COYA vs AGEN

Comparison between Coya Therapeutics Inc (COYA, Company) and Agenus Inc (AGEN, Company).

Both COYA and AGEN are from the Healthcare sector.

COYA vs AGEN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	COYA(COMPANY)	AGEN(COMPANY)
Market Cap	$115M	$116M
Max Drawdown	62.90%	99.98%
Sharpe Ratio	0.14	-0.16
5Y Beta	1.08	1.42
Industry	Biotechnology	Biotechnology
P/E Ratio	-4.60	1.80
Forward P/E	N/A	1.32
PEG Ratio	-9.50	N/A
Debt to Equity	0.00%	-27.30%
Free Cash Flow Yield	-12.23%	-75.74%

Market Cap

COYA

$115M

Winner

AGEN

$116M

Max Drawdown

Winner

COYA

62.90%

AGEN

99.98%

Sharpe Ratio

Winner

COYA

0.14

AGEN

-0.16

5Y Beta

Winner

COYA

1.08

AGEN

1.42

Industry

COYA

Biotechnology

AGEN

Biotechnology

P/E Ratio

Winner

COYA

-4.60

AGEN

1.80

Forward P/E

COYA

N/A

AGEN

1.32

PEG Ratio

COYA

-9.50

AGEN

N/A

Debt to Equity

COYA

0.00%

Winner

AGEN

-27.30%

Free Cash Flow Yield

Winner

COYA

-12.23%

AGEN

-75.74%

COYA vs AGEN - Historical Returns

Returns include dividend reinvestment.

Period	COYA	AGEN
1 month	+0.00%	-5.06%
3 months	+10.56%	-20.21%
6 months	-7.17%	-14.53%
1 year	-10.71%	-32.89%
5 years(CAGR)	N/A	-50.73%
10 years(CAGR)	N/A	-27.90%
Max(CAGR)	+2.15%	-24.78%

Winner

COYA

+0.00%

AGEN

-5.06%

Winner

COYA

+10.56%

AGEN

-20.21%

Winner

COYA

-7.17%

AGEN

-14.53%

Winner

COYA

-10.71%

AGEN

-32.89%

5Y(CAGR)

COYA

N/A

AGEN

-50.73%

10Y(CAGR)

COYA

N/A

AGEN

-27.90%

Max(CAGR)

Winner

COYA

+2.15%

AGEN

-24.78%

COYA vs AGEN - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	COYA	AGEN
2026	-12.92%	-7.12%
2025	+1.58%	+1.62%
2024	-17.67%	-82.88%
2023	+59.35%	-64.85%
2022	+3.68%	-30.84%
2021	N/A	-0.31%
2020	N/A	-21.29%
2019	N/A	+62.15%
2018	N/A	-32.77%
2017	N/A	-21.63%
2016	N/A	-7.62%
2015	N/A	+14.07%
2014	N/A	+42.81%
2013	N/A	-37.74%
2012	N/A	+88.94%
2011	N/A	-68.55%
2010	N/A	+57.17%
2009	N/A	+33.33%
2008	N/A	-76.92%
2007	N/A	+6.25%
2006	N/A	-61.80%
2005	N/A	-52.40%
2004	N/A	-11.69%
2003	N/A	+5.98%
2002	N/A	-33.89%
2001	N/A	+48.28%
2000	N/A	-76.09%

COYA vs AGEN Drawdown Comparison

The maximum drawdown for COYA was -62.90%, occurring on Mar 30, 2026. This drawdown has not yet recovered.

The maximum drawdown for AGEN was -99.98%, occurring on Mar 31, 2025. This drawdown has not yet recovered.

The current COYA drawdown is -51.72%. The current AGEN drawdown is -99.95%.

Rank	COYA	AGEN
#1	-62.90% Oct 28, 2024 - Mar 30, 2026	-99.98% Mar 9, 2000 - Mar 31, 2025
#2	-52.47% Mar 15, 2024 - Oct 28, 2024	-23.90% Feb 16, 2000 - Mar 9, 2000
#3	-43.40% May 16, 2023 - Dec 1, 2023	-6.50% Feb 10, 2000 - Feb 15, 2000
#4	-26.35% Dec 28, 2023 - Feb 14, 2024	-4.86% Feb 8, 2000 - Feb 10, 2000
#5	-22.62% Jan 10, 2023 - May 4, 2023	N/A
#6	-10.40% Mar 4, 2024 - Mar 15, 2024	N/A
#7	-8.47% Dec 19, 2023 - Dec 27, 2023	N/A
#8	-7.14% Dec 5, 2023 - Dec 19, 2023	N/A
#9	-5.86% Feb 28, 2024 - Mar 1, 2024	N/A
#10	-3.74% May 10, 2023 - May 16, 2023	N/A
#11	-3.39% Feb 23, 2024 - Feb 27, 2024	N/A
#12	-2.49% Dec 30, 2022 - Jan 10, 2023	N/A
#13	-1.70% Feb 15, 2024 - Feb 20, 2024	N/A
#14	-0.92% Feb 21, 2024 - Feb 23, 2024	N/A
#15	-0.19% May 8, 2023 - May 10, 2023	N/A

Correlation

Correlation between COYA and AGEN is -0.41 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.41

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