CNTA vs SPY
Comparison between Centessa Pharmaceuticals plc (CNTA, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed CNTA, delivering a return of +13.9% compared to +12.8%
CNTA vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
CNTA
$6.12B
Winner
SPY
$735B
Expense Ratio
CNTA
N/A
SPY
0.09%
Max Drawdown
CNTA
88.19%
Winner
SPY
56.47%
Sharpe Ratio
Winner
CNTA
1.95
SPY
1.71
5Y Beta
CNTA
1.14
Winner
SPY
1.00
Industry
CNTA
Biotechnology
SPY
N/A
P/E Ratio
Winner
CNTA
-22.75
SPY
28.81
Forward P/E
CNTA
N/A
SPY
22.10
5Y Dividends CAGR
CNTA
N/A
SPY
5.43%
5Y EPS CAGR
CNTA
N/A
SPY
25.84%
Debt to Equity
Winner
CNTA
22.66%
SPY
34.16%
Free Cash Flow Yield
CNTA
-3.42%
SPY
N/A
P/S Ratio
CNTA
409.21
Winner
SPY
3.69
P/B Ratio
CNTA
12.57
Winner
SPY
5.54
CNTA vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
CNTA
-0.05%
Winner
SPY
+4.01%
3M
Winner
CNTA
+58.31%
SPY
+7.93%
6M
Winner
CNTA
+39.77%
SPY
+12.54%
1Y
Winner
CNTA
+223.33%
SPY
+25.60%
5Y(CAGR)
CNTA
+12.83%
Winner
SPY
+13.94%
10Y(CAGR)
CNTA
N/A
SPY
+15.56%
Max(CAGR)
Winner
CNTA
+12.83%
SPY
+8.49%
CNTA vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | CNTA | SPY |
|---|---|---|
| 2026 | +67.33% | +8.42% |
| 2025 | +42.91% | +18.00% |
| 2024 | +108.59% | +25.59% |
| 2023 | +154.31% | +26.72% |
| 2022 | -73.25% | -18.64% |
| 2021 | -48.23% | +30.52% |
| 2020 | N/A | +17.28% |
| 2019 | N/A | +31.09% |
| 2018 | N/A | -5.24% |
| 2017 | N/A | +20.78% |
| 2016 | N/A | +13.59% |
| 2015 | N/A | +1.31% |
| 2014 | N/A | +14.56% |
| 2013 | N/A | +29.00% |
| 2012 | N/A | +14.17% |
| 2011 | N/A | +0.85% |
| 2010 | N/A | +13.14% |
| 2009 | N/A | +22.67% |
| 2008 | N/A | -36.25% |
| 2007 | N/A | +5.32% |
| 2006 | N/A | +13.85% |
| 2005 | N/A | +5.32% |
| 2004 | N/A | +10.75% |
| 2003 | N/A | +24.18% |
| 2002 | N/A | -22.42% |
| 2001 | N/A | -10.13% |
| 2000 | N/A | -8.84% |
| 1999 | N/A | +8.61% |
CNTA vs SPY Drawdown Comparison
The maximum drawdown for CNTA was -88.19%, occurring on Feb 16, 2023. Recovery took 1107 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current CNTA drawdown is -0.55%. The current SPY drawdown is -1.27%.
| Rank | CNTA | SPY |
|---|---|---|
| #1 | -88.19% Jun 17, 2021 - Nov 12, 2025 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -26.38% Dec 5, 2025 - Mar 31, 2026 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -13.54% Jun 2, 2021 - Jun 17, 2021 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -3.06% Nov 24, 2025 - Dec 4, 2025 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -2.89% Nov 18, 2025 - Nov 24, 2025 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -2.73% Nov 12, 2025 - Nov 14, 2025 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -1.10% Apr 1, 2026 - Apr 30, 2026 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -1.05% Nov 14, 2025 - Nov 18, 2025 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | N/A | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | N/A | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | N/A | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | N/A | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | N/A | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | N/A | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | N/A | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between CNTA and SPY is 0.78 which considered as a strong positive correlation - the stocks tend to move together.
0.78
-101
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