGR)

AGEN

-27.90%

CRDL

N/A

Max(CAGR)

AGEN

-24.78%

Winner

CRDL

-15.63%

AGEN vs CRDL - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	AGEN	CRDL
2026	-7.12%	+6.62%
2025	+1.62%	-30.38%
2024	-82.88%	+45.45%
2023	-64.85%	+56.12%
2022	-30.84%	-72.58%
2021	-0.31%	-13.65%
2020	-21.29%	-39.59%
2019	+62.15%	-5.49%
2018	-32.77%	N/A
2017	-21.63%	N/A
2016	-7.62%	N/A
2015	+14.07%	N/A
2014	+42.81%	N/A
2013	-37.74%	N/A
2012	+88.94%	N/A
2011	-68.55%	N/A
2010	+57.17%	N/A
2009	+33.33%	N/A
2008	-76.92%	N/A
2007	+6.25%	N/A
2006	-61.80%	N/A
2005	-52.40%	N/A
2004	-11.69%	N/A
2003	+5.98%	N/A
2002	-33.89%	N/A
2001	+48.28%	N/A
2000	-76.09%	N/A

AGEN vs CRDL Drawdown Comparison

The maximum drawdown for AGEN was -99.98%, occurring on Mar 31, 2025. This drawdown has not yet recovered.

The maximum drawdown for CRDL was -92.71%, occurring on Apr 5, 2023. This drawdown has not yet recovered.

The current AGEN drawdown is -99.95%. The current CRDL drawdown is -82.88%.

Rank	AGEN	CRDL
#1	-99.98% Mar 9, 2000 - Mar 31, 2025	-92.71% Feb 22, 2019 - Apr 5, 2023
#2	-23.90% Feb 16, 2000 - Mar 9, 2000	-9.26% Feb 4, 2019 - Feb 19, 2019
#3	-6.50% Feb 10, 2000 - Feb 15, 2000	-1.86% Jan 18, 2019 - Jan 29, 2019
#4	-4.86% Feb 8, 2000 - Feb 10, 2000	-0.20% Jan 16, 2019 - Jan 18, 2019