CNTA vs PTCT

Comparison between Centessa Pharmaceuticals plc (CNTA, Company) and PTC Therapeutics Inc (PTCT, Company).

Both CNTA and PTCT are from the Healthcare sector.

5-Year PerformancePTCT has outperformed CNTA, delivering a return of +12.9% compared to +12.8%

CNTA vs PTCT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CNTA(COMPANY)	PTCT(COMPANY)
Market Cap	$6.12B	$6.09B
Max Drawdown	88.19%	94.60%
Sharpe Ratio	1.95	1.18
5Y Beta	1.14	1.06
Industry	Biotechnology	Biotechnology
P/E Ratio	-22.75	-31.82
Forward P/E	N/A	55.25
PEG Ratio	N/A	0.81
5Y EPS CAGR	N/A	-16.59%
Debt to Equity	22.66%	-159.00%
Free Cash Flow Yield	-3.42%	-3.72%
P/S Ratio	409.21	7.37
P/B Ratio	12.57	1743.27

Market Cap

Winner

CNTA

$6.12B

PTCT

$6.09B

Max Drawdown

Winner

CNTA

88.19%

PTCT

94.60%

Sharpe Ratio

Winner

CNTA

1.95

PTCT

1.18

5Y Beta

CNTA

1.14

Winner

PTCT

1.06

Industry

CNTA

Biotechnology

PTCT

Biotechnology

P/E Ratio

CNTA

-22.75

Winner

PTCT

-31.82

Forward P/E

CNTA

N/A

PTCT

55.25

PEG Ratio

CNTA

N/A

PTCT

0.81

5Y EPS CAGR

CNTA

N/A

PTCT

-16.59%

Debt to Equity

CNTA

22.66%

Winner

PTCT

-159.00%

Free Cash Flow Yield

Winner

CNTA

-3.42%

PTCT

-3.72%

P/S Ratio

CNTA

409.21

Winner

PTCT

7.37

P/B Ratio

Winner

CNTA

12.57

PTCT

1743.27

CNTA vs PTCT - Historical Returns

Returns include dividend reinvestment.

Period	CNTA	PTCT
1 month	-0.05%	-3.15%
3 months	+58.31%	+1.77%
6 months	+39.77%	-8.53%
1 year	+223.33%	+49.38%
5 years(CAGR)	+12.83%	+12.90%
10 years(CAGR)	N/A	+26.22%
Max(CAGR)	+12.83%	+11.87%

Winner

CNTA

-0.05%

PTCT

-3.15%

Winner

CNTA

+58.31%

PTCT

+1.77%

Winner

CNTA

+39.77%

PTCT

-8.53%

Winner

CNTA

+223.33%

PTCT

+49.38%

5Y(CAGR)

CNTA

+12.83%

Winner

PTCT

+12.90%

10Y(CAGR)

CNTA

N/A

PTCT

+26.22%

Max(CAGR)

Winner

CNTA

+12.83%

PTCT

+11.87%

CNTA vs PTCT - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	CNTA	PTCT
2026	+67.33%	-8.59%
2025	+42.91%	+65.56%
2024	+108.59%	+60.98%
2023	+154.31%	-27.78%
2022	-73.25%	-10.36%
2021	-48.23%	-34.17%
2020	N/A	+25.99%
2019	N/A	+42.90%
2018	N/A	+96.56%
2017	N/A	+48.53%
2016	N/A	-64.65%
2015	N/A	-36.47%
2014	N/A	+209.26%
2013	N/A	+2.91%

CNTA vs PTCT Drawdown Comparison

The maximum drawdown for CNTA was -88.19%, occurring on Feb 16, 2023. Recovery took 1107 trading sessions.

The maximum drawdown for PTCT was -94.60%, occurring on Nov 3, 2016. Recovery took 2689 trading sessions.

The current CNTA drawdown is -0.55%. The current PTCT drawdown is -18.67%.

Rank	CNTA	PTCT
#1	-88.19% Jun 17, 2021 - Nov 12, 2025	-94.60% Mar 17, 2015 - Nov 21, 2025
#2	-26.38% Dec 5, 2025 - Mar 31, 2026	-56.81% Feb 27, 2014 - Sep 15, 2014
#3	-13.54% Jun 2, 2021 - Jun 17, 2021	-39.55% Sep 23, 2013 - Jan 15, 2014
#4	-3.06% Nov 24, 2025 - Dec 4, 2025	-27.17% Nov 26, 2025 - Mar 6, 2026
#5	-2.89% Nov 18, 2025 - Nov 24, 2025	-25.36% Sep 26, 2014 - Dec 2, 2014
#6	-2.73% Nov 12, 2025 - Nov 14, 2025	-25.27% Jan 17, 2014 - Feb 20, 2014
#7	-1.10% Apr 1, 2026 - Apr 30, 2026	-23.59% Jul 18, 2013 - Sep 4, 2013
#8	-1.05% Nov 14, 2025 - Nov 18, 2025	-22.29% Jun 25, 2013 - Jul 17, 2013
#9	N/A	-19.59% Jan 20, 2015 - Feb 23, 2015
#10	N/A	-18.21% Sep 10, 2013 - Sep 23, 2013
#11	N/A	-13.33% Dec 12, 2014 - Dec 19, 2014
#12	N/A	-10.21% Dec 19, 2014 - Jan 13, 2015
#13	N/A	-6.13% Feb 25, 2015 - Mar 11, 2015
#14	N/A	-3.04% Dec 9, 2014 - Dec 11, 2014
#15	N/A	-2.36% Mar 12, 2015 - Mar 17, 2015